FlyBase Allele Report: Dmel\w[sp4]

General Information

Symbol

Dmel\w^sp4

Species

D. melanogaster

Name

spotted 4

FlyBase ID

FBal0018305

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

spontaneous

X ray

(Davison et al., 1985, Zachar and Bingham, 1982)

Progenitor genotype

Cytology

Description

Deletion of sequences in the 5' regulatory region.

(Bhadra et al., 1997)

Deficiency in 5' regulatory region.

(Bhadra and Birchler, 1996, Csink et al., 1994)

Deficiency in 5' cis-regulatory region.

(Rabinow et al., 1991, Birchler and Hiebert, 1989, Chapman and Bingham, 1985)

Deficiency in 5' cis regulatory region.

(Rabinow and Birchler, 1989)

Deletion of 1kb between nucleotide positions -2200 and -1029.

(Davison et al., 1985)

Deletion of 1.1kb from map position +4.9 to +6.0 relative to the transcription start site of w.

(Collins et al., 1983)

Deletion of 1.2kb between coordinates +5 and +6.4, using coordinate system of FBrf0038648 where coordinate 0 is the copia insert of w^a.

(Zachar and Bingham, 1982)

deletion in regulatory region map site (kb): +4.78 to +5.85; Origin = insertion of w^a copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

X:2,797,571..2,798,371 [-]

Comment:

Deletion endpoints from FBrf0041384 and GB:X02974.

(O'Hare et al., 1984)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Bhadra et al., 1997)

visible | recessive

Phenotype Manifest In

pigment cell

(Bhadra et al., 1997)

Detailed Description

Statement

Reference

Fails to respond to E(w^a).

(Birchler and Hiebert, 1989)

Phenotype is not affected by Doa mutations.

(Rabinow and Birchler, 1989)

Eye colour: yellowish to brown; fine-grained mottling; male darker than female.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

w^sp4 has abnormal eye color phenotype, enhanceable by z^v77h

(Georgiev, 1994)

w^sp4 has abnormal eye color phenotype, enhanceable by z¹

(Georgiev, 1994)

w^sp4, z^v77h has abnormal eye color phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp4, z¹ has abnormal eye color phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp4, z^v77h has abnormal eye color phenotype, enhanceable by e(y)2¹

(Georgiev, 1994)

w^sp4, z^v77h has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4, z¹ has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4, z^op6 has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4, z^op6R1 has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

NOT Enhanced by

Statement

Reference

w^sp4, z¹ has abnormal eye color phenotype, non-enhanceable by e(y)2¹

(Georgiev, 1994)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^sp4 has phenotype, enhanceable by Wow^γe

(Birchler et al., 1994)

w^sp4 has phenotype, enhanceable by Wow^ems1

(Birchler et al., 1994)

w^sp4 has phenotype, enhanceable by Wow^hd1

(Birchler et al., 1994)

w^sp4 has phenotype, enhanceable by Wow^γb

(Birchler et al., 1994)

w^sp4 has phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp4 has phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4 has pigment cell phenotype, enhanceable by z^v77h

(Georgiev, 1994)

w^sp4 has pigment cell phenotype, enhanceable by z¹

(Georgiev, 1994)

w^sp4, z^v77h has pigment cell phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp4, z¹ has pigment cell phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp4, z^v77h has pigment cell phenotype, enhanceable by e(y)2¹

(Georgiev, 1994)

w^sp4, z^v77h has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4, z¹ has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4, z^op6 has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp4, z^op6R1 has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

NOT Enhanced by

Statement

Reference

w^sp4 has phenotype, non-enhanceable by Low¹

(Bhadra et al., 1997)

w^sp4 has phenotype, non-enhanceable by Ufo¹

(Bhadra et al., 1997)

w^sp4 has phenotype, non-enhanceable by In(3)Msu¹

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by In(3)Msu²

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by Rm62^D

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by Rm62^Dem

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by Rm62^E

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by Rm62^F

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by Rm62^H

(Csink et al., 1994)

w^sp4 has phenotype, non-enhanceable by Rm62^K

(Csink et al., 1994)

w^sp4, z¹ has pigment cell phenotype, non-enhanceable by e(y)2¹

(Georgiev, 1994)

Suppressed by

Statement

Reference

w^sp4 has phenotype, suppressible by Mow^gamma

(Bhadra and Birchler, 1996)

w^sp4 has phenotype, suppressible by east¹

(Chapman and Bingham, 1985)

NOT suppressed by

Statement

Reference

w^sp4 has phenotype, non-suppressible by Low¹

(Bhadra et al., 1997)

w^sp4 has phenotype, non-suppressible by Ufo¹

(Bhadra et al., 1997)

w^sp4 has phenotype, non-suppressible by In(3)Msu¹

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by In(3)Msu²

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Rm62^D

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Rm62^Dem

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Rm62^E

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Rm62^F

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Rm62^H

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Rm62^K

(Csink et al., 1994)

w^sp4 has phenotype, non-suppressible by Pcf11^γc

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^γd

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^EMS3

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^EMS4

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^EMS5

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^hd1

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^γsc

(Rabinow et al., 1991)

w^sp4 has phenotype, non-suppressible by Pcf11^γb

(Rabinow et al., 1991)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

LeFever.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

sp-w⁴

w^sp4

Name Synonyms

spotted 4

spotted-4

(Rabinow and Birchler, 1989)

Secondary FlyBase IDs

References (17)

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