FlyBase Allele Report: Dmel\y[2]

General Information

Symbol

Dmel\y²

Species

D. melanogaster

Name

FlyBase ID

FBal0018612

Feature type

allele

Associated gene

Dmel\y

Associated Insertion(s)

gypsy{}y-2

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Morris et al., 1999, Harrison et al., 1993, Georgiev et al., 1992, Chia et al., 1986)

Progenitor genotype

Associated Insertion(s)

gypsy{}y-2

Cytology

Description

Insertion of gypsy -700bp from the start site.

(Melnikova et al., 2002)

Insertion of a gypsy element between an upstream body cuticle enhancer and a downstream bristle enhancer.

(Cai and Levine, 1997)

Insertion of a gypsy element at -700bp relative to the transcription start site.

(Georgiev et al., 1997)

gypsy insertion into the 5' region of the y gene at position -700bp from the transcription start site.

(Gerasimova et al., 1995)

Insertion of gypsy causes inactivation of certain y enhancers.

(Georgiev and Kozitsina, 1992)

Insertion of gypsy transposable element.

(Geyer and Corces, 1992)

Insertion of gypsy element 700bp upstream from start of transcription.

(Kroczynska et al., 1992)

gypsy insertion 700bp upstream from the transcription initiation site of y.

(Smith and Corces, 1992)

gypsy insertion.

(Georgiev et al., 1990)

Insertion of a gypsy element.

(Georgiev et al., 1990)

Insertion of gypsy element at -700bp from the transcription start site. This separates transcriptional enhancers that control y expression in the wing and body cuticle from the promoter.

(Geyer et al., 1990)

Insertion of gypsy element.

(Georgiev and Gerasimova, 1989)

Insertion of a gypsy element at -700bp.

(Harrison et al., 1989)

gypsy insertion.

(Rabinow and Birchler, 1989)

gypsy insertion 700bp upstream of the transcriptional start site.

(Chia et al., 1986)

gypsy insertion between coordinates +72.4 and +73.7.

(Campuzano et al., 1985)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:355,820..355,823 [+]

(Stow et al., 2022, Matzat et al., 2013, Ong et al., 2013, Ramos et al., 2011, Oliver et al., 2010, Soltani-Bejnood et al., 2007, Capelson and Corces, 2005, Pai et al., 2004, Melnikova et al., 2002, Chen and Corces, 2001, Girard and Freeling, 1999, Golovnin et al., 1999, Soldatov et al., 1999, Zorin et al., 1999, Belenkaya et al., 1998, Morris et al., 1998, Nabirochkin et al., 1998, Cai and Levine, 1997, Gdula and Corces, 1997, Georgiev et al., 1997, Gause et al., 1996, Kim et al., 1996, Gerasimova et al., 1995, Georgiev, 1994, Harrison et al., 1993, Georgiev and Kozitsina, 1992, Geyer and Corces, 1992, Kroczynska et al., 1992, Smith and Corces, 1992, Corces and Geyer, 1991, Georgiev et al., 1990, Georgiev et al., 1990, Geyer et al., 1990, Georgiev and Gerasimova, 1989, Harrison et al., 1989, Rabinow and Birchler, 1989, Campuzano et al., 1986, Chia et al., 1986, Campuzano et al., 1985)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color

(Ou et al., 2009, Golovnin et al., 2008, Soltani-Bejnood et al., 2007, Capelson and Corces, 2006, Drapeau et al., 2006, Lee and Wu, 2006, Capelson and Corces, 2005, Morris et al., 2004, Savitsky et al., 2003, Soldatov et al., 1999, Belenkaya et al., 1998, Chia et al., 1986)

abnormal body color (with y^1#8)

(Savitsky et al., 2003)

abnormal body color (with y^59b)

(Savitsky et al., 2003)

abnormal body color (with y^eve-1)

(Morris et al., 2004)

abnormal body color (with y^eve-tata-1)

(Lee and Wu, 2006)

abnormal body color (with y^eve-tata)

(Lee and Wu, 2006)

abnormal body color (with y^hsp70-1)

(Morris et al., 2004)

abnormal body color (with y^hsp70-tata-1)

(Lee and Wu, 2006)

abnormal body color (with y^inr-1)

(Morris et al., 2004)

abnormal body color (with y^ps1-1)

(Morris et al., 2004)

abnormal body color (with y^ps2-1)

(Morris et al., 2004)

abnormal body color (with y^ps3-1)

(Morris et al., 2004)

abnormal body color (with y^ps4-1)

(Morris et al., 2004)

abnormal body color (with y^tata-1)

(Morris et al., 2004)

abnormal body color (with y^tata)

(Morris et al., 2004)

abnormal body color (with y^tata-inr-1)

(Morris et al., 2004)

abnormal body color (with y^tata-inr)

(Morris et al., 2004)

abnormal body color (with y^TDH-4b)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-28c)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-46)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-55)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-59)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-80)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-98)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-99)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-108)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-116)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-158)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-162)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-163)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-166)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-169)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-172)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-178)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-231)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-244b)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-288)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-321)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-363)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-370)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-376)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-385)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-442)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-470)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-479b)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-490)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-499)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-586)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-641)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-743a)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-743b)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-743c)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-743d)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-786)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-981)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1039)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1061)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1111)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1142)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1491)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1583)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1683)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1872)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-1924)

(Savitsky et al., 2003)

abnormal body color (with y^TDH-2097)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+1)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+36)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+48)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+51)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+105)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+161)

(Savitsky et al., 2003)

abnormal body color (with y^TDH+165)

(Savitsky et al., 2003)

abnormal body color (with y^tT-1)

(Morris et al., 2004)

abnormal body color (with y^TT-1)

(Morris et al., 2004)

abnormal body color (with y^w-1)

(Morris et al., 2004)

abnormal body color (with y^w)

(Morris et al., 2004)

abnormal body color (with y^w-DPE26-1)

(Lee and Wu, 2006)

abnormal body color (with y^w-DPE29-1)

(Lee and Wu, 2006)

abnormal body color (with y^w-DPE29)

(Lee and Wu, 2006)

abnormal body color | recessive

(Mongelard et al., 2002, Zorin et al., 1999, Gause et al., 1998, Gerasimova and Corces, 1998, Georgiev et al., 1997)

visible

(Oliver et al., 2010, Smith and Corces, 1992, Georgiev and Gerasimova, 1989)

visible | recessive

(Mongelard et al., 2002, Gause et al., 1998, Bezborodova et al., 1997, Cai and Levine, 1997, Geyer and Corces, 1992)

Phenotype Manifest In

adult

(Drapeau et al., 2006, Soldatov et al., 1999)

adult abdomen

(Golovnin et al., 2008, Gause et al., 1998)

adult abdomen | male

(Zorin et al., 1999)

adult cuticle

(Oliver et al., 2010, Ou et al., 2009, Soltani-Bejnood et al., 2007, Capelson and Corces, 2006, Lee and Wu, 2006, Capelson and Corces, 2005, Morris et al., 2004, Savitsky et al., 2003, Belenkaya et al., 1998, Bezborodova et al., 1997, Georgiev and Gerasimova, 1989, Chia et al., 1986)

adult cuticle (with y^1#8)

(Savitsky et al., 2003)

adult cuticle (with y^59b)

(Savitsky et al., 2003)

adult cuticle (with y^eve-1)

(Morris et al., 2004)

adult cuticle (with y^eve-tata-1)

(Lee and Wu, 2006)

adult cuticle (with y^eve-tata)

(Lee and Wu, 2006)

adult cuticle (with y^hsp70-1)

(Morris et al., 2004)

adult cuticle (with y^hsp70-tata-1)

