Insertion of a 1.2kb P-element into the untranslated leader sequence at 109bp (coordinate according to the cDNA clone map described in FBrf0054014). The P-element is transcribed in the same orientation as ph-p. Sequences between 829bp and 2560bp of the P-element are deleted, with the filler sequence TAGCTACAAA inserted at the breakpoint.
Insertion of 1.2 kb P-element into the 5' transcribed non-translated region.
ph-pP1, y2s7 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y2s7 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y+sA22 has abnormal body color phenotype, suppressible | partially by sneP1
ph-pP1, y+sA22 has abnormal body color phenotype, suppressible | partially by Su(y)P22P22/Su(y)P22[+]
ph-pP1, y+sA22 has abnormal body color phenotype, suppressible | partially by Su(y)P31[+]/Su(y)P31P31
ph-pP1, y+sA8 has abnormal body color phenotype, suppressible | partially by sneP1
ph-pP1, y+sA8 has abnormal body color phenotype, suppressible | partially by Su(y)P22P22/Su(y)P22[+]
ph-pP1, y+sA8 has abnormal body color phenotype, suppressible | partially by Su(y)P31[+]/Su(y)P31P31
ph-pP1, y+s has abnormal body color | recessive phenotype, suppressible by sneP1/sn[+]
ph-pP1, y+s has abnormal body color | recessive phenotype, suppressible by Su(y)P22P22/Su(y)P22[+]
ph-pP1, y+s has abnormal body color | recessive phenotype, suppressible by Su(y)P31[+]/Su(y)P31P31
ph-pP1, y+s has abnormal body color phenotype, suppressible by su(Hw)2
ph-pP1, y+s has abnormal body color phenotype, suppressible by su(Hw)V
ph-pP1, y2s26 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y2s26 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y2s16 has abnormal body color phenotype, suppressible by su(Hw)2
ph-pP1, y2s16 has abnormal body color phenotype, suppressible by su(Hw)V
ph-pP1, y2s11 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y2s11 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y+sA12 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y+sA12 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y+s32 has abnormal body color phenotype, suppressible by su(Hw)2
ph-pP1, y+s32 has abnormal body color phenotype, suppressible by su(Hw)V
ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by sneP1/sn[+]
ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by Su(y)P22P22/Su(y)P22[+]
ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by Su(y)P31[+]/Su(y)P31P31
ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y2s25 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y2s25 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y+sA11 has abnormal body color phenotype, suppressible | partially by su(Hw)2
ph-pP1, y+sA11 has abnormal body color phenotype, suppressible | partially by su(Hw)V
ph-pP1, y2s14 has abnormal body color phenotype, suppressible by sneP1
ph-pP1, y2s14 has abnormal body color phenotype, suppressible by Su(y)P22P22/Su(y)P22[+]
ph-pP1, y2s14 has abnormal body color phenotype, suppressible by Su(y)P31[+]/Su(y)P31P31
ph-pP1, y2s14 has abnormal body color phenotype, suppressible | partially by snwP13
ph-pP1, y2s14 has abnormal body color phenotype, suppressible | partially by snwP14
ph-pP1, y2s14 has abnormal body color phenotype, suppressible by su(Hw)2
ph-pP1, y2s14 has abnormal body color phenotype, suppressible by su(Hw)V
Taf9P1, ph-pP1 has lethal | embryonic stage phenotype, suppressible by Taf9+tSa
ph-pP1, y2s7 has abnormal body color phenotype, non-suppressible by sneP1
ph-pP1, y2s7 has abnormal body color phenotype, non-suppressible by Su(y)P22P22
ph-pP1, y2s25 has abnormal body color phenotype, non-suppressible by Su(y)P22P22
ph-pP1, y2s25 has abnormal body color phenotype, non-suppressible by Su(y)P31P31
ph-pP1, y2s14 has abnormal body color phenotype, non-suppressible by sn+P11
ph-pP1, y2s14 has abnormal body color phenotype, non-suppressible by sn+P12
ph-pP1, y2s7 has abnormal body color phenotype, non-suppressible by Su(y)P31P31
ph-pP1, y2s26 has abnormal body color phenotype, non-suppressible by sneP1
ph-pP1, y2s26 has abnormal body color phenotype, non-suppressible by Su(y)P22P22
ph-pP1, y2s26 has abnormal body color phenotype, non-suppressible by Su(y)P31P31
ph-pP1, y2s11 has abnormal body color phenotype, non-suppressible by sneP1
