The first Cys residue of zinc finger 10 is changed to Tyr.
Point mutation in one of the Zn fingers which retains some ability to bind DNA.
Point mutation in one of the zinc fingers.
Nucleotide substitution: G2377A. Amino acid replacement: C?Y. Substitution in the tenth zinc finger.
Mutation of one of the zinc fingers.
Southern blot normal.
Point mutation.
G14306189A
G2377A
C525Y | su(Hw)-PA; C525Y | su(Hw)-PB; C525Y | su(Hw)-PC
C?Y
Reported nucleotide numbering from FBrf0048095.
su(Hw)7/Df(3R)su(Hw)-A1933 transheterozygous females are fertile but show loss of the gypsy insulator function (assayed through body, wing and bristle phenotypes induced by mutations in the y, ct and f genes).
P{SUPor-P} induced double strand breakage repair is increased about twofold in a su(Hw)V/su(Hw)7 background compared to wild-type. This phenotype is also seen in flies derived from su(Hw)V/su(Hw)7 parents.
Partial suppression of the y2 phenotype.
su(Hw)2/su(Hw)7 heterozygotes almost completely suppress the "Hw" phenotype acHw-1+R5, extra macrochaetae are seen on the pleura and postnotum. This was accompanied by a 2--3 fold reduction of ac RNA, sc RNA levels were unchanged. A positive correlation can be seen between increased levels of ac transcripts and the appearance of the "Hw" phenotype.
su(Hw)7/su(Hw)E8, wBR.BR has abnormal eye color phenotype, enhanceable by PcZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has abnormal eye color phenotype, enhanceable by ScmZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has abnormal eye color phenotype, enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has abnormal body color phenotype, enhanceable by PcZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, enhanceable by ScmZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, enhanceable by PcZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has abnormal body color phenotype, enhanceable by ScmZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has abnormal body color phenotype, enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has abnormal body color phenotype, non-enhanceable by ScmZnF-ΔSPM.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has abnormal eye color phenotype, non-enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has abnormal eye color phenotype, non-enhanceable by ScmZnF-ΔSPM.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, non-enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, non-enhanceable by ScmZnF-ΔSPM.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has abnormal body color phenotype, non-enhanceable by escZnF.hs.Tag:FLAG
ScmZnF.hs.Tag:FLAG, su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, suppressible by ph-p409
PcZnF.hs.Tag:FLAG, su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, suppressible by ph-p409
escZnF.hs.Tag:FLAG, su(Hw)7/su(Hw)E8, wBR.E.BR has abnormal eye color phenotype, suppressible by ph-p409
su(Hw)7/su(Hw)V is a suppressor of abnormal body color phenotype of yeve-700gin
su(Hw)7/su(Hw)V is a suppressor of abnormal body color phenotype of yw-700gin
su(Hw)7 is a suppressor of abnormal eye color | recessive phenotype of wE.BR.BR
su(Hw)7/su(Hw)V is a non-suppressor of visible phenotype of apP1\loxP.MCP-PRE.MM
In(1)scV2, su(Hw)7/su(Hw)V has abnormal body color phenotype
Df(1)ase-1, su(Hw)7/su(Hw)V has lethal phenotype
su(Hw)7/su(Hw)E8, wBR.BR has pigment cell phenotype, enhanceable by PcZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has pigment cell phenotype, enhanceable by ScmZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has pigment cell phenotype, enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, enhanceable by ScmZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, enhanceable by PcZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has adult cuticle phenotype, enhanceable by ScmZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has adult cuticle phenotype, enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has pigment cell phenotype, non-enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.BR has pigment cell phenotype, non-enhanceable by ScmZnF-ΔSPM.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, non-enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, non-enhanceable by ScmZnF-ΔSPM.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has adult cuticle phenotype, non-enhanceable by escZnF.hs.Tag:FLAG
su(Hw)7/su(Hw)E8, y+mDint2 has adult cuticle phenotype, non-enhanceable by ScmZnF-ΔSPM.hs.Tag:FLAG
ScmZnF.hs.Tag:FLAG, su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, suppressible by ph-p409
PcZnF.hs.Tag:FLAG, su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, suppressible by ph-p409
escZnF.hs.Tag:FLAG, su(Hw)7/su(Hw)E8, wBR.E.BR has pigment cell phenotype, suppressible by ph-p409
su(Hw)7/su(Hw)V is an enhancer of scutellar bristle phenotype of sc5
su(Hw)7/su(Hw)V is an enhancer of scutellar bristle phenotype of sc8
su(Hw)7/su(Hw)V is a non-enhancer of scutellar bristle phenotype of scV2
su(Hw)7/su(Hw)V is a suppressor of anterior notopleural bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor | partially of anterior orbital bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor of anterior supraalar bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor of ocellar bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor of postocellar bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor of presutural bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor of scutellar bristle phenotype of scms1
