FlyBase Allele Report: Dmel\y[76d28]

General Information

Symbol

Dmel\y^76d28

Species

D. melanogaster

Name

FlyBase ID

FBal0018651

Feature type

allele

Associated gene

Dmel\y

Associated Insertion(s)

P{}y^76d28

Carried in Construct

Key Links

Allele class

Mutagen

PM hybrid dysgenesis

Nature of the Allele

Allele class

Mutagen

PM hybrid dysgenesis

Progenitor genotype

Associated Insertion(s)

P{}y^76d28

Cytology

Description

Insertion of 1.1kb P-element in the 5' untranslated region, in the opposite transcriptional orientation to the y gene. The P-element is the same size, and is inserted in the same position as y^1#7, but the P-element is in opposite orientation relative to the y gene in the two alleles.

(Geyer et al., 1991)

Insertion of a P-element into y at +76bp (in the transcribed untranslated region). The P-element is inserted in the opposite orientation to that in y^1#7.

(Geyer et al., 1990)

Insertion of a 1.1kb P-element integrated 76bp downstream from the mRNA cap site in the 5' transcribed, untranslated portion of the y gene, in the opposite orientation to the transcription of y.

(Geyer et al., 1988)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color

(Soldatov et al., 1999, Belenkaya et al., 1998, Geyer et al., 1990, Geyer et al., 1988)

Phenotype Manifest In

adult

(Soldatov et al., 1999)

adult abdomen & macrochaeta

(Soldatov et al., 1999)

adult abdominal sensillum

(Belenkaya et al., 1998)

adult cuticle

(Belenkaya et al., 1998)

adult thorax & macrochaeta

(Soldatov et al., 1999, Belenkaya et al., 1998)

leg & external sensory organ

(Soldatov et al., 1999)

mesothoracic leg sensillum

(Belenkaya et al., 1998)

metathoracic leg sensillum

(Belenkaya et al., 1998)

prothoracic leg sensillum

(Belenkaya et al., 1998)

wing

(Soldatov et al., 1999, Belenkaya et al., 1998)

wing sensillum

(Belenkaya et al., 1998)

Detailed Description

Statement

Reference

Body colour: mutant flies have reduced pigmentation in the body and wings and in the thoracic, leg and abdominal bristles.

(Soldatov et al., 1999)

Body colour: pigmentation of all adult cuticle structures is tan.

(Belenkaya et al., 1998)

Body colour: tan. Larval mouth part colour: reduced pigmentation. Larval denticle belt colour: reduced pigmentation.

(Geyer et al., 1990)

Body colour: tan.

(Geyer et al., 1988)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

y^76d28 has abnormal body color phenotype, enhanceable by Taf9¹

(Soldatov et al., 1999)

y^76d28 has abnormal body color phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

y^76d28 has leg & external sensory organ phenotype, enhanceable by Taf9¹

(Soldatov et al., 1999)

y^76d28 has adult thorax & macrochaeta phenotype, enhanceable by Taf9¹

(Soldatov et al., 1999)

y^76d28 has adult abdomen & macrochaeta phenotype, enhanceable by Taf9¹

(Soldatov et al., 1999)

y^76d28 has adult abdominal sensillum phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y^76d28 has adult thorax & macrochaeta phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y^76d28 has adult cuticle phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y^76d28 has wing sensillum phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y^76d28 has prothoracic leg sensillum phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y^76d28 has mesothoracic leg sensillum phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

y^76d28 has metathoracic leg sensillum phenotype, enhanceable by ph-p^P1

(Belenkaya et al., 1998)

Suppressed by

Statement

Reference

y^76d28 has phenotype, suppressible by su(sable)⁹⁴

(Geyer et al., 1991)

y^76d28 has phenotype, suppressible by su(sable)⁹⁵

(Geyer et al., 1991)

Additional Comments

Genetic Interactions

Statement

Reference

Pigmentation of the thoracic, leg and abdominal bristles is further reduced in combination with e(y)1¹.

(Soldatov et al., 1999)

The phenotype is enhanced by ph-p^P1; pigmentation of the body, and of the thoracic, leg, wing and abdominal bristles is further reduced in y^76d28 ph-p^P1 flies.

(Belenkaya et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Geyer.

Comments

Reverts to wild-type.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

y^76d28

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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