FlyBase Allele Report: Dmel\Rm62[F]

General Information

Symbol

Dmel\Rm62^F

Species

D. melanogaster

Name

FlyBase ID

FBal0038892

Feature type

allele

Associated gene

Dmel\Rm62

Associated Insertion(s)

Carried in Construct

Also Known As

Lip^F

Key Links

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Csink et al., 1994)

Progenitor genotype

Cytology

Description

No visible cytological rearrangements.

(Csink et al., 1994)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate | larval stage (with Rm62^CB02119)

(Buszczak and Spradling, 2006)

lethal (with Rm62⁰¹⁰⁸⁶)

(Buszczak and Spradling, 2006)

lethal (with Rm62^CB02119)

(Buszczak and Spradling, 2006)

lethal | recessive

(Csink et al., 1994)

Phenotype Manifest In

Detailed Description

Statement

Reference

Rm62^CB02119/Rm62^F mutants cells show defective RNA export as labelled RNA remains associated with the chromosomes in a tight banded pattern instead of diffusing throughout the nucleoplasm and cytoplasm, as occurs in control cells. Furthermore, the export factors sbr and Aly are redistributed within the nuclei of the mutant cells. Rm62^CB02119/Rm62^F cells also show defects in gene deactivation as evidenced by Br-UTP incorporation experiments.

Some Rm62^CB02119/Rm62^F transheterozygous mutants remain as third instar larvae for up to 5 days, whereas control animals enter prepupal development after 12 days.

(Buszczak and Spradling, 2006)

Heteroallelic combination with Rm62^Dem can be recovered.

(Csink et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Rm62^F is an enhancer of phenotype of w^aM

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^IR6

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^aR84h

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^IR4

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^a

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^ric

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^IR1

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^bl

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^co

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^IR3

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^IR2

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^a59k1

(Csink et al., 1994)

Rm62^F is an enhancer of phenotype of w^IR5

(Csink et al., 1994)

NOT Enhancer of

Statement

Reference

Rm62^F is a non-enhancer of phenotype of w^c

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^col

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^mo

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^h

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^a3

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^ec3

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^zl

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^sp4

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^sp81d

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^bf

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^Adh.PB

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^sp1

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^Bwx

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^sp55

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^sp2

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^e

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^apl

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^bf2

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^a2

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^is

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^cf

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^t

(Csink et al., 1994)

Rm62^F is a non-enhancer of phenotype of w^a4

(Csink et al., 1994)

Suppressor of

Statement

Reference

Rm62^F is a suppressor of phenotype of wⁱ

(Csink et al., 1994)

NOT Suppressor of

Statement

Reference

Rm62^F is a non-suppressor of phenotype of w^c

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^sp4

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^a3

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^a4

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^apl

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^bf

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^bf2

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^cf

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^e

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^h

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^is

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^sp1

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^col

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^sp55

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^t

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^zl

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^mo

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^ec3

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^sp81d

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^sp2

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^a2

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^Adh.PB

(Csink et al., 1994)

Rm62^F is a non-suppressor of phenotype of w^Bwx

(Csink et al., 1994)

Additional Comments

Genetic Interactions

Statement

Reference

Rm62^F/Rm62^Dem escapers enhance the eye colour of w^bl and w^a to almost bleach white.

(Csink et al., 1994)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Rm62^CB02119

(Buszczak and Spradling, 2006)

Rm62⁰¹⁰⁸⁶

(Buszczak and Spradling, 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Isolated as a second site modifier of the w^bl mutation causing an enhancement of the eye colour phenotype.

(Csink et al., 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

LIP-F

(Boeke et al., 2011)

Lip^F

(Buszczak and Spradling, 2006, Csink et al., 1994)

Rm62^F

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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