(Lee and Wu, 2006)

adult cuticle (with y^inr-1)

(Morris et al., 2004)

adult cuticle (with y^ps1-1)

(Morris et al., 2004)

adult cuticle (with y^ps2-1)

(Morris et al., 2004)

adult cuticle (with y^ps3-1)

(Morris et al., 2004)

adult cuticle (with y^ps4-1)

(Morris et al., 2004)

adult cuticle (with y^tata-1)

(Morris et al., 2004)

adult cuticle (with y^tata)

(Morris et al., 2004)

adult cuticle (with y^tata-inr-1)

(Morris et al., 2004)

adult cuticle (with y^tata-inr)

(Morris et al., 2004)

adult cuticle (with y^TDH-4b)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-28c)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-46)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-55)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-59)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-80)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-98)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-99)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-108)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-116)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-158)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-162)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-163)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-166)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-169)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-172)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-178)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-231)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-244b)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-288)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-321)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-363)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-370)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-376)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-385)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-442)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-470)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-479b)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-490)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-499)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-586)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-641)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-743a)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-743b)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-743c)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-743d)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-786)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-981)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1039)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1061)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1111)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1142)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1491)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1583)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1683)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1872)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-1924)

(Savitsky et al., 2003)

adult cuticle (with y^TDH-2097)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+1)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+36)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+48)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+51)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+105)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+161)

(Savitsky et al., 2003)

adult cuticle (with y^TDH+165)

(Savitsky et al., 2003)

adult cuticle (with y^tT-1)

(Morris et al., 2004)

adult cuticle (with y^TT-1)

(Morris et al., 2004)

adult cuticle (with y^w-1)

(Morris et al., 2004)

adult cuticle (with y^w)

(Morris et al., 2004)

adult cuticle (with y^w-DPE26-1)

(Lee and Wu, 2006)

adult cuticle (with y^w-DPE29-1)

(Lee and Wu, 2006)

adult cuticle (with y^w-DPE29)

(Lee and Wu, 2006)

adult cuticle & wing

(Georgiev et al., 1997)

adult cuticle | male

(Gerasimova and Corces, 1998)

adult epidermis

(Mongelard et al., 2002)

adult thorax

(Gause et al., 1998)

antenna

(Georgiev and Corces, 1995)

cuticle

(Gdula and Corces, 1997, Georgiev and Kozycina, 1996, Gerasimova et al., 1995, Smith and Corces, 1992)

leg & macrochaeta

(Georgiev and Corces, 1995)

macrochaeta

(Gdula and Corces, 1997)

unguis

(Gdula and Corces, 1997)

wing

(Ou et al., 2009, Soltani-Bejnood et al., 2007, Drapeau et al., 2006, Lee and Wu, 2006, Morris et al., 2004, Savitsky et al., 2003, Soldatov et al., 1999, Belenkaya et al., 1998, Gause et al., 1998, Bezborodova et al., 1997, Georgiev and Kozycina, 1996, Gerasimova et al., 1995, Smith and Corces, 1992)

wing (with y^1#8)

(Savitsky et al., 2003)

wing (with y^59b)

(Savitsky et al., 2003)

wing (with y^eve-1)

(Morris et al., 2004)

wing (with y^eve-tata-1)

(Lee and Wu, 2006)

wing (with y^eve-tata)

(Lee and Wu, 2006)

wing (with y^hsp70-1)

(Morris et al., 2004)

wing (with y^hsp70-tata-1)

(Lee and Wu, 2006)

wing (with y^inr-1)

(Morris et al., 2004)

wing (with y^ps1-1)

(Morris et al., 2004)

wing (with y^ps2-1)

(Morris et al., 2004)

wing (with y^ps3-1)

(Morris et al., 2004)

wing (with y^ps4-1)

(Morris et al., 2004)

wing (with y^tata-1)

(Morris et al., 2004)

wing (with y^tata)

(Morris et al., 2004)

wing (with y^tata-inr-1)

(Morris et al., 2004)

wing (with y^tata-inr)

(Morris et al., 2004)

wing (with y^TDH-4b)

(Savitsky et al., 2003)

wing (with y^TDH-28c)

(Savitsky et al., 2003)

wing (with y^TDH-46)

(Savitsky et al., 2003)

wing (with y^TDH-55)

(Savitsky et al., 2003)

wing (with y^TDH-59)

(Savitsky et al., 2003)

wing (with y^TDH-80)

(Savitsky et al., 2003)

wing (with y^TDH-98)

(Savitsky et al., 2003)

wing (with y^TDH-99)

(Savitsky et al., 2003)

wing (with y^TDH-108)

(Savitsky et al., 2003)

wing (with y^TDH-116)

(Savitsky et al., 2003)

wing (with y^TDH-158)

(Savitsky et al., 2003)

wing (with y^TDH-162)

(Savitsky et al., 2003)

wing (with y^TDH-163)

(Savitsky et al., 2003)

wing (with y^TDH-166)

(Savitsky et al., 2003)

wing (with y^TDH-169)

(Savitsky et al., 2003)

wing (with y^TDH-172)

(Savitsky et al., 2003)

wing (with y^TDH-178)

(Savitsky et al., 2003)

wing (with y^TDH-231)

(Savitsky et al., 2003)

wing (with y^TDH-244b)

(Savitsky et al., 2003)

wing (with y^TDH-288)

(Savitsky et al., 2003)

wing (with y^TDH-321)

(Savitsky et al., 2003)

wing (with y^TDH-363)

(Savitsky et al., 2003)

wing (with y^TDH-370)

(Savitsky et al., 2003)

wing (with y^TDH-376)

(Savitsky et al., 2003)

wing (with y^TDH-385)

(Savitsky et al., 2003)

wing (with y^TDH-442)

(Savitsky et al., 2003)

wing (with y^TDH-470)

(Savitsky et al., 2003)

wing (with y^TDH-479b)

(Savitsky et al., 2003)

wing (with y^TDH-490)

(Savitsky et al., 2003)

wing (with y^TDH-499)

(Savitsky et al., 2003)

wing (with y^TDH-586)

(Savitsky et al., 2003)

wing (with y^TDH-641)

(Savitsky et al., 2003)

wing (with y^TDH-743a)

(Savitsky et al., 2003)

wing (with y^TDH-743b)

(Savitsky et al., 2003)

wing (with y^TDH-743c)

(Savitsky et al., 2003)

wing (with y^TDH-743d)

(Savitsky et al., 2003)

wing (with y^TDH-786)

(Savitsky et al., 2003)

wing (with y^TDH-981)

(Savitsky et al., 2003)

wing (with y^TDH-1039)

(Savitsky et al., 2003)

wing (with y^TDH-1061)

(Savitsky et al., 2003)

wing (with y^TDH-1111)

(Savitsky et al., 2003)

wing (with y^TDH-1142)

(Savitsky et al., 2003)

wing (with y^TDH-1491)

(Savitsky et al., 2003)

wing (with y^TDH-1583)

(Savitsky et al., 2003)

wing (with y^TDH-1683)

(Savitsky et al., 2003)

wing (with y^TDH-1872)

(Savitsky et al., 2003)

wing (with y^TDH-1924)

(Savitsky et al., 2003)

wing (with y^TDH-2097)

(Savitsky et al., 2003)

wing (with y^TDH+1)

(Savitsky et al., 2003)

wing (with y^TDH+36)

(Savitsky et al., 2003)

wing (with y^TDH+48)

(Savitsky et al., 2003)

wing (with y^TDH+51)

(Savitsky et al., 2003)

wing (with y^TDH+105)

(Savitsky et al., 2003)

wing (with y^TDH+161)

(Savitsky et al., 2003)

wing (with y^TDH+165)

(Savitsky et al., 2003)

wing (with y^tT-1)

(Morris et al., 2004)

wing (with y^TT-1)

(Morris et al., 2004)

wing (with y^w-1)

(Morris et al., 2004)

wing (with y^w)

(Morris et al., 2004)

wing (with y^w-DPE26-1)

(Lee and Wu, 2006)

wing (with y^w-DPE29-1)

(Lee and Wu, 2006)

wing (with y^w-DPE29)

(Lee and Wu, 2006)

Detailed Description

Statement

Reference

Homozygous females have an almost completely null y[-] pigmentation phenotype in the wings and in the body.

y²/y^1#8 females show nearly wild-type pigmentation levels in the wing and body.

