FlyBase Allele Report: Dmel\sc[D1]

General Information

Symbol

Dmel\sc^D1

Species

D. melanogaster

Name

of Dobzhansky

FlyBase ID

FBal0015230

Feature type

allele

Associated gene

Dmel\sc

Associated Insertion(s)

gypsy{}sc-D1

jockey{}sc-D1

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Lindsley and Zimm, 1992)

Progenitor genotype

Associated Insertion(s)

gypsy{}sc-D1

jockey{}sc-D1

Cytology

Polytene chromosomes apparently normal (Schultz).

(Lindsley and Zimm, 1992)

Description

Insertion of a gypsy element and a jockey element downstream of sc. The jockey element maps 1.8kb from the gypsy.

(Gause et al., 1996)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Golovnin et al., 1999, Mari-Beffa et al., 1991)

visible | recessive

(Bezborodova et al., 1997)

Phenotype Manifest In

Detailed Description

Statement

Reference

More than 90% of flies lack the anterior notopleural, postvertical, ocellar, scutellar and anterior orbital bristles. The humeral, presutural, anterior postalar, anterior supraalar, posterior postalar and posterior supraalar bristles are present.

(Golovnin et al., 1999)

More than 90% of sc^D1 flies lack the anterior orbital, post-vertical, ocellar and anterior notopleural bristles. The flies have one scutellar bristle.

(Bezborodova et al., 1997)

Anterior notopleural bristle formation is blocked.

(Gause et al., 1996)

Phenotype can be suppressed by strong su(Hw) alleles, or weak su(Hw) alleles in combination with mod(mdg4)^ul. mod(mdg4)^ul has a partial suppressing effect alone.

(Georgiev and Kozycina, 1996)

Weak sc. RK2.

(Lindsley and Zimm, 1992)

Homozygous females show a loss of tergite chaetae.

(Mari-Beffa et al., 1991)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

sc^D1 has visible phenotype, enhanceable by Df(1)sc19

(Mari-Beffa et al., 1991)

sc^D1 has visible phenotype, enhanceable by Df(1)260-1

(Mari-Beffa et al., 1991)

Suppressed by

Statement

Reference

mod(mdg4)^ul, sc^D1 has visible | recessive phenotype, suppressible by Su(mg)1-7^1-7

(Bezborodova et al., 1997)

sc^D1 has visible | recessive phenotype, suppressible by mod(mdg4)^ul

(Bezborodova et al., 1997)

Other

Statement

Reference

sc^D1, y²/y^1#8 has visible phenotype

(Gause and Georgiev, 2000)

sc^D1, y^59b/y² has visible phenotype

(Gause and Georgiev, 2000)

Phenotype Manifest In

Enhanced by

Statement

Reference

sc^D1 has chaeta phenotype, enhanceable by Df(1)sc19

(Mari-Beffa et al., 1991)

sc^D1 has tergite phenotype, enhanceable by Df(1)sc19

(Mari-Beffa et al., 1991)

sc^D1 has chaeta phenotype, enhanceable by Df(1)260-1

(Mari-Beffa et al., 1991)

sc^D1 has tergite phenotype, enhanceable by Df(1)260-1

(Mari-Beffa et al., 1991)

Suppressed by

Statement

Reference

sc^D1 has anterior orbital bristle phenotype, suppressible by mod(mdg4)^ul

(Bezborodova et al., 1997)

sc^D1 has postocellar bristle phenotype, suppressible by mod(mdg4)^ul

(Bezborodova et al., 1997)

sc^D1 has ocellar bristle phenotype, suppressible by mod(mdg4)^ul

(Bezborodova et al., 1997)

sc^D1 has scutellar bristle phenotype, suppressible by z^v77h

(Gause et al., 1996)

sc^D1 has macrochaeta & scutum phenotype, suppressible by z^v77h

(Gause et al., 1996)

sc^D1 has phenotype, suppressible by Taf9¹

(Gause et al., 1996)

sc^D1 has phenotype, suppressible by e(y)3⁴

(Gause et al., 1996)

sc^D1 has anterior notopleural bristle phenotype, suppressible by z^v77h

(Gause et al., 1996)

sc^D1 has ocellar bristle phenotype, suppressible by z^v77h

(Gause et al., 1996)

sc^D1 has postocellar bristle phenotype, suppressible by z^v77h

(Gause et al., 1996)

sc^D1 has phenotype, suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Other

Statement

Reference

sc^D1, y²/y^1#8 has adult cuticle phenotype

(Gause and Georgiev, 2000)

sc^D1, y^59b/y² has adult cuticle phenotype

(Gause and Georgiev, 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The presence of sc[D1] in y² sc^D1/y^59b flies abolishes interallelic complementation. y² sc^D1/y^59b females show weak pigmentation of the body and wings.

The presence of sc[D1] in y² sc^D1/y^1#8 flies abolishes interallelic complementation. y² sc^D1/y^1#8 females show weak pigmentation of the body and wings.

(Gause and Georgiev, 2000)

The sc^D1 bristle phenotype is partially suppressed by mod(mdg4)^ul.

(Bezborodova et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Dobzhansky, 1930.

(Lindsley and Zimm, 1992)

Induced with: y^D1.

(Lindsley and Zimm, 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

sc¹

(Gause and Georgiev, 2000)

sc^D1

(Golovnin et al., 2008, Golovnin et al., 2008, Gause and Georgiev, 2000, Mari-Beffa et al., 1991)

scD1

(Gause and Georgiev, 2000)

Name Synonyms

of Dobzhansky

Secondary FlyBase IDs

References (16)

Report Sections

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