FB2024_03 , released June 25, 2024
Allele: Dmel\su(Hw)ΔCTAD
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General Information
Symbol
Dmel\su(Hw)ΔCTAD
Species
D. melanogaster
Name
FlyBase ID
FBal0056044
Feature type
allele
Associated gene
Dmel\su(Hw)
Associated Insertion(s)
Carried in Construct
P{su(Hw)ΔCTAD}
Key Links
Transgenic product class
stop_gained
(Gdula and Corces, 1997)
Mutagen
Nature of the Allele
Transgenic product class
stop_gained
(Gdula and Corces, 1997)
Mutagen
in vitro construct
(Gdula and Corces, 1997)
Progenitor genotype
su(Hw)+t5.2
(Gdula and Corces, 1997)
Carried in construct
P{su(Hw)ΔCTAD}
Cytology
Description

A stop codon has been introduced at position 861, effectively producing a deletion of the carboxy-terminal acidic domain.

(Gdula and Corces, 1997)
Allele components
Component
Use(s)
Regulatory region(s)
su(Hw)
Encoded product / tool
su(Hw)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Shows complete repression of the y body and wing enhancers. When crossed into a y2, mod(mdg4)ul mutant background the flies display bristle, tarsal claws, abdomen and wings with a coloration between null mutant and wild type.

      (Gdula and Corces, 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Mutant protein completely represses y distal enhancer function.

      (Gdula and Corces, 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      su(Hw)ΔCTAD
      Name Synonyms
      Secondary FlyBase IDs
        References (2)