Dp(1;2)y²A reduces the level of complementation that is normally observed between y^1#8 and y² (the progenitor of Dp(1;2)y²A), such that the body and wing cuticle of y^1#8/Dp(1;2)y²A females has a more severe pigmentation phenotype than that of y^1#8/y² females.

Dp(1;4)y²B reduces the level of complementation that is normally observed between y^1#8 and y² (the progenitor of Dp(1;4)y²B), such that the body and wing cuticle of y^1#8/Dp(1;4)y²B females has a more severe pigmentation phenotype than that of y^1#8/y² females.

Dp(1;4)y²C reduces the level of complementation that is normally observed between y^1#8 and y² (the progenitor of Dp(1;4)y²C), such that the body and wing cuticle of y^1#8/Dp(1;4)y²C females has a more severe pigmentation phenotype than that of y^1#8/y² females.

(Ou et al., 2009)

y² flies have a pale abdomen with dark bristles.

(Golovnin et al., 2008)

y² mutants exhibit discoloration of the cuticle, especially apparent in the abdomen.

(Capelson and Corces, 2006)

The male mating success of y² males is statistically equivalent to controls. y² flies have greatly reduced pigmentation throughout their entire body and wings.

(Drapeau et al., 2006)

Body colour: pigmentation score (where 1 = null/nearly null, 5 = wild type/nearly wild type): homozygote: 1 (wing), 1-2 (body), hemizygote: 1 (wing), 1 (body), y²/y^eve-tata : 4 (wing), 4-4⁺ (body), y²/y^hsp70-tata : 5 (wing), 5 (body), y²/y^w-DPE26 : 4-5 (wing), 4⁺-5 (body), y²/y^w-DPE29 : 4 (wing), 4 (body), y²/y^eve-tata-1 : 4 (wing), 3⁺-4 (body), y²/y^hsp70-tata-1 : 1 (wing), 1⁺-2 (body), y²/y^w-DPE26-1 : 1 (wing), 1⁺-2 (body), y²/y^w-DPE29-1 : 3⁺-4 (wing), 3⁺-4 (body).

(Lee and Wu, 2006)

Body colour: pigmentation score (where 1 = null/nearly null, 5 = wild type/nearly wild type): hemizygote: 1 (wing), 1 (body), homozygote: 1 (wing), 1-2 (body), y²/y^tata : 4 (wing), 3 (body), y²/y^inr : 5 (wing), 5 (body), y²/y^tata-inr : 4 (wing), 3-4 (body), y²/y^tata-1 : 3 (wing), 2-3 (body), y²/y^inr-1 : 3 (wing), 2-3 (body), y²/y^tata-inr-1 : 4 (wing), 3-4 (body), y²/y^tT : 5 (wing), 5 (body), y²/y^TT : 5 (wing), 5 (body), y²/y^tT-1 : 1 (wing), 1-2 (body), y²/y^TT-1 : 1 (wing), 1-2 (body), y²/y^ps1 : 5 (wing), 5 (body), y²/y^ps2 : 5 (wing), 5 (body), y²/y^ps3 : 5 (wing), 5 (body), y²/y^ps4 : 5 (wing), 5 (body), y²/y^ps1-1 : 1 (wing), 1-2 (body), y²/y^ps2-1 : 1 (wing), 1-2 (body), y²/y^ps3-1 : 1 (wing), 1-2 (body), y²/y^ps4-1 : 1 (wing), 1-2 (body), y²/y^eve : 5 (wing), 5 (body), y²/y^hsp70 : 5 (wing), 5 (body), y²/y^w : 4 (wing), 4 (body), y²/y^eve-1 : 1 (wing), 1-2 (body), y²/y^hsp70-1 : 1 (wing), 1-2 (body), y²/y^w-1 : 1 (wing), 1-2 (body).

(Morris et al., 2004)

Body colour: flies carrying y² (in a y^- background) have a pigmentation score of 1 (where 1 = absence of y expression and 5

= wild type) in both the body and wing.

Body colour: y²/y^1#8 flies have a pigmentation score of 4 in

both the body and wing.

Body colour: y²/y^59b flies have a pigmentation score of 4 in

both the body and wing.

Body colour: y² in transheterozygous combination with y^TDH+165,

y^TDH+161, y^TDH+105, y^TDH+51, y^TDH+48, y^TDH+36,

y^TDH+1, y^TDH-4b, y^TDH-28c, y^TDH-46, y^TDH-55, y^TDH-59

or y^TDH-80 results in flies with a pigmentation score of 1 in the

wing and 1-2 in the body.

Body colour: y² in transheterozygous combination with y^TDH-98,

y^TDH-99, y^TDH-108 or y^TDH-116 results in flies with a pigmentation

score of 1 in the wing and 1-2 in the body.

Body colour: y² in transheterozygous combination with y^TDH-162,

y^TDH-163, y^TDH-166, y^TDH-169, y^TDH-172, y^TDH-231,

y^TDH-244b, y^TDH-288, y^TDH-321, y^TDH-363, y^TDH-370,

y^TDH-376, y^TDH-385, y^TDH-442, y^TDH-470, y^TDH-479b,

y^TDH-490, y^TDH-499, y^TDH-586, y^TDH-743a, y^TDH-743b,

y^TDH-743c or y^TDH-743d results in flies with a pigmentation

score of 1 in the wing and 1-2 in the body.

Body colour: y² in transheterozygous combination with y^TDH-158,

y^TDH-641 or y^TDH-1039 results in flies with a pigmentation

score of 1 in the wing and 1-2 in the body.

Body colour: y² in transheterozygous combination with y^TDH-178

or y^TDH-786 results in flies with a pigmentation score of 1 in

the wing and 1-2 in the body.

Body colour: y^TDH-981/y² flies have a pigmentation score of

1 in the wing and 1-2 in the body.

Body colour: y^TDH-1061/y² flies have a pigmentation score of

1 in the wing and 1-2 in the body.

Body colour: y^TDH-1111/y² flies have a pigmentation score of

1 in the wing and 1-2 in the body.

Body colour: y^TDH-1142/y² flies have a pigmentation score of

1 in the wing and 1-2 in the body.

Body colour: y^TDH-1491/y² flies have a pigmentation score of

1 in the wing and 3 in the body.

Body colour: y^TDH-1583/y² flies have a pigmentation score of

1 in the wing and 3-4 in the body.

Body colour: y^TDH-1683/y² flies have a pigmentation score of

1 in the wing and 3-4 in the body.

Body colour: y^TDH-1872/y² flies have a pigmentation score of

2 in the wing and 3-4 in the body.

Body colour: y^TDH-1924/y² flies have a pigmentation score of

3 in the wing and 4 in the body.

Body colour: y^TDH-2097/y² flies have a pigmentation score of

4 in the wing and 5 in the body.

