FB2024_03 , released June 25, 2024
Allele: Dmel\wE
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General Information
Symbol
Dmel\wE
Species
D. melanogaster
Name
FlyBase ID
FBal0040134
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{wE}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Bhadra et al., 1997, Bhadra et al., 1997, Rabinow and Birchler, 1989, Levis et al., 1985)
Progenitor genotype
w+t9.8
(Levis et al., 1985)
Carried in construct
P{wE}
Cytology
Description

Deletion of cis regulatory region 5' to BglII site.

(Bhadra et al., 1997)

Construct: w promoter sequences up to 1039bp drive w gene expression.

(Bhadra et al., 1997)

Deletion of cis-regulatory region 5' to BglII site.

(Bhadra and Birchler, 1996)

Synthetic deletion of regulatory region 5' to BglII at +4.79kb.

(Rabinow and Birchler, 1989)

8.0kb fragment including 2.1kb of 3' flanking sequences, 1.1kb of 5' flanking sequences and the complete w transcription unit.

(Levis et al., 1985)
Allele components
Component
Use(s)
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: varies from orange-brown to nearly wild-type red, depending on site of insertion.

      (Levis et al., 1985)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      wE has phenotype, non-enhanceable by Low1

      (Bhadra et al., 1997)

      wE has phenotype, non-enhanceable by Mowgamma

      (Bhadra and Birchler, 1996)

      wE has phenotype, non-enhanceable by DoaHD

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa3

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa4

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa5

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa6

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa7

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa8

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-enhanceable by Doa9

      (Rabinow and Birchler, 1989)
      Suppressed by
      Statement
      Reference

      wE has phenotype, suppressible by Wowγb

      (Birchler et al., 1994)

      wE has phenotype, suppressible by Wowγe

      (Birchler et al., 1994)

      wE has phenotype, suppressible by Wowems1

      (Birchler et al., 1994)

      wE has phenotype, suppressible by Wowhd1

      (Birchler et al., 1994)
      NOT suppressed by
      Statement
      Reference

      wE has phenotype, non-suppressible by Low1

      (Bhadra et al., 1997)

      wE has phenotype, non-suppressible by Mowgamma

      (Bhadra and Birchler, 1996)

      wE has phenotype, non-suppressible by DoaHD

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa3

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa4

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa5

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa6

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa7

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa8

      (Rabinow and Birchler, 1989)

      wE has phenotype, non-suppressible by Doa9

      (Rabinow and Birchler, 1989)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Protein fails to interact with Ufo1.

      (Bhadra et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      w-1039
      wE
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0060842
      References (6)