FB2024_03 , released June 25, 2024
Aberration: Dmel\In(3)Msu2
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General Information
Symbol
In(3)Msu2
Species
D. melanogaster
Name
FlyBase ID
FBab0023860
Feature type
Also Known As
DoaMsu2, Msu2
Computed Breakpoints include

h47-h58;98F

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints

h47-h58;98F

Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

There are multiple breaks on the third chromosome, but both In(3)Msu1 and In(3)Msu2 have inversions with breaks near the centric heterochromatin and 98F.

All limits from polytene analysis (FBrf0068460)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Homozygotes are sterile. Semi-lethal. Heteroallelic In(3)Msu1/In(3)Msu2 flies are recovered at 4% of the expected value. Male heteroallelic escapers are recovered at about 50% the rate of female escapers. Modifies the phenotype of wa such that a mottled stripe of brilliant red at the posterior of the eye. In(3)Msu1/In(3)Msu2 escapers act as strong suppressors of wa and also recessive enhancers of synaptic-dependent gene expression at w. Testes of wa, In(3)Msu1 also show increased pigmentation with respect to wa. In(3)Msu1/In(3)Msu2 enhances the zeste effect of z1, wzl, producing white eyes, but has no effect on z1, wzm.

    Homozygous lethal. Rare homozygous adult escapers display a rough eye phenotype. Adult retina and ocelli are devoid of photoreceptors. Pigment cell lattice has random distribution of pigment cells and interruptions to the pattern.

    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Attempts to generate revertants with γ ray and ethyl methanesulfonate were unsuccessful.

    Synonyms and Secondary IDs (4)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
    • FBal0038915
    • FBal0038755
    References (7)