Body colour: y^TDH-2491/y² flies have a pigmentation score of

5 in the both the wing and body.

Body colour: y^TDH-2576/y² flies have a pigmentation score of

5 in the both the wing and body.

(Savitsky et al., 2003)

Abdominal pigmentation is lost in the adult.

(Mongelard et al., 2002)

y^tata can support transvection when placed in trans to y²; y²/y^tata flies have a darker wing and body colour than flies homozygous or hemizygous for either y² or y^tata.

(Morris et al., 1999)

Body colour: mutant flies have reduced pigmentation in the body and wings, but wild-type pigmentation in the thoracic, leg and abdominal bristles.

(Soldatov et al., 1999)

Body colour: the abdominal pigment of y² males is lighter than normal, but uniformly distributed in the last two abdominal segments.

(Zorin et al., 1999)

Body colour: pigmentation of the body and wings is reduced, pigmentation of thoracic, leg, wing and abdominal bristles is normal.

(Belenkaya et al., 1998)

Body color score: 1 Wing color score: 1 Thoracic bristle color score: 5 Leg bristle color score: 5 Wing bristle color score: 5 Abdomen bristle color score: 5

(Gause et al., 1998)

Body colour: fifth and sixth abdominal segments brown.

(Gerasimova and Corces, 1998)

Body colour: body yellow; hairs & bristles black.

(Bezborodova et al., 1997, Cai and Levine, 1997)

Body colour: body, wings yellow; hairs & bristles black.

(Georgiev et al., 1997)

The pigmentation induced in unpigmented y² pharate adult tissue by incubation with dopamine in vitro closely resembles the y² phenotype, producing brown pigmentation of cuticle structures, except for black melanin deposition in the bristles.

(Walter et al., 1996)

Body colour: body, wing blade yellow; bristles wild-type. The colouration of the adult cuticular structures shows a variegated pattern. The effect increases at 18^oC and decrease in the presence of extra Y.

(Gerasimova et al., 1995)

Body colour: body, wing yellow; bristles, tarsal claws, wild-type. Larval denticle belt colour: wild-type.

(Geyer and Corces, 1992)

Body colour: body, wing blade yellow; bristles wild-type.

(Smith and Corces, 1992)

Body colour: body, wing blade yellow; wing veins grey; bristles & hairs wild-type.

(Georgiev and Gerasimova, 1989)

Body colour: type 2 allele - some areas of cuticle are wild type, others have mutant pigmentation.

(Chia et al., 1986)

Body colour: body yellow; hairs & bristles black; wing veins grey. Larval mouth part colour: wild-type.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

y² has abnormal body color phenotype, enhanceable by mod(mdg4)^Z3-3401/Df(3R)GC14

(Soltani-Bejnood et al., 2007)

y² has abnormal body color phenotype, enhanceable by Df(3R)GC14/mod(mdg4)^T6

(Soltani-Bejnood et al., 2007)

mod(mdg4)^ul, y² has abnormal body color phenotype, enhanceable by Trl⁶²

(Gerasimova and Corces, 1998)

brm², mod(mdg4)^ul, y² has abnormal body color phenotype, enhanceable by trx^E2

(Gerasimova and Corces, 1998)

y² has visible | recessive phenotype, enhanceable by mod(mdg4)^ul

(Bezborodova et al., 1997)

y² has abnormal body color | recessive phenotype, enhanceable by mod(mdg4)^ul

(Georgiev et al., 1997)

y² has visible | dominant phenotype, enhanceable by mod(mdg4)^ul

(Georgiev and Corces, 1995)

NOT Enhanced by

Statement

Reference

y² has abnormal body color phenotype, non-enhanceable by mod(mdg4)^Z3-5578/mod(mdg4)^T16

(Soltani-Bejnood et al., 2007)

Suppressed by

Statement

Reference

ct⁶, y² has visible | adult stage phenotype, suppressible by HIPP1^UAS.mCh/Scer\GAL4^vg.PM

(Stow et al., 2022)

y² has abnormal body color phenotype, suppressible by Top2^GD4570/Scer\GAL4^arm.PS

(Ramos et al., 2011)

y² has abnormal body color phenotype, suppressible by su(Hw)^GD4493/Scer\GAL4^arm.PS

(Ramos et al., 2011)

y² has visible phenotype, suppressible by Cp190^En15/Cp190^P11

(Oliver et al., 2010)

y² has abnormal body color phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 2008, Capelson and Corces, 2005, Gerasimova and Corces, 1998)

y² has abnormal body color phenotype, suppressible by mod(mdg4)^T6

(Golovnin et al., 2008)

y² has abnormal body color phenotype, suppressible by Df(2R)P34/+

(Capelson and Corces, 2005)

y² has abnormal body color phenotype, suppressible by Topors^RNAi.UAS/Scer\GAL4^Act.PU

(Capelson and Corces, 2005)

y² has abnormal body color | recessive phenotype, suppressible by mod(mdg4)^T6

(Mongelard et al., 2002)

y² has abnormal body color | recessive phenotype, suppressible by mod(mdg4)^ul

(Mongelard et al., 2002)

y² has visible | recessive phenotype, suppressible by mod(mdg4)^T6

(Mongelard et al., 2002)

y² has visible | recessive phenotype, suppressible by mod(mdg4)^ul

(Mongelard et al., 2002)

mod(mdg4)^ul, y² has abnormal body color phenotype, suppressible by lawc^p1

(Zorin et al., 1999)

y² has abnormal body color | recessive phenotype, suppressible by su(Hw)²

(Georgiev et al., 1997)

NOT suppressed by

Statement

Reference

ct⁶, y² has visible | adult stage phenotype, non-suppressible by HIPP1^ΔCLD31.2/HIPP1^ΔCLD14.3

(Stow et al., 2022)

y² has abnormal body color phenotype, non-suppressible by mod(mdg4)^Z3-5578/mod(mdg4)^T16

(Soltani-Bejnood et al., 2007)

e(y)2¹, y² has abnormal body color phenotype, non-suppressible by e(y)2b^su(Hw).PK

(Krasnov et al., 2005)

e(y)2¹, y² has partially lethal | male phenotype, non-suppressible by e(y)2b^su(Hw).PK

(Krasnov et al., 2005)

y² has visible | recessive phenotype, non-suppressible by mod(mdg4)^L3101/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has visible | recessive phenotype, non-suppressible by mod(mdg4)^neo129/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has visible | recessive phenotype, non-suppressible by mod(mdg4)^UASp.cMa/Scer\GAL4^Act5C.PI/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has abnormal body color | recessive phenotype, non-suppressible by mod(mdg4)^L3101/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has abnormal body color | recessive phenotype, non-suppressible by mod(mdg4)^neo129/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has abnormal body color | recessive phenotype, non-suppressible by mod(mdg4)^UASp.cMa/Scer\GAL4^Act5C.PI/mod(mdg4)^ul

(Mongelard et al., 2002)

Other

Statement

Reference

ct⁶, y² has visible | adult stage phenotype

(Stow et al., 2022)

e(y)2¹, y² has abnormal body color phenotype

(Krasnov et al., 2005)

e(y)2¹, y² has partially lethal | male phenotype

(Krasnov et al., 2005)

sc^D1, y²/y^1#8 has visible phenotype

(Gause and Georgiev, 2000)

sc^D1h33, y²/y^1#8 has visible phenotype

(Gause and Georgiev, 2000)

sc^D1, y^59b/y² has visible phenotype

(Gause and Georgiev, 2000)

sc^D1h33, y^59b/y² has visible phenotype

(Gause and Georgiev, 2000)

