FB2024_03 , released June 25, 2024
Allele: Dmel\y+s22
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General Information
Symbol
Dmel\y+s22
Species
D. melanogaster
Name
FlyBase ID
FBal0062348
Feature type
allele
Associated gene
Dmel\y
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    y+s
    (Georgiev et al., 1997)
    Caused by aberration
    Tp(1;1)y+s22
    Cytology
    Description

    The genomic DNA fragment located between the P-elements in the insertion present in y+s has been inverted.

    (Georgiev et al., 1997)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Body colour: flies have wild-type pigmentation in the body cuticle and wing blade and in the thoracic, leg, wing and abdominal bristles.

        (Biryukova et al., 1999)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Statement
        Reference

        y+s22 has abnormal body color phenotype, enhanceable by ph-pP1

        (Biryukova et al., 1999)
        Suppressed by
        Statement
        Reference

        ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by sneP1/sn[+]

        (Biryukova et al., 1999)

        ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by Su(y)P22P22/Su(y)P22[+]

        (Biryukova et al., 1999)

        ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by Su(y)P31[+]/Su(y)P31P31

        (Biryukova et al., 1999)

        ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by su(Hw)2

        (Biryukova et al., 1999)

        ph-pP1, y+s22 has abnormal body color phenotype, suppressible | partially by su(Hw)V

        (Biryukova et al., 1999)
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        y+s22 has wing phenotype, enhanceable by ph-pP1

        (Biryukova et al., 1999)

        y+s22 has adult thorax & macrochaeta phenotype, enhanceable by ph-pP1

        (Biryukova et al., 1999)

        y+s22 has leg sensillum phenotype, enhanceable by ph-pP1

        (Biryukova et al., 1999)

        y+s22 has wing sensillum phenotype, enhanceable by ph-pP1

        (Biryukova et al., 1999)

        y+s22 has adult abdomen & macrochaeta phenotype, enhanceable by ph-pP1

        (Biryukova et al., 1999)
        NOT Enhanced by
        Statement
        Reference

        y+s22 has phenotype, non-enhanceable by su(Hw)2

        (Georgiev et al., 1997)

        y+s22 has phenotype, non-enhanceable by mod(mdg4)ul

        (Georgiev et al., 1997)
        NOT suppressed by
        Statement
        Reference

        y+s22 has phenotype, non-suppressible by su(Hw)2

        (Georgiev et al., 1997)

        y+s22 has phenotype, non-suppressible by mod(mdg4)ul

        (Georgiev et al., 1997)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        In the presence of ph-pP1, pigmentation is very strongly reduced in y+s22 flies. This enhancement by ph-pP1 is partially suppressed by su(Hw)2/su(Hw)V.

        (Biryukova et al., 1999)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        y+s22
        Name Synonyms
        Secondary FlyBase IDs
          References (2)