ph-pP1, y2s11 has abnormal body color phenotype, non-suppressible by Su(y)P22P22
ph-pP1, y2s11 has abnormal body color phenotype, non-suppressible by Su(y)P31P31
ph-pP1, y2s25 has abnormal body color phenotype, non-suppressible by sneP1
ph-pP1 is an enhancer of abnormal body color phenotype of y2s14
ph-pP1 is an enhancer of abnormal body color | recessive phenotype of y+s
ph-pP1 is an enhancer of abnormal body color phenotype of y2s26
ph-pP1 is an enhancer of abnormal body color phenotype of y2s7
ph-pP1 is an enhancer of abnormal body color phenotype of y2s10-2
ph-pP1 is an enhancer of abnormal body color phenotype of y2s16
ph-pP1 is an enhancer of abnormal body color phenotype of y2s11
ph-pP1 is an enhancer of abnormal body color phenotype of y2s2
ph-pP1 is an enhancer of abnormal body color phenotype of y+sA12
ph-pP1 is an enhancer of abnormal body color phenotype of y+s32
ph-pP1 is an enhancer of abnormal eye color phenotype of wΔP
ph-pP1 is an enhancer of abnormal body color phenotype of y+s22
ph-pP1 is an enhancer of abnormal body color phenotype of y2s25
ph-pP1 is an enhancer of abnormal body color phenotype of y+sA11
ph-pP1 is an enhancer of abnormal body color phenotype of yΔP.tBa
ph-pP1 is an enhancer of abnormal body color phenotype of y2s42
ph-pP1 is an enhancer of abnormal body color phenotype of yds62
ph-pP1 is an enhancer of abnormal body color phenotype of y2s20
ph-pP1 is an enhancer of abnormal body color phenotype of y2sA3
ph-pP1 is an enhancer of abnormal body color phenotype of y76d28
Trf2P1, ph-pP1 has lethal | larval stage phenotype
Trf2P1, ph-pP1 has lethal | pupal stage phenotype
Trf2P1, ph-pP1 has lethal | embryonic stage phenotype
Trf2P1, ph-pP1 has female sterile phenotype
Trf2P1, ph-pP1 has short lived phenotype
Trf2P1, ph-pP1 has male sterile | partially phenotype
Trf2P1, ph-pP1 has male semi-sterile phenotype
ph-pP1, y+sA22 has abnormal body color phenotype
ph-pP1, y+sA8 has abnormal body color phenotype
Taf9P1, ph-pP1 has lethal | embryonic stage phenotype
ph-pP1, y+s8 has abnormal body color phenotype
ph-pP1, y+s7 has abnormal body color phenotype
ph-pP1 is an enhancer of tarsal segment | ectopic phenotype of Trf2P1
ph-pP1 is an enhancer of leg sensillum phenotype of y2s14
ph-pP1 is an enhancer of wing sensillum phenotype of y2s14
ph-pP1 is an enhancer of leg sensillum phenotype of y+s
ph-pP1 is an enhancer of leg sensillum phenotype of y2s26
ph-pP1 is an enhancer of wing sensillum phenotype of y2s26
ph-pP1 is an enhancer of leg sensillum phenotype of y2s10-2
ph-pP1 is an enhancer of wing sensillum phenotype of y2s10-2
ph-pP1 is an enhancer of leg sensillum phenotype of y2s16
ph-pP1 is an enhancer of wing sensillum phenotype of y2s16
ph-pP1 is an enhancer of leg sensillum phenotype of y2s11
ph-pP1 is an enhancer of wing sensillum phenotype of y2s11
ph-pP1 is an enhancer of leg sensillum phenotype of y2s2
ph-pP1 is an enhancer of wing sensillum phenotype of y2s2
ph-pP1 is an enhancer of leg sensillum phenotype of y2s7
ph-pP1 is an enhancer of leg sensillum phenotype of y+sA12
ph-pP1 is an enhancer of wing sensillum phenotype of y+sA12
ph-pP1 is an enhancer of leg sensillum phenotype of y+s32
ph-pP1 is an enhancer of wing sensillum phenotype of y2s7
ph-pP1 is an enhancer of pigment cell phenotype of wΔP
ph-pP1 is an enhancer of leg sensillum phenotype of y+s22
ph-pP1 is an enhancer of wing sensillum phenotype of y+s22
ph-pP1 is an enhancer of leg sensillum phenotype of y2s25
ph-pP1 is an enhancer of wing sensillum phenotype of y2s25
ph-pP1 is an enhancer of leg sensillum phenotype of y+sA11
ph-pP1 is an enhancer of wing sensillum phenotype of y+sA11
ph-pP1 is an enhancer of macrochaeta phenotype of yΔP.tBa
ph-pP1 is an enhancer of leg sensillum phenotype of y2s42
ph-pP1 is an enhancer of adult cuticle phenotype of y2s7
ph-pP1 is an enhancer of prothoracic leg sensillum phenotype of y76d28
ph-pP1 is an enhancer of mesothoracic leg sensillum phenotype of y76d28
ph-pP1 is an enhancer of metathoracic leg sensillum phenotype of y76d28
ph-pP1 is an enhancer of adult abdominal sensillum phenotype of y76d28
ph-pP1 is an enhancer of adult cuticle phenotype of yds62
ph-pP1 is an enhancer of adult cuticle phenotype of y2s11
ph-pP1 is an enhancer of adult cuticle phenotype of y76d28