Taf9¹, y² has abnormal body color phenotype

(Soldatov et al., 1999)

lawc^p1, mod(mdg4)^ul, y² has abnormal body color phenotype

(Zorin et al., 1999)

mod(mdg4)^ul, y² has abnormal body color phenotype

(Zorin et al., 1999)

mod(mdg4)^ul, y² has abnormal body color | recessive phenotype

(Zorin et al., 1999)

lawc^p1, mod(mdg4)^ul, y² has abnormal body color | recessive phenotype

(Zorin et al., 1999)

dvr², y² has visible phenotype

Phenotype Manifest In

Enhanced by

Statement

Reference

y² has phenotype, enhanceable by mod(mdg4)^ul

(Gause et al., 1998, Georgiev and Gerasimova, 1989)

mod(mdg4)^ul, y² has adult cuticle | male phenotype, enhanceable by Trl⁶²

(Gerasimova and Corces, 1998)

brm², mod(mdg4)^ul, y² has adult cuticle | male phenotype, enhanceable by trx^E2

(Gerasimova and Corces, 1998)

y² has adult cuticle phenotype, enhanceable by mod(mdg4)^ul

(Bezborodova et al., 1997)

y² has mesothoracic bristle phenotype, enhanceable by mod(mdg4)^ul

(Cai and Levine, 1997)

y² has phenotype, enhanceable by su(Hw)^ΔA/mod(mdg4)^ul

(Gdula and Corces, 1997)

y² has wing phenotype, enhanceable by mod(mdg4)^ul

(Bezborodova et al., 1997, Georgiev and Kozycina, 1996, Gerasimova et al., 1995)

y² has macrochaeta & leg phenotype, enhanceable by mod(mdg4)^ul

(Georgiev et al., 1997, Georgiev and Kozycina, 1996)

y² has adult cuticle & wing phenotype, enhanceable by mod(mdg4)^ul

(Georgiev et al., 1997)

y² has macrochaeta & adult thorax phenotype, enhanceable by mod(mdg4)^ul

(Georgiev et al., 1997)

y² has wing sensillum phenotype, enhanceable by mod(mdg4)^ul

(Georgiev et al., 1997)

y² has macrochaeta & adult abdomen phenotype, enhanceable by mod(mdg4)^ul

(Georgiev et al., 1997)

y² has cuticle phenotype, enhanceable by mod(mdg4)^ul

(Georgiev and Kozycina, 1996, Gerasimova et al., 1995)

y² has macrochaeta & thorax phenotype, enhanceable by mod(mdg4)^ul

(Georgiev and Kozycina, 1996)

y² has macrochaeta & abdomen phenotype, enhanceable by mod(mdg4)^ul

(Georgiev and Kozycina, 1996)

y² has macrochaeta & wing phenotype, enhanceable by mod(mdg4)^ul

(Georgiev and Kozycina, 1996)

y² has macrochaeta phenotype, enhanceable by mod(mdg4)^ul

(Gerasimova et al., 1995)

y² has unguis phenotype, enhanceable by mod(mdg4)^ul

(Gerasimova et al., 1995)

y² has phenotype, enhanceable by Taf9²

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)2¹

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)3²

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)3³

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)3⁴

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by Taf9^P1

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)6¹

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)6²

(Georgiev and Gerasimova, 1989)

y² has phenotype, enhanceable by e(y)6³

(Georgiev and Gerasimova, 1989)

NOT Enhanced by

Statement

Reference

y² has phenotype, non-enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y² has phenotype, non-enhanceable by su(Hw)^ΔB/mod(mdg4)^ul

(Gdula and Corces, 1997)

y² has phenotype, non-enhanceable by su(Hw)^ΔC/mod(mdg4)^ul

(Gdula and Corces, 1997)

y² has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

y² has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

ct⁶, y² has wing margin phenotype, suppressible by HIPP1^UAS.mCh/Scer\GAL4^vg.PM

(Stow et al., 2022)

mod(mdg4)^T6, y² has adult cuticle phenotype, suppressible | partially by Cp190^En15

(Oliver et al., 2010)

y² has adult cuticle phenotype, suppressible by Cp190^En15/Cp190^P11

(Oliver et al., 2010)

y² has adult abdomen phenotype, suppressible by mod(mdg4)^ul

(Golovnin et al., 2008)

y² has adult abdomen phenotype, suppressible by mod(mdg4)^T6

(Golovnin et al., 2008)

mod(mdg4)^ul, y² has adult cuticle phenotype, suppressible by lwr⁰⁵⁴⁸⁶/Sumo⁰⁴⁴⁹³

(Capelson and Corces, 2006)

mod(mdg4)^ul, y² has adult cuticle phenotype, suppressible by lwr⁰²⁸⁵⁸/Sumo^k06307

(Capelson and Corces, 2006)

y² has adult cuticle phenotype, suppressible by mod(mdg4)^ul

(Capelson and Corces, 2006, Capelson and Corces, 2005)

y² has adult cuticle phenotype, suppressible by Df(2R)P34/+

(Capelson and Corces, 2005)

y² has adult cuticle phenotype, suppressible by Topors^RNAi.UAS/Scer\GAL4^Act.PU

(Capelson and Corces, 2005)

y² has adult epidermis phenotype, suppressible by mod(mdg4)^T6

(Mongelard et al., 2002)

y² has adult epidermis phenotype, suppressible by mod(mdg4)^ul

(Mongelard et al., 2002)

mod(mdg4)^ul, y² has adult abdomen | male phenotype, suppressible by lawc^p1

(Zorin et al., 1999)

y² has phenotype, suppressible by su(Hw)^V

(Belenkaya et al., 1998, Gause et al., 1998, Gerasimova et al., 1995)

y² has adult cuticle | male phenotype, suppressible by mod(mdg4)^ul

(Gerasimova and Corces, 1998)

y² has phenotype, suppressible by su(Hw)²

(Belenkaya et al., 1998, Gause et al., 1998, Georgiev and Kozycina, 1996, Georgiev and Gerasimova, 1989, Lindsley and Grell, 1968)

y² has phenotype, suppressible by su(Hw)^V/su(Hw)^ΔB

(Gdula and Corces, 1997)

y² has phenotype, suppressible by su(Hw)^ΔC/su(Hw)^V

(Gdula and Corces, 1997)

y² has phenotype, suppressible by su(Hw)^ΔCTAD/mod(mdg4)^ul

(Gdula and Corces, 1997)

y² has phenotype, suppressible by su(Hw)^NoAD2/mod(mdg4)^ul

(Gdula and Corces, 1997)

y² has macrochaeta phenotype, suppressible by su(Hw)^ΔB

(Gdula and Corces, 1997)

y² has unguis phenotype, suppressible by su(Hw)^ΔB

(Gdula and Corces, 1997)

y² has cuticle phenotype, suppressible by su(Hw)^ΔB

(Gdula and Corces, 1997)

y² has macrochaeta phenotype, suppressible by su(Hw)^ΔC

(Gdula and Corces, 1997)

y² has unguis phenotype, suppressible by su(Hw)^ΔC

(Gdula and Corces, 1997)

y² has cuticle phenotype, suppressible by su(Hw)^ΔC

(Gdula and Corces, 1997)

y² has adult cuticle & wing phenotype, suppressible by su(Hw)²

(Georgiev et al., 1997)

y² has phenotype, suppressible by su(Hw)⁸

(Georgiev and Kozycina, 1996)

y² has phenotype, suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^Δ706-736

(Kim et al., 1996)

y² has phenotype, suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^Δ853-880

(Kim et al., 1996)

y² has phenotype, suppressible by su(Hw)^Δ673-943/su(Hw)⁷/su(Hw)^V

(Kim et al., 1996)

y² has phenotype, suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^{Δ2-203.673-943}