su(Hw)7/su(Hw)V is a suppressor of anterior notopleural bristle phenotype of scms2
su(Hw)7/su(Hw)V is a suppressor | partially of anterior orbital bristle phenotype of scms2
su(Hw)7/su(Hw)V is a suppressor of anterior supraalar bristle phenotype of scms2
su(Hw)7/su(Hw)V is a suppressor of ocellar bristle phenotype of scms2
su(Hw)7/su(Hw)V is a suppressor of postocellar bristle phenotype of scms2
su(Hw)7/su(Hw)V is a suppressor of presutural bristle phenotype of scms2
su(Hw)7/su(Hw)V is a suppressor of scutellar bristle phenotype of scms2
su(Hw)7, su(Hw)V, su(Hw)Δ706-736 is a suppressor of phenotype of y2
su(Hw)7, su(Hw)V, su(Hw)Δ853-880 is a suppressor of phenotype of y2
su(Hw)Δ673-943, su(Hw)7, su(Hw)V is a suppressor of phenotype of y2
su(Hw)7, su(Hw)V, su(Hw)Δ2-203.673-943 is a suppressor of phenotype of y2
su(Hw)7, su(Hw)V, su(Hw)Δ738-780 is a suppressor of phenotype of y2
su(Hw)7, su(Hw)V, su(Hw)Δ782-944 is a suppressor of phenotype of y2
su(Hw)7 is a suppressor of pigment cell phenotype of wE.BR.BR
su(Hw)7/su(Hw)V is a non-suppressor of wing phenotype of apP1\loxP.MCP-PRE.MM
su(Hw)7/su(Hw)V is a non-suppressor of humeral bristle phenotype of scms1
su(Hw)7/su(Hw)V is a non-suppressor of humeral bristle phenotype of scms2
su(Hw)7, su(Hw)V, su(Hw)Δ2-203 is a non-suppressor of phenotype of y2
su(Hw)7, su(Hw)Δ656-705, su(Hw)V is a non-suppressor of phenotype of y2
su(Hw)7, su(Hw)V, su(Hw)Δ881-944 is a non-suppressor of phenotype of y2
sc5, su(Hw)7/su(Hw)V has ocellar bristle phenotype
scV2, su(Hw)7/su(Hw)V has anterior orbital bristle phenotype
scV2, su(Hw)7/su(Hw)V has presutural bristle phenotype
scV2, su(Hw)7/su(Hw)V has anterior supraalar bristle phenotype
scV2, su(Hw)7/su(Hw)V has anterior notopleural bristle phenotype
scV2, su(Hw)7/su(Hw)V has postocellar bristle phenotype
sc5, su(Hw)7/su(Hw)V has anterior orbital bristle phenotype
sc5, su(Hw)7/su(Hw)V has anterior supraalar bristle phenotype
In(1)scV2, su(Hw)7/su(Hw)V has vertical bristle 1 phenotype
In(1)scV2, su(Hw)7/su(Hw)V has anterior dorsocentral bristle phenotype
In(1)scV2, su(Hw)7/su(Hw)V has posterior dorsocentral bristle phenotype
In(1)scV2, su(Hw)7/su(Hw)V has posterior supraalar bristle phenotype
sc5, su(Hw)7/su(Hw)V has postocellar bristle phenotype
In(1)sc8, su(Hw)7/su(Hw)V has vertical bristle 1 phenotype
In(1)sc8, su(Hw)7/su(Hw)V has anterior dorsocentral bristle phenotype
In(1)sc8, su(Hw)7/su(Hw)V has posterior dorsocentral bristle phenotype
In(1)sc8, su(Hw)7/su(Hw)V has posterior supraalar bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has vertical bristle 1 phenotype
In(1)y3P, su(Hw)7/su(Hw)V has scutellar bristle phenotype
sc8, su(Hw)7/su(Hw)V has humeral bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has humeral bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has ocellar bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has anterior dorsocentral bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has posterior dorsocentral bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has anterior orbital bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has presutural bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has anterior supraalar bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has anterior notopleural bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has postocellar bristle phenotype
In(1)y3P, su(Hw)7/su(Hw)V has posterior supraalar bristle phenotype
sc8, su(Hw)7/su(Hw)V has presutural bristle phenotype
sc8, su(Hw)7/su(Hw)V has anterior supraalar bristle phenotype
scV2, su(Hw)7/su(Hw)V has humeral bristle phenotype
scV2, su(Hw)7/su(Hw)V has ocellar bristle phenotype
wScer\FRT.S.P1\loxP.S flies carrying su(Hw)V/su(Hw)7 tend to have lighter eye pigmentation than wScer\FRT.S.P1\loxP.S flies.
wP1\loxP.S.dW.Scer\FRT.S flies carrying su(Hw)V/su(Hw)7 tend to have darker eye pigmentation than wP1\loxP.S.dW.Scer\FRT.S flies.
wΔS.dW.Scer\FRT.S flies carrying su(Hw)V/su(Hw)7 tend to have lighter eye pigmentation than wΔS.dW.Scer\FRT.S flies.
Body colour: flies carrying yEye125bpYSW.Scer\FRT.P1\loxP (in a y- background) have wild-type levels of pigmentation if they are also carrying su(Hw)V/su(Hw)7. In(1)y3P ; su(Hw)V/su(Hw)7 animals show loss of a number of bristles. Bristle pigmentation is normal in these animals. In(1)scV2 ; su(Hw)V/su(Hw)7 animals show loss of a number of bristles. Bristle pigmentation shows mild variegation in these animals; about half the bristles are yellow. In(1)sc8 ; su(Hw)V/su(Hw)7 animals show loss of a number of bristles. Bristle pigmentation is normal in these animals. sc5 ; su(Hw)V/su(Hw)7 animals show loss of a number of bristles. Bristle pigmentation is normal in these animals.
Pigmentation of y1/y1; yP1\loxP.su(Hw)BR-y-AS-C.-900 animals is largely unaffected by a su(Hw)7/Df(3R)su(Hw)V background.
In a su(Hw)V/su(Hw)7 background, the adbdominal phenotype of Abd-BFab7-2.gypsy\su(Hw)BR-340/+ males reverts to that seen in Fab-72 flies.
Neither su(Hw)A2663 nor su(Hw)A460 complements su(Hw)7, a separation-of-function alleles that only affects the gypsy insulator function (assayed through body, wing and bristle phenotypes induced by mutations in the y, ct and f genes), this allele is complemented by su(Hw)M393 (a separation-of-function allele that impairs female fertility).
Grell.
Arose on: In(3LR)TM6.