FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term lethal ID (Ontology) FBcv:0000351 (FlyBase CV)
Definition A phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012).
Comment
Links to Extrernal Ontologies
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPIC_CLASS   25105
Insertions (FBti)  LETHALITY    6675
Constructs (FBtp)  PHENOTYPIC_CLASS    3877
Constructs (FBtp)  USES       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Insertions Constructs
 lethal (all annotations which use CV term, excluding "NOT" statements)   25105   6675   3879
     lethal | abnormal dorsal/ventral axis specification | maternal effect       2       --       --
     lethal | abnormal dorsal/ventral axis specification | maternal effect | recessive       2       --       --
     lethal | adult stage      34     25      2
     lethal | adult stage | female       --       1       --
     lethal | adult stage | female | cold sensitive       2       --       --
     lethal | adult stage | heat sensitive      13       --       --
     lethal | adult stage | recessive       9      2       --
     lethal | adult stage | recessive | heat sensitive       1       --       --
     lethal | cell autonomous | recessive | somatic clone       1       --       --
     lethal | chemical conditional      11       --       9
     lethal | chemical conditional | recessive       1       --       --
     lethal | cold sensitive      81       --      39
     lethal | conditional      23       --       7
     lethal | conditional | embryonic stage       3       --       3
     lethal | conditional | pupal stage       1       --       --
     lethal | conditional | recessive      14       --       --
     lethal | dominant      26      4      9
     lethal | dominant | cold sensitive      26       --       --
     lethal | dominant | embryonic stage | maternal effect       1      1       --
     lethal | dominant | heat sensitive      43       --       5
     lethal | dominant | male       6      5       --
     lethal | dominant | male limited       2      1       --
     lethal | dominant | maternal effect      31      1      6
     lethal | dominant | maternal effect | heat sensitive       1       --       --
     lethal | dominant | non-rescuable maternal effect       1       --       --
     lethal | dominant | pupal stage | heat sensitive       1       --       --
     lethal | egg stage | maternal effect       6       --       --
     lethal | embryonic stage     117     26     47
     lethal | embryonic stage | germline clone      15      1       --
     lethal | embryonic stage | germline clone | maternal effect       8      1       --
     lethal | embryonic stage | germline clone | maternal effect | recessive      16      3       --
     lethal | embryonic stage | germline clone | neurogenic phenotype | recessive       1       --       --
     lethal | embryonic stage | germline clone | non-rescuable maternal effect       1       --       --
     lethal | embryonic stage | germline clone | non-rescuable maternal effect | recessive      31       --       --
     lethal | embryonic stage | germline clone | recessive       1      1       --
     lethal | embryonic stage | germline clone | recessive | rescuable maternal effect       8       --       --
     lethal | embryonic stage | germline clone | rescuable maternal effect       7       --       --
     lethal | embryonic stage | heat sensitive      11       --       6
     lethal | embryonic stage | homeotic | recessive       1       --       --
     lethal | embryonic stage | male | recessive       1       --       --
     lethal | embryonic stage | maternal effect      26     17       --
     lethal | embryonic stage | maternal effect | recessive      35      9       --
     lethal | embryonic stage | maternal effect | recessive | heat sensitive       1       --       --
     lethal | embryonic stage | non-rescuable maternal effect       3       --       --
     lethal | embryonic stage | non-rescuable maternal effect | recessive       8      2       --
     lethal | embryonic stage | non-rescuable maternal effect | recessive | heat sensitive       1       --       --
     lethal | embryonic stage | recessive      80     25       --
     lethal | embryonic stage | recessive | heat sensitive       1       --       --
     lethal | embryonic stage | recessive | rescuable maternal effect      14      6       --
     lethal | embryonic stage | rescuable maternal effect      22     12       --
     lethal | embryonic stage | rescuable maternal effect | cold sensitive       1       --       --
     lethal | female      91     17     44
     lethal | female limited     138      4    129
     lethal | female limited | cold sensitive       2       --       1
     lethal | female limited | maternal effect       2      2       --
     lethal | female limited | pupal stage       3       --       --
     lethal | female limited | recessive       3      1       --
     lethal | female limited | temperature conditional       2       --       --
     lethal | female | first instar larval stage | recessive       1       --       --
