FB2024_03 , released June 25, 2024
Allele: Dmel\Doa4
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General Information
Symbol
Dmel\Doa4
Species
D. melanogaster
Name
FlyBase ID
FBal0002722
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
DoaEMS-2
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology

Polytene chromosomes normal.

Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

DoaE786/Doa4 XX females show somatic sex transformations. The flies exhibit typical female pigmentation but a male clasper, female vaginal structures and the female genital sex comb.

The wings of Doa4/Doaγ3A mutant flies have blackened veins.

In Doa4/Doaγ3A mutants where the Doa4 allele is from the mother the flies have badly oriented bristles on the head, missing or duplicated dorso-central bristles, forked scutellar bristles, fragile wings with incomplete posterior crossveins and darkened areas within the veins. When the Doaγ3A allele comes from the mother there are no survivors.

Homozygous clones are recovered in eyes and cuticles when clones are induced during first instar and later larval periods. The mutant clones show essentially normal retinal organisation.

Eye colour: darker than apricot in males.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

Doa4 is an enhancer of phenotype of wsp55

NOT Enhancer of
Statement
Reference

Doa4 is a non-enhancer of phenotype of wa57i11

Doa4 is a non-enhancer of phenotype of wa58l

Doa4 is a non-enhancer of phenotype of wa2

Doa4 is a non-enhancer of phenotype of wr

Doa4 is a non-enhancer of phenotype of wIR5

Doa4 is a non-enhancer of phenotype of wa3

Doa4 is a non-enhancer of phenotype of wsp81d

Doa4 is a non-enhancer of phenotype of wa59k1

Doa4 is a non-enhancer of phenotype of wsp2

Doa4 is a non-enhancer of phenotype of wec3

Doa4 is a non-enhancer of phenotype of wapl

Doa4 is a non-enhancer of phenotype of wIR2

Doa4 is a non-enhancer of phenotype of wE

Doa4 is a non-enhancer of phenotype of wsat

Doa4 is a non-enhancer of phenotype of wbl

Doa4 is a non-enhancer of phenotype of wBwx

Doa4 is a non-enhancer of phenotype of wa4

Doa4 is a non-enhancer of phenotype of wcol

Doa4 is a non-enhancer of phenotype of we2

Doa4 is a non-enhancer of phenotype of wco

Doa4 is a non-enhancer of phenotype of wi

Doa4 is a non-enhancer of phenotype of wIR4

Doa4 is a non-enhancer of phenotype of wIR3

Doa4 is a non-enhancer of phenotype of wIR6

Doa4 is a non-enhancer of phenotype of wmo

Doa4 is a non-enhancer of phenotype of wIR1

Doa4 is a non-enhancer of phenotype of wh

Doa4 is a non-enhancer of phenotype of wbf2

Doa4 is a non-enhancer of phenotype of wzm

Doa4 is a non-enhancer of phenotype of wbf

Doa4 is a non-enhancer of phenotype of we

Suppressor of
Statement
Reference

Doa4 is a suppressor of phenotype of waM

Doa4 is a suppressor of phenotype of waR84h

Doa4 is a suppressor of phenotype of wa

NOT Suppressor of
Statement
Reference

Doa4 is a non-suppressor of phenotype of wa57i11

Doa4 is a non-suppressor of phenotype of wa58l

Doa4 is a non-suppressor of phenotype of wsp2

Doa4 is a non-suppressor of phenotype of wec3

Doa4 is a non-suppressor of phenotype of wIR2

Doa4 is a non-suppressor of phenotype of wbl

Doa4 is a non-suppressor of phenotype of wcol

Doa4 is a non-suppressor of phenotype of we2

Doa4 is a non-suppressor of phenotype of wIR4

Doa4 is a non-suppressor of phenotype of wIR6

Doa4 is a non-suppressor of phenotype of wmo

Doa4 is a non-suppressor of phenotype of wBwx

Doa4 is a non-suppressor of phenotype of wE

Doa4 is a non-suppressor of phenotype of wa3

Doa4 is a non-suppressor of phenotype of wa4

Doa4 is a non-suppressor of phenotype of wapl

Doa4 is a non-suppressor of phenotype of wbf

Doa4 is a non-suppressor of phenotype of wbf2

Doa4 is a non-suppressor of phenotype of wco

Doa4 is a non-suppressor of phenotype of we

Doa4 is a non-suppressor of phenotype of wh

Doa4 is a non-suppressor of phenotype of wi

Doa4 is a non-suppressor of phenotype of wsat

Doa4 is a non-suppressor of phenotype of wIR3

Doa4 is a non-suppressor of phenotype of wzm

Doa4 is a non-suppressor of phenotype of wIR1

Doa4 is a non-suppressor of phenotype of wa2

Doa4 is a non-suppressor of phenotype of wr

Doa4 is a non-suppressor of phenotype of wIR5

Doa4 is a non-suppressor of phenotype of wsp81d

Doa4 is a non-suppressor of phenotype of wa59k1

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (3)