FlyBase Allele Report: Dmel\Doa[6]

General Information

Symbol

Dmel\Doa⁶

Species

D. melanogaster

Name

FlyBase ID

FBal0002724

Feature type

allele

Associated gene

Dmel\Doa

Associated Insertion(s)

Carried in Construct

Also Known As

Doa^CC

Key Links

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Rabinow and Birchler, 1989)

Progenitor genotype

Caused by aberration

Tp(3;2)Doa^CC

Cytology

Polytene chromosomes normal.

(Yun et al., 1994)

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Rabinow et al., 1993, Rabinow and Birchler, 1989)

visible | dominant

(Rabinow and Birchler, 1990)

Phenotype Manifest In

Detailed Description

Statement

Reference

In Doa⁶/Doa^E786 mutants where the Doa⁶ allele is from the mother only females are recovered. The flies have rough eyes, duplicated postalar bristles, missing scutellar bristles and disorganisation of the vaginal bristles. When the Doa^E786 allele comes from the mother there are no survivors.

(Kpebe and Rabinow, 2008)

Rare Doa^HD/Doa⁶ escapers of lethality are found at a frequency of approximately 0.5%. Escapers are more frequently female than male (ratio 4:1 ). Male escapers are sterile despite having motile sperm.

(Rabinow and Birchler, 1989)

Heterozygotes with Doa^HD survive rarely and when they do, w^a is darkened to nearly wild-type color; w^sp55 reacts in the opposite manner, becoming nearly white; eyes of escapers have disarranged facets. Males of these heteroallelic combinations involving Doa⁶ are sterile despite having motile sperm; females weakly fertile.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Doa⁶ is an enhancer of phenotype of w^sp55

(Rabinow and Birchler, 1989)

NOT Enhancer of

Statement

Reference

Doa⁶ is a non-enhancer of phenotype of w^a57i11

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^a58l

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^a2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^r

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^IR5

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of y²

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^a3

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^sp81d

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^a59k1

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^sp2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^ec3

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^apl

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^E

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^IR2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^sat

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^bl

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^Bwx

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^a4

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^col

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^e2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^co

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of wⁱ

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^IR3

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^IR4

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^IR6

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^mo

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^IR1

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^h

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^bf2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^zm

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^bf

(Rabinow and Birchler, 1989)

Doa⁶ is a non-enhancer of phenotype of w^e

(Rabinow and Birchler, 1989)

Suppressor of

Statement

Reference

Doa⁶ is a suppressor of phenotype of w^aM

(Rabinow and Birchler, 1989)

Doa⁶ is a suppressor of phenotype of w^aR84h

(Rabinow and Birchler, 1989)

Doa⁶ is a suppressor of phenotype of w^a

(Rabinow and Birchler, 1989)

NOT Suppressor of

Statement

Reference

Doa⁶ is a non-suppressor of phenotype of w^a57i11

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^a58l

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^sp2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^ec3

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^IR2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^bl

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^col

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^e2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^IR4

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^IR6

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^mo

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^Bwx

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^E

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^a3

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^a4

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^apl

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^bf

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^bf2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^co

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^e

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^h

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of wⁱ

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^sat

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^IR3

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^zm

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of y²

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^IR1

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^a2

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^r

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^IR5

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^sp81d

(Rabinow and Birchler, 1989)

Doa⁶ is a non-suppressor of phenotype of w^a59k1

(Rabinow and Birchler, 1989)

Additional Comments

Genetic Interactions

Statement

Reference

Rare Doa^HD/Doa⁶ escapers show extreme suppression of the w^a phenotype, such that eyes, Malpighian tubules, ocelli and testes are essentially wild-type in colour. They have disordered eye facets and scutellar bristles are often missing or abnormal. Male escapers carrying w^sp55 have bleach-white eyes.

(Rabinow and Birchler, 1989)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Does not interact with gypsy induced alleles at several loci (f¹, y² and ct⁶).

(Rabinow and Birchler, 1989)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Doa⁶

Doa^CC

(Kpebe and Rabinow, 2008, Yun et al., 1994, Rabinow et al., 1993, Rabinow and Birchler, 1990, Rabinow and Birchler, 1989)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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