FB2024_03 , released June 25, 2024
Allele: Dmel\su(Hw)8
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General Information
Symbol
Dmel\su(Hw)8
Species
D. melanogaster
Name
FlyBase ID
FBal0016325
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
su(Hw)f3
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

Insertion 0.7kb DNA. Insertion of 0.7kb into the 4.0kb HindIII fragment.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

su(Hw)[+]/su(Hw)8 is an enhancer of visible phenotype of BEAF-32UAS.cYa, Scer\GAL4GMR.PS

Suppressor of
Statement
Reference

su(Hw)8/su(Hw)8 is a suppressor of visible phenotype of ctA

Phenotype Manifest In
Enhancer of
Statement
Reference

su(Hw)[+]/su(Hw)8 is an enhancer of eye phenotype of BEAF-32UAS.cYa, Scer\GAL4GMR.PS

Suppressor of
Statement
Reference

su(Hw)8/su(Hw)8 is a suppressor of wing phenotype of ctA

su(Hw)8/su(Hw)8 is a suppressor of macrochaeta phenotype of fA

su(Hw)8 is a suppressor of phenotype of mod(mdg4)ul

su(Hw)8 is a suppressor of phenotype of y2

su(Hw)8 is a suppressor of wing phenotype of rsP1

su(Hw)8 is a suppressor of wing phenotype of rsP2

Additional Comments
Genetic Interactions
Statement
Reference

su(Hw)8 homozygozity suppresses both the cut-wing defects exhibited by ctA homozygotes and the fork-bristle phenotype exhibited by fA homozygotes.

Partially suppresses y2 and its partial revertants. In combination with mod(mdg4)ul the y2phenotype is completely suppressed. Dominantly suppresses the enhancing effect of mod(mdg4)ul on y2 : increases pigmentation in the body, wings and bristles of the thorax, leg, abdomen and wing. Partially suppresses the scD1 mutant phenotype. Suppression is enhanced by mod(mdg4)ul.

Suppresses oblique truncated wing of rsP1 and rsP2. Effect on rsP1 is recessive. Effect on rsP2 is semidominant. Suppression not temperature-dependent as previously reported (Cramer DIS 55:197 ).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Grell.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (14)