ph-pP1 is an enhancer of wing sensillum phenotype of y76d28
Trf2P1, ph-pP1 has presumptive embryonic/larval peripheral nervous system phenotype
Trf2P1, ph-pP1 has presumptive embryonic/larval central nervous system phenotype
Trf2P1, ph-pP1 has spermatocyte phenotype
Trf2P1, ph-pP1 has egg chamber phenotype
Trf2P1, ph-pP1 has embryonic segment phenotype
Trf2P1, ph-pP1 has primary spermatocyte phenotype
ph-pP1, y+s8 has prothoracic leg sensillum phenotype
ph-pP1, y+s8 has mesothoracic leg sensillum phenotype
ph-pP1, y+s8 has metathoracic leg sensillum phenotype
ph-pP1, y2s11 has wing sensillum phenotype
ph-pP1, y2s11 has prothoracic leg sensillum phenotype
ph-pP1, y2s11 has mesothoracic leg sensillum phenotype
ph-pP1, y2s11 has metathoracic leg sensillum phenotype
ph-pP1, y2s11 has adult abdominal sensillum phenotype
ph-pP1, y+s7 has adult cuticle phenotype
ph-pP1, y2s14 has wing sensillum phenotype
ph-pP1, y2s14 has prothoracic leg sensillum phenotype
ph-pP1, y2s14 has mesothoracic leg sensillum phenotype
ph-pP1, y2s14 has metathoracic leg sensillum phenotype
ph-pP1, y2s14 has adult abdominal sensillum phenotype
ph-pP1, y2s20 has wing sensillum phenotype
ph-pP1, y2s20 has prothoracic leg sensillum phenotype
ph-pP1, y2s20 has mesothoracic leg sensillum phenotype
ph-pP1, y2s20 has metathoracic leg sensillum phenotype
ph-pP1, y2s20 has adult abdominal sensillum phenotype
ph-pP1, y2s7 has wing sensillum phenotype
ph-pP1, y2s7 has prothoracic leg sensillum phenotype
ph-pP1, y2s7 has mesothoracic leg sensillum phenotype
ph-pP1, y2s7 has metathoracic leg sensillum phenotype
ph-pP1, y2s7 has adult abdominal sensillum phenotype
ph-pP1, y2sA3 has wing sensillum phenotype
ph-pP1, y+s7 has prothoracic leg sensillum phenotype
ph-pP1, y2sA3 has prothoracic leg sensillum phenotype
ph-pP1, y2sA3 has mesothoracic leg sensillum phenotype
ph-pP1, y2sA3 has metathoracic leg sensillum phenotype
ph-pP1, y2sA3 has adult abdominal sensillum phenotype
ph-pP1, yds62 has wing sensillum phenotype
ph-pP1, yds62 has prothoracic leg sensillum phenotype
ph-pP1, yds62 has mesothoracic leg sensillum phenotype
ph-pP1, yds62 has metathoracic leg sensillum phenotype
ph-pP1, yds62 has adult abdominal sensillum phenotype
ph-pP1, y+s7 has mesothoracic leg sensillum phenotype
ph-pP1, y+s7 has metathoracic leg sensillum phenotype
ph-pP1, y+s8 has adult cuticle phenotype
The viability of ph-pP1 Trf2P1 double mutants is strongly decreased. Mortality is seen at the late embryonic stage (approximately 50%) and larval and pupal stages (approximately 30%). Approximately 10% of double hemizygous males and 1% of double homozygous females survive to adulthood. The adults die in 5 to 10 days after eclosion. The double homozygous females are completely sterile and the double hemizygous males have decreased fertility. Approximately 30% of the adults have an extreme transformation of arista to tarsus. The adults have shortened bodies.
Approximately 10% of ph-pP1 Trf2P1 double mutant embryos have defects in central nervous system development, and approximately 20% of the mutant embryos have defects in the ventral and lateral clusters of the embryonic peripheral nervous system. Defects in segment organisation are seen in approximately 15% of the embryos.
The karyosome often appears more diffuse than normal in ph-pP1 Trf2P1 double mutant oocytes. ph-pP1 Trf2P1 double mutant ovaries contain few mature oocytes and have abnormally shaped egg chambers. The ovarioles often contain several follicles that have not separated from the germarium. Many egg chambers contain more than the normal number of 16 nuclei, representing joint cysts packaged inside a monolayer of follicle cells.
ph-pP1 Trf2P1 double mutant males have thinner testes than wild-type males. No abnormalities are seen in young primary spermatocytes, but at later stages, many primary spermatocytes show differentiation defects; the chromosome bivalents look more diffuse during metaphase, and aberrant spindles are seen. A significant number of cysts in the mutant testis contain abnormal mature spermatocytes that are probably necrotic.
Mutation encodes a chimeric P-element-ph-p protein, consisting of the DNA binding domain of the P-element and theph-pPh protein lacking 12 amino-terminal amino acids.