FlyBase Allele Report: Dmel\Pcf11[hd1]

General Information

Symbol

Dmel\Pcf11^hd1

Species

D. melanogaster

Name

FlyBase ID

FBal0029866

Feature type

allele

Associated gene

Dmel\Pcf11

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

PM hybrid dysgenesis

Nature of the Allele

Allele class

loss of function allele

(Rabinow et al., 1991)

Mutagen

PM hybrid dysgenesis

(Rabinow et al., 1991)

Progenitor genotype

Cytology

Description

Point mutation in the consensus splicing donor site of intron 4, resulting in the production of a truncated transcript.

(Xie and Birchler, 2012)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2R:14,868,624..14,868,624 [-]

Nucleotide change:

A14868624G

Comment:

GTAAGT to GTAGGT substitution in the splice donor site of intron 4.

(Xie and Birchler, 2012)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of larval stage | recessive

(Rabinow et al., 1991)

some die during larval stage | recessive

(Rabinow et al., 1991)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Pcf11^hd1 is a suppressor of phenotype of w^a2

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^IRI

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^col

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^a59k1

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^aM

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^aR84h

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^Bwx

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^a

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^a3

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^a4

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^bf

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^cf

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^h

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^sat

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^bl

(Rabinow et al., 1991)

Pcf11^hd1 is a suppressor of phenotype of w^IR2

(Rabinow et al., 1991)

NOT Suppressor of

Statement

Reference

Pcf11^hd1 is a non-suppressor of phenotype of w^sp81d

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of w^sp2

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of w^sp4

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of w^c

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of w^apl

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of w^e

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of wⁱ

(Rabinow et al., 1991)

Pcf11^hd1 is a non-suppressor of phenotype of w^sp1

(Rabinow et al., 1991)

Additional Comments

Genetic Interactions

Statement

Reference

Darkens eye colour: elevation of pigment levels of w^a, and darker Malpighian tubules and testes.

(Rabinow et al., 1991)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Pcf11^k08015

(Xie and Birchler, 2012)

Comments

Inr-a^k08015 fails to complement the recessive lethality of Inr-a^hd1.

(Xie and Birchler, 2012)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Stable mutation that cannot be reverted by P element transposase with P{Δ2-3}.

(Rabinow et al., 1991)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Inr-a^hd1

(Xie and Birchler, 2012)

Pcf11^hd1

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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