(Kim et al., 1996)

y² has phenotype, suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^Δ738-780

(Kim et al., 1996)

y² has phenotype, suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^Δ782-944

(Kim et al., 1996)

y² has phenotype, suppressible by su(Hw)^J

(Gerasimova et al., 1995)

y² has phenotype, suppressible by su(Hw)^Δ100

(Gerasimova et al., 1995)

y² has phenotype, suppressible by su(Hw)^Δ283

(Gerasimova et al., 1995)

y² has phenotype, suppressible by su(Hw)^L775K

(Gerasimova et al., 1995)

y² has phenotype, suppressible by su(Hw)^NoAD

(Gerasimova et al., 1995)

y² has phenotype, suppressible by su(Hw)^E8

(Harrison et al., 1993)

y² has phenotype, suppressible by su(Hw)^u1

(Georgiev and Gerasimova, 1989)

y² has phenotype, suppressible by su(Hw)^u2

(Georgiev and Gerasimova, 1989)

NOT suppressed by

Statement

Reference

ct⁶, y² has wing margin phenotype, non-suppressible by HIPP1^ΔCLD31.2/HIPP1^ΔCLD14.3

(Stow et al., 2022)

e(y)2¹, y² has adult head bristle phenotype, non-suppressible by e(y)2b^su(Hw).PK

(Krasnov et al., 2005)

e(y)2¹, y² has chaeta & adult thorax phenotype, non-suppressible by e(y)2b^su(Hw).PK

(Krasnov et al., 2005)

e(y)2¹, y² has tergite phenotype, non-suppressible by e(y)2b^su(Hw).PK

(Krasnov et al., 2005)

y² has adult epidermis phenotype, non-suppressible by mod(mdg4)^L3101/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has adult epidermis phenotype, non-suppressible by mod(mdg4)^neo129/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has adult epidermis phenotype, non-suppressible by mod(mdg4)^UASp.cMa/Scer\GAL4^Act5C.PI/mod(mdg4)^ul

(Mongelard et al., 2002)

y² has phenotype, non-suppressible by Taf9¹/Su(mg)1-6^1-6

(Bezborodova et al., 1997)

y² has phenotype, non-suppressible by Taf9²/Su(mg)1-6^1-6

(Bezborodova et al., 1997)

y² has phenotype, non-suppressible by Taf9¹/Su(mg)1-7^1-7

(Bezborodova et al., 1997)

y² has phenotype, non-suppressible by Taf9²/Su(mg)1-7^1-7

(Bezborodova et al., 1997)

y² has phenotype, non-suppressible by Taf9¹/Su(mg)1-8^1-8

(Bezborodova et al., 1997)

y² has phenotype, non-suppressible by Taf9²/Su(mg)1-8^1-8

(Bezborodova et al., 1997)

y² has phenotype, non-suppressible by su(Hw)^V/su(Hw)^ΔA

(Gdula and Corces, 1997)

y² has phenotype, non-suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^wt

(Kim et al., 1996)

y² has phenotype, non-suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^Δ2-203

(Kim et al., 1996)

y² has phenotype, non-suppressible by su(Hw)⁷/su(Hw)^Δ656-705/su(Hw)^V

(Kim et al., 1996)

y² has phenotype, non-suppressible by su(Hw)⁷/su(Hw)^V/su(Hw)^Δ881-944

(Kim et al., 1996)

y² has phenotype, non-suppressible by su(Hw)^J

(Gerasimova et al., 1995)

y² has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

y² has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

Other

Statement

Reference

ct⁶, y² has wing margin phenotype

(Stow et al., 2022)

mod(mdg4)^T6, y² has abdominal tergite marginal bristle phenotype

(Golovnin et al., 2008)

mod(mdg4)^ul, y² has abdominal tergite marginal bristle phenotype

(Golovnin et al., 2008)

mod(mdg4)^Z3-3401/mod(mdg4)^T16, y² has chaeta phenotype

(Soltani-Bejnood et al., 2007)

mod(mdg4)^T16/mod(mdg4)^T6, y² has chaeta phenotype

(Soltani-Bejnood et al., 2007)

e(y)2¹, y² has adult head bristle phenotype

(Krasnov et al., 2005, Georgiev and Gerasimova, 1989)

e(y)2¹, y² has chaeta & adult thorax phenotype

(Krasnov et al., 2005)

e(y)2¹, y² has tergite phenotype

(Krasnov et al., 2005)

sc^D1, y²/y^1#8 has adult cuticle phenotype

(Gause and Georgiev, 2000)

sc^D1h33, y²/y^1#8 has adult cuticle phenotype

(Gause and Georgiev, 2000)

sc^D1, y^59b/y² has adult cuticle phenotype

(Gause and Georgiev, 2000)

sc^D1h33, y^59b/y² has adult cuticle phenotype

(Gause and Georgiev, 2000)

Taf9¹, y² has adult thorax & macrochaeta phenotype

(Soldatov et al., 1999)

Taf9¹, y² has leg & external sensory organ phenotype

(Soldatov et al., 1999)

lawc^p1, mod(mdg4)^ul, y² has adult abdomen | male phenotype

(Zorin et al., 1999)

mod(mdg4)^ul, y² has adult abdomen | male phenotype

(Zorin et al., 1999)

mod(mdg4)^ul, y² has wing & macrochaeta phenotype

(Bezborodova et al., 1997)

mod(mdg4)^ul, y² has adult thorax & macrochaeta phenotype

(Bezborodova et al., 1997)

mod(mdg4)^ul, y² has adult abdomen & macrochaeta phenotype

(Bezborodova et al., 1997)

mod(mdg4)^ul, y² has leg & macrochaeta phenotype

(Bezborodova et al., 1997)

mod(mdg4)^ul, su(Hw)^ΔA, y² has macrochaeta phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔA, y² has unguis phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has macrochaeta phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has wing phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has unguis phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has abdomen phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^NoAD2, y² has macrochaeta phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^NoAD2, y² has wing phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^NoAD2, y² has unguis phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^NoAD2, y² has abdomen phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔA, y² has wing phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔA, y² has abdomen phenotype

(Gdula and Corces, 1997)

mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has cuticle phenotype

(Gdula and Corces, 1997)

e(y)2¹, y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)2¹, y² has adult thorax & chaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3¹, y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3¹, y² has adult head bristle phenotype

(Georgiev and Gerasimova, 1989)

e(y)3², y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3², y² has adult head bristle phenotype

(Georgiev and Gerasimova, 1989)

e(y)3², y² has adult thorax & chaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3³, y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3³, y² has adult head bristle phenotype

(Georgiev and Gerasimova, 1989)

e(y)3³, y² has adult thorax & chaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3⁴, y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

e(y)3⁴, y² has adult head bristle phenotype

(Georgiev and Gerasimova, 1989)

e(y)3⁴, y² has adult thorax & chaeta phenotype

(Georgiev and Gerasimova, 1989)

Taf9¹, y² has macrochaeta phenotype

(Georgiev and Gerasimova, 1989)

Taf9¹, y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

Taf9¹, y² has adult head bristle phenotype

(Georgiev and Gerasimova, 1989)

Taf9^P1, y² has microchaeta phenotype

(Georgiev and Gerasimova, 1989)

Taf9^P1, y² has adult thorax & chaeta phenotype

(Georgiev and Gerasimova, 1989)

dvr², y² has wing phenotype

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Top2^GD4570 under the control of Scer\GAL4^arm.PS results in a decrease in gypsy insulator function, manifested by a change in body colour from yellow to black in y² mutants.