     lethal | female | heat sensitive      10       --       7
     lethal | female | maternal effect | heat sensitive       4       --       --
     lethal | female | maternal effect | recessive       1       --       --
     lethal | female | pupal stage       3      1      1
     lethal | female | recessive      39      4       --
     lethal | female | recessive | heat sensitive       2       --       --
     lethal | first instar larval stage      44     17     20
     lethal | first instar larval stage | germline clone       1      1       --
     lethal | first instar larval stage | germline clone | maternal effect       1       --       --
     lethal | first instar larval stage | heat sensitive       4       --       4
     lethal | first instar larval stage | male | recessive       1       --       --
     lethal | first instar larval stage | maternal effect | recessive       1       --       --
     lethal | first instar larval stage | recessive      20      3       --
     lethal | gap | heat sensitive       1       --       --
     lethal | germline clone      15       --       --
     lethal | germline clone | larval stage       3       --       2
     lethal | germline clone | larval stage | recessive       5      3       --
     lethal | germline clone | late embryonic stage       3      1       --
     lethal | germline clone | male limited       1      1       --
     lethal | germline clone | male | rescuable maternal effect       1      1       --
     lethal | germline clone | mammalian oogenesis stage       1       --       --
     lethal | germline clone | maternal effect      11      4       --
     lethal | germline clone | maternal effect | neurogenic phenotype | recessive       2       --       --
     lethal | germline clone | maternal effect | recessive      22      1       --
     lethal | germline clone | neurogenic phenotype       1       --       --
     lethal | germline clone | neurogenic phenotype | recessive       1       --       --
     lethal | germline clone | neurogenic phenotype | recessive | rescuable maternal effect       1       --       --
     lethal | germline clone | non-rescuable maternal effect       2      2       --
     lethal | germline clone | pharate adult stage       1      1       --
     lethal | germline clone | pharate adult stage | recessive       2       --       --
     lethal | germline clone | recessive       6       --       --
     lethal | germline clone | recessive | rescuable maternal effect      10      1       --
     lethal | germline clone | rescuable maternal effect       7       --       --
     lethal | heat sensitive     550       --     208
     lethal | homeotic      10       --       --
     lethal | homeotic | recessive      13       --       --
     lethal | larval stage     228     77     71
     lethal | larval stage | heat sensitive      17       --      13
     lethal | larval stage | male       2       --       --
     lethal | larval stage | maternal effect       4       --       --
     lethal | larval stage | maternal effect | recessive       2       --       --
     lethal | larval stage | partially | recessive       1       --       --
     lethal | larval stage | recessive     153     56       --
     lethal | larval stage | recessive | heat sensitive       1       --       --
     lethal | larval stage | somatic clone       2       --       2
     lethal | larval stage | temperature conditional       2       --       3
     lethal | late embryonic stage       5      5       --
     lethal | late third instar larval stage       3       --       2
     lethal | late third instar larval stage | recessive       1       --       --
     lethal | male     166     15     71
     lethal | male limited     138      5    126
     lethal | male limited | chemical conditional       2       --       2
     lethal | male limited | cold sensitive      81       --      81
     lethal | male limited | heat sensitive       2       --       3
     lethal | male limited | maternal effect       1       --       1
     lethal | male limited | recessive       1       --       --
     lethal | male limited | third instar larval stage       2       --       1
     lethal | male limited | third instar larval stage | temperature conditional       2       --       2
     lethal | male | cold sensitive       1       --       --
     lethal | male | heat sensitive      11       --       6
     lethal | male | pharate adult stage       2       --       1
     lethal | male | pupal stage       2       --       --
     lethal | male | recessive      53      2       --
     lethal | male | recessive | cold sensitive       1       --       --
     lethal | male | recessive | heat sensitive       1       --       --
     lethal | maternal effect     261     27     17
     lethal | maternal effect | cold sensitive       3       --       --
     lethal | maternal effect | heat sensitive      17       --       --
     lethal | maternal effect | non-rescuable maternal effect       1       --       --
     lethal | maternal effect | pupal stage       2       --       --
     lethal | maternal effect | recessive     298     21       --
