FlyBase Allele Report: Dmel\w[IR6]

General Information

Symbol

Dmel\w^IR6

Species

D. melanogaster

Name

Inducer Reactive 6

FlyBase ID

FBal0018264

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

I{}w-IR6

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

IR-hybrid dysgenesis

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Lajoinie et al., 1995)

Mutagen

IR-hybrid dysgenesis

(Bucheton, 1990)

Progenitor genotype

Associated Insertion(s)

I{}w-IR6

Cytology

Description

Insertion of an I-element.

(Bhadra et al., 1997)

I-element insertion.

(Bhadra and Birchler, 1996, Rabinow and Birchler, 1989)

Insertion of a full length I-element into the large first intron at +3176 (FBrf0041384 and FBrf0040782). The transcriptional orientation of the I-element is the same as that of the w locus. The full length I-element insertion is preceeded by 3 repetitions of the first 6 nucleotides of the I-element.

(Lajoinie et al., 1995)

Insertion into non-translated region of the w gene.

(Vaury et al., 1995)

Parallel I-element insertion into intron 1.

(Csink et al., 1994)

I element insertion.

(Birchler and Hiebert, 1989)

5.4kb I-element insertion 5.4kb I insertion map site (kb): +3.2; Origin = insertion of w^a copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Desset et al., 1999, Bhadra et al., 1997)

abnormal eye color | recessive

(Lajoinie et al., 1995)

visible | recessive

Phenotype Manifest In

pigment cell

(Desset et al., 1999, Lajoinie et al., 1995)

Detailed Description

Statement

Reference

Eye colour: orange.

(Desset et al., 1999)

Flies have red-brown eyes.

(Lajoinie et al., 1995)

Eye colour: red-brown, at all temperatures.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

w^IR6 has abnormal eye color | recessive phenotype, suppressible by Low¹

(Bhadra et al., 1997)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^IR6 has phenotype, enhanceable by Mow^gamma

(Bhadra and Birchler, 1996)

w^IR6 has phenotype, enhanceable by Wow^γb

(Birchler et al., 1994)

w^IR6 has phenotype, enhanceable by Wow^γe

(Birchler et al., 1994)

w^IR6 has phenotype, enhanceable by Wow^ems1

(Birchler et al., 1994)

w^IR6 has phenotype, enhanceable by Wow^hd1

(Birchler et al., 1994)

w^IR6 has phenotype, enhanceable by Rm62^E

(Csink et al., 1994)

w^IR6 has phenotype, enhanceable by Rm62^F

(Csink et al., 1994)

w^IR6 has phenotype, enhanceable by Rm62^H

(Csink et al., 1994)

w^IR6 has phenotype, enhanceable by Rm62^K

(Csink et al., 1994)

w^IR6 has phenotype, enhanceable by Rm62^D

(Csink et al., 1994)

w^IR6 has phenotype, enhanceable by Rm62^Dem

(Csink et al., 1994)

NOT Enhanced by

Statement

Reference

w^IR6 has phenotype, non-enhanceable by Ufo¹

(Bhadra et al., 1997)

w^IR6 has phenotype, non-enhanceable by In(3)Msu¹

(Csink et al., 1994)

w^IR6 has phenotype, non-enhanceable by In(3)Msu²

(Csink et al., 1994)

w^IR6 has phenotype, non-enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

w^IR6 has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa³

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa⁴

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa⁵

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa⁷

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa⁸

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-enhanceable by Doa⁹

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

w^IR6 has pigment cell phenotype, suppressible by Low¹

(Bhadra et al., 1997)

NOT suppressed by

Statement

Reference

w^IR6 has phenotype, non-suppressible by Ufo¹

(Bhadra et al., 1997)

w^IR6 has phenotype, non-suppressible by In(3)Msu¹

(Csink et al., 1994)

w^IR6 has phenotype, non-suppressible by In(3)Msu²

(Csink et al., 1994)

w^IR6 has phenotype, non-suppressible by Doa⁹

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa³

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa⁴

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa⁵

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa⁷

(Rabinow and Birchler, 1989)

w^IR6 has phenotype, non-suppressible by Doa⁸

(Rabinow and Birchler, 1989)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Pelisson.

Comments

The I-element insertion in w^IR1 interferes with the normal processing of w gene transcripts.

(Lajoinie et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

w^IR6

(Conte et al., 2002)

Name Synonyms

Inducer Reactive 6

Secondary FlyBase IDs

References (19)

Report Sections

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