Expression of su(Hw)^GD4493 under the control of Scer\GAL4^arm.PS results in a decrease in gypsy insulator function, manifested by a change in body colour from yellow to black in y² mutants.

(Ramos et al., 2011)

The cuticle colour of y²; Cp190^En15/Cp190^P11 adults is darker than that of y² flies.

y² Cp190^En15/+, mod(mdg4)^T6 flies have more darkly pigmented body cuticle and wings than y²; mod(mdg4)^T6 flies.

(Oliver et al., 2010)

y² mod(mdg4)^ul double mutant flies have a dappled abdomen with pale bristles.

y² mod(mdg4)^T6 double mutant flies have a dappled abdomen with pale bristles.

(Golovnin et al., 2008)

Body colour: y² ; mod(mdg4)^Z3-3401/mod(mdg4)^T16 and mod(mdg4)^T6/mod(mdg4)^T16 flies have a y^- phenotype (yellow bristles, wings and bodies).

Body colour: the y² phenotype (black bristles, yellow body and wings) is not altered by mod(mdg4)^Z3-5578/mod(mdg4)^T16.

(Soltani-Bejnood et al., 2007)

y² mod(mdg4)^ul double mutants exhibit a suppression of the y² cuticle phenotype, and so exhibit a more pigmented abdomen.

The transheterozygote lwr⁰⁵⁴⁸⁶/smt3⁰⁴⁴⁹³ suppresses the mod(mdg4)^ul suppression of the y² cuticle phenotype, leading to a lighter coloration of the abdomen (due to a reduction in y expression).These phenotypic changes occur in approximately 30% of the mutant flies, with the remaining 70% displaying a continuum of less-pronounced effect. The phenotype is also particularly pronounced in females, although it is detectable in both sexes.

The transheterozygote lwr⁰²⁸⁵⁸/smt3^k06307 suppresses the mod(mdg4)^ul suppression of the y² cuticle phenotype, leading to a lighter coloration of the abdomen (due to a reduction in y expression). These phenotypic changes occur in approximately 30% of the mutant flies, with the remaining 70% displaying a continuum of less-pronounced effect. The phenotype is also particularly pronounced in females, although it is detectable in both sexes.

(Capelson and Corces, 2006)

Body colour: y² ; Df(2R)P34/+ flies show increased production of black pigment in the abdomen compared to y² flies.

Body colour: y² ; mod(mdg4)^ul/+ flies show increased production of black pigment in the abdomen compared to y² flies.

Body colour: y² flies expressing Topors^{dsRNA.Scer\UAS} under the control of Scer\GAL4^Act show increased production of black pigment in the abdomen compared to y² flies.

Body colour: y² ; mod(mdg4)^ul flies that are also expressing Topors^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^Act have a very low level of black pigment in the abdomen.

Body colour: y² ; Lam⁰⁴⁶⁴³/+ ; mod(mdg4)^ul flies show increased production of black pigment in the abdomen compared to y² ; mod(mdg4)^ul flies.

(Capelson and Corces, 2005)

e(y)2¹ y² males show reduced viability compared to wild type. 14% of the mutant males have distorted tergites.

Body colour: e(y)2¹ y² males have reduced pigmentation of head and thorax bristles compared to wild type.

The reduced viability, reduced pigmentation of head and thorax bristles and distorted tergite phenotype that is seen in e(y)2¹ y² males is not rescued by e(y)2b^su(Hw).PK.

(Krasnov et al., 2005)

y² ct⁶; Df(3R)E(mod)4-1^P11/Cp190^H53-2 flies, which are removed from the pupal cases very late in pupal development, display a black cuticle coloration in the abdomen, indicating complete suppression of y². The shape and margins of the wings are normal, indicating complete suppression of ct⁶.

The wings of y² ct⁶; Cp190^H4-1 male flies are rounder in shape, suggesting that ct⁶ is partially suppressed, whereas the bristles are yellow, indicating that the y² phenotype is altered. The body cuticle colour is only slightly darker in the background of the Cp190^H4-1 mutation.

(Pai et al., 2004)

The presence of sc[D1] in y² sc^D1/y^59b flies abolishes interallelic complementation. y² sc^D1/y^59b females show weak pigmentation of the body and wings.

The presence of sc[D1] in y² sc^D1/y^1#8 flies abolishes interallelic complementation. y² sc^D1/y^1#8 females show weak pigmentation of the body and wings.

The presence of sc[D1h33] in y² sc^D1h33/y^1#8 flies abolishes interallelic complementation. y² sc^D1h33/y^1#8 females show weak pigmentation of the body and wings.

The presence of sc[D1h33] in y² sc^D1h33/y^59b flies abolishes interallelic complementation. y² sc^D1h33/y^1#8 females show weak pigmentation of the body and wings.

y² sc^+1MC/y^1#8 females show the same wild-type like pigmentation phenotype as y²/y^1#8 heterozygotes.

y² sc^+1MC/y^59b females show the same wild-type like pigmentation phenotype as y²/y^59b heterozygotes.

y² sc^+2MC/y^1#8 females show the same wild-type like pigmentation phenotype as y²/y^1#8 heterozygotes.

y² sc^+2MC/y^59b females show the same wild-type like pigmentation phenotype as y²/y^59b heterozygotes.

y² sc^R1/y^1#8 females show the same wild-type like pigmentation phenotype as y²/y^1#8 heterozygotes.

y² sc^R1/y^59b females show the same wild-type like pigmentation phenotype as y²/y^59b heterozygotes.

y² sc^R2/y^1#8 females show the same wild-type like pigmentation phenotype as y²/y^1#8 heterozygotes.

y² sc^R2/y^59b females show the same wild-type like pigmentation phenotype as y²/y^59b heterozygotes.

(Gause and Georgiev, 2000)

Pigmentation of the thoracic and leg bristles is reduced in combination with e(y)1¹.

(Soldatov et al., 1999)

y²; mod(mdg4)^ul males have variegated abdominal pigmentation with individual spots of wild-type dark pigment against a lighter pigmented background in the last two abdominal segments. This variegated phenotype is suppressed if the flies are also carrying lawc^p1; the areas of lighter pigmentation increase at the expense of darkly pigmented regions so that the phenotype is closer to y² rather than y² ; mod(mdg4)^ul flies.

(Zorin et al., 1999)

The pigmentation of y²/y^2s11 and y²/y^ds62 flies is unaffected by ph-p^P1. The phenotype is unaffected by ph-p^P1.

(Belenkaya et al., 1998)

su(Hw)^NoAD, su(Hw)^V and su(Hw)^Δ283 suppress the mutant phenotype.