     lethal | maternal effect | recessive | cold sensitive       8       --       --
     lethal | maternal effect | recessive | heat sensitive      15       --       --
     lethal | maternal effect | semidominant       1       --       --
     lethal | maternal effect | somatic clone       1      1       --
     lethal | neurogenic phenotype       9       --       --
     lethal | neurogenic phenotype | heat sensitive       2       --       2
     lethal | neurogenic phenotype | recessive      10      1       --
     lethal | neurogenic phenotype | recessive | heat sensitive       1       --       --
     lethal | neurogenic phenotype | rescuable maternal effect       2       --       --
     lethal | non-rescuable maternal effect       6      1       --
     lethal | non-rescuable maternal effect | heat sensitive       1       --       --
     lethal | non-rescuable maternal effect | recessive      18      1       --
     lethal | non-rescuable maternal effect | recessive | heat sensitive       1       --       --
     lethal | nutrition conditional      15       --      11
     lethal | P-stage      38      2     23
     lethal | P-stage | recessive      11       --       --
     lethal | parental effect       3      1      2
     lethal | partially | heat sensitive       2       --       --
     lethal | partially | pupal stage | recessive       1       --       --
     lethal | paternal effect       9       --       6
     lethal | paternal effect | recessive       2       --       --
     lethal | pharate adult stage     157     83     33
     lethal | pharate adult stage P10       2       --       --
     lethal | pharate adult stage P14       2       --       3
     lethal | pharate adult stage P15       9       --       8
     lethal | pharate adult stage P15(ii)       4       --       3
     lethal | pharate adult stage P8 | heat sensitive       1       --       1
     lethal | pharate adult stage | heat sensitive       4       --       3
     lethal | pharate adult stage | recessive      17      7       --
     lethal | pharate adult stage | temperature conditional       1       --       1
     lethal | prepupal stage      69     60      1
     lethal | prepupal stage P1       1       --       1
     lethal | prepupal stage P2       2       --       --
     lethal | prepupal stage P4(ii)       1       --       1
     lethal | prepupal stage | heat sensitive       2       --       2
     lethal | prepupal stage | recessive       4      1       --
     lethal | pupal stage     486    109    311
     lethal | pupal stage P5       7       --       3
     lethal | pupal stage P5(i)       1       --       1
     lethal | pupal stage P7       2       --       1
     lethal | pupal stage | cold sensitive       3       --       2
     lethal | pupal stage | heat sensitive      16       --      15
     lethal | pupal stage | recessive      95     34       --
     lethal | pupal stage | recessive | heat sensitive       2       --       --
     lethal | pupal stage | recessive | somatic clone       2       --       --
     lethal | pupal stage | somatic clone       4       --       2
     lethal | pupal stage | temperature conditional       3       --       4
     lethal | recessive   14389   5227     17
     lethal | recessive | cold sensitive      42       --       --
     lethal | recessive | heat sensitive     161       --       2
     lethal | recessive | rescuable maternal effect      15      4       --
     lethal | recessive | rescuable maternal effect | heat sensitive       1       --       --
     lethal | recessive | second instar larval stage       9       --       --
     lethal | recessive | temperature conditional       3       --       --
     lethal | recessive | third instar larval stage       8      4       --
     lethal | recessive | third instar larval stage | heat sensitive       1       --       --
     lethal | rescuable maternal effect      92      3       --
     lethal | rescuable maternal effect | heat sensitive       1       --       --
     lethal | RU486 conditional      19       --      12
     lethal | second instar larval stage      21      6      8
     lethal | semidominant      11       --       --
     lethal | semidominant | cold sensitive       1       --       --
     lethal | semidominant | heat sensitive       1       --       --
     lethal | somatic clone      18      2      5
     lethal | somatic clone | third instar larval stage       1       --       --
     lethal | temperature conditional      20       --      13
     lethal | tetracycline conditional       3       --       2
     lethal | third instar larval stage      33      6     16
Spanning Tree (Parents/Children)
Only view relationship:
  increased mortality
   |__increased mortality during development
       |__lethal  46420 rec.
           |__lethal - all die before end of P-stage 17363 rec.
           |   |__lethal - all die before end of pupal stage(+) 14884 rec.
           |   |__lethal - all die during P-stage(+) 2057 rec.
           |__lethal - all die during immature adult stage 6 rec.
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