(Gerasimova et al., 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

y^1#8

(Chen et al., 2002)

y^59b

(Gause and Georgiev, 2000)

y^1#8

(Gause and Georgiev, 2000)

y^inr-1

(Morris et al., 1999)

y^tata-1

(Morris et al., 1999)

y^tata-inr-1

(Morris et al., 1999)

y^tata

(Morris et al., 1999)

y^1#8

(Morris et al., 1999)

y²³⁶⁴

(Morris et al., 1999)

y²³⁷⁴

(Morris et al., 1999)

y^59b

(Georgiev and Kozycina, 1996)

y^2PR2

(Georgiev and Kozycina, 1996)

y^2PR1

(Georgiev and Kozycina, 1996)

y^c4

(Geyer et al., 1990)

y^59b

(Geyer et al., 1990)

y^1#8

(Geyer et al., 1990)

y^h12

(Geyer et al., 1990)

y^g

(Geyer et al., 1990)

y⁴¹⁷¹

(Geyer et al., 1990)

y^35a

Partially complements

y^2-269

(Morris et al., 1999)

y^76-2

(Morris et al., 1999)

y^Krasnodar

(Morris et al., 1999)

y^a77

(Morris et al., 1999)

y^cliff

(Morris et al., 1999)

y^zee

(Morris et al., 1999)

y^3c3

(Morris et al., 1999)

y^td

(Morris et al., 1999)

y^c4

(Morris et al., 1999)

y^59b

(Morris et al., 1999)

y²⁵

(Morris et al., 1999)

y^3d

(Morris et al., 1999)

y^2S

(Morris et al., 1999)

y^1#8

(Morris et al., 1999)

y^h12

(Morris et al., 1999)

y^g

(Morris et al., 1999)

y⁴¹⁷¹

(Morris et al., 1999)

y^3c3

(Morris et al., 1998)

y^1#8

(Morris et al., 1998)

y^88d

(Geyer et al., 1990)

Fails to complement

y^TT-1

(Morris et al., 2004)

y^eve-1

(Morris et al., 2004)

y^hsp70-1

(Morris et al., 2004)

y^ps1-1

(Morris et al., 2004)

y^ps2-1

(Morris et al., 2004)

y^ps3-1

(Morris et al., 2004)

y^ps4-1

(Morris et al., 2004)

y^tT-1

(Morris et al., 2004)

y^w-1

(Morris et al., 2004)

y¹

(Chen et al., 2002)

y^1like

(Morris et al., 1999)

y²⁰¹

(Morris et al., 1999)

y^76-1

(Morris et al., 1999)

y^79h

(Morris et al., 1999)

y⁸⁵ⁱ

(Morris et al., 1999)

y^86g30

(Morris et al., 1999)

y^86k1.1

(Morris et al., 1999)

y^Ky

(Morris et al., 1999)

y^RBK

(Morris et al., 1999)

y^m11

(Morris et al., 1999)

y^m15

(Morris et al., 1999)

y^m16

(Morris et al., 1999)

y^m19

(Morris et al., 1999)

y^m1

(Morris et al., 1999)

y^m24

(Morris et al., 1999)

y^m25

(Morris et al., 1999)

y^m27

(Morris et al., 1999)

y^m32

(Morris et al., 1999)

y^m33

(Morris et al., 1999)

y^m36

(Morris et al., 1999)

y^82f29

(Morris et al., 1999)

y^bg

(Morris et al., 1999)

y^62a

(Morris et al., 1999)

y^50k

(Morris et al., 1999)

y^34c

(Morris et al., 1999)

y^31d

(Morris et al., 1999)

y^18CH1

(Morris et al., 1999)

y¹

(Morris et al., 1999)

y⁶⁹

(Morris et al., 1999)

y^A84e61S

(Alexandrov et al., 1985)

y^A84eS

(Alexandrov et al., 1985)

y^A84dS

(Alexandrov et al., 1985)

y^A83fXL

(Alexandrov et al., 1985)

y^A83f26

(Alexandrov et al., 1985)

y^A83f12

(Alexandrov et al., 1985)

y^A82c3

(Alexandrov et al., 1985)

y^A82c2

(Alexandrov et al., 1985)

y^A82c1

(Alexandrov et al., 1985)

y^A81k29

(Alexandrov et al., 1985)

y^A81c3

(Alexandrov et al., 1985)

y^A81c2

(Alexandrov et al., 1985)

y^A81c1

(Alexandrov et al., 1985)

y^A79h1

(Alexandrov et al., 1985)

y^A79g

(Alexandrov et al., 1985)

y^A79d3

(Alexandrov et al., 1985)

y^A79d2

(Alexandrov et al., 1985)

y^A79d

(Alexandrov et al., 1985)

y^A79b21

(Alexandrov et al., 1985)

y^A79b18

(Alexandrov et al., 1985)

y^A78j

(Alexandrov et al., 1985)

y^A77f

(Alexandrov et al., 1985)

y^A77d

(Alexandrov et al., 1985)

y^A76b94

(Alexandrov et al., 1985)

y^A76b37

(Alexandrov et al., 1985)

y^A76a123

(Alexandrov et al., 1985)

y^A76a110

(Alexandrov et al., 1985)

y^A75l2

(Alexandrov et al., 1985)

y^A74e3

(Alexandrov et al., 1985)

y^A74e

(Alexandrov et al., 1985)

y^A74d1

(Alexandrov et al., 1985)

y^A74c166

(Alexandrov et al., 1985)

y^A74c40

(Alexandrov et al., 1985)

y^A74b121

(Alexandrov et al., 1985)

y^A74b51

(Alexandrov et al., 1985)

y^A74b46

(Alexandrov et al., 1985)

y^A72d4

(Alexandrov et al., 1985)

y^A72d3

(Alexandrov et al., 1985)

y^A72d1

(Alexandrov et al., 1985)

y^A72a

(Alexandrov et al., 1985)

y^A71k1

(Alexandrov et al., 1985)

y^A66c

(Alexandrov et al., 1985)

Comments

y²/y^1#8 or y²/y^59b heterozygotes show a practically wild-type body and wing pigmentation phenotype.

(Gause and Georgiev, 2000)

sc¹ y²/y^59b are y²-like in phenotype.

(Geyer et al., 1990)

Images (1)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (4,435)

Bloomington

184

y²

189

y² w^a

36542

y² sc^Hw-Ua

1008

y² dvr¹ v¹

38416

C(1)M3, y²/C(1;Y)1, y¹/0

Kyoto

101259

y²

105780

y² w^a

105777

y² VhaAC39-1^cho-2

101266

y² sc¹ w^sp1

101888

y² w^a ; cn¹

101263

y² sc¹ w^a59k1

107496

C(1)M3, y²/FM7a; Sb¹/TM6

More stocks available...

Notes on Origin

Discoverer

Bridges, 26th Oct. 1925.

Comments

Mutates to y¹-like alleles with X-rays or mutator gene mutations.

y²/Y; mod(mdg4)^ul/+ males derived from mod(mdg4)+ females have a similar phenotype to y²/Y males, y²/Y; mod(mdg4)^ul/+ males derived from mod(mdg4)^ul/mod(mdg4)^ul females have a variegated pigmentation phenotype.

(Gerasimova and Corces, 1998)

See Campuzano et al., Cell 40:327--338 .

(Campuzano et al., 1986)

The ability of various null y alleles to complement the y² phenotype has been studied. The results suggest that where the null y allele can complement the y² phenotype, functional wing and body cuticle enhancers located in the null y allele may be acting in trans on the promoter in the y² allele.

(Geyer et al., 1990)

Promoter causes trans-activation of y¹ enhancer.

(Georgiev and Kozitsina, 1992)

The y² phenotype can be reproduced by transforming y^- flies with a construct carrying a gypsy insert into y. gypsy insertion separates the wing and body tissue-specific enhancers from the y promoter (FBrf0046293).

(Smith and Corces, 1992)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

X04427

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

(Gause and Georgiev, 2000)

y²

(Bag et al., 2022, Melnikova et al., 2019, Melnikova et al., 2017, Matzat et al., 2013, Ong et al., 2013, Ramos et al., 2011, Oliver et al., 2010, Akbari et al., 2009, Ou et al., 2009, Golovnin et al., 2008, Soltani-Bejnood et al., 2007, Capelson and Corces, 2006, Lee and Wu, 2006, Capelson and Corces, 2005, Krasnov et al., 2005, Nikolenko et al., 2005, Pai et al., 2004, Gause and Georgiev, 2000)

Name Synonyms

Secondary FlyBase IDs

References (106)

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