FlyBase Allele Report: Dmel\w[IR2]

General Information

Symbol

Dmel\w^IR2

Species

D. melanogaster

Name

Inducer Reactive 2

FlyBase ID

FBal0018260

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

I{}w^IR2

Carried in Construct

Key Links

Allele class

Mutagen

IR-hybrid dysgenesis

Nature of the Allele

Allele class

Mutagen

IR-hybrid dysgenesis

(O'Hare et al., 1991, Rabinow et al., 1991)

Progenitor genotype

w¹

(O'Hare et al., 1991)

Associated Insertion(s)

I{}w^IR2

Cytology

Description

I-element insertion at nucleotides 779--790 of the w¹ Doc element.

(O'Hare et al., 1991)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Benevolenskaya et al., 2000, Bhadra et al., 1997)

abnormal eye color | recessive

visible | recessive

Phenotype Manifest In

pigment cell

(Benevolenskaya et al., 2000, Benevolenskaya et al., 1998)

Detailed Description

Statement

Reference

Pigmented.

(O'Hare et al., 1991)

Suppression by Inr-a is variable.

(Rabinow et al., 1991)

Eye colour: brown at all temperatures.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

w^IR2 has abnormal eye color phenotype, enhanceable by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

Suppressed by

Statement

Reference

w^IR2 has abnormal eye color | recessive phenotype, suppressible by Low¹

(Bhadra et al., 1997)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^IR2 has pigment cell phenotype, enhanceable by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^IR2 has phenotype, enhanceable by Mow^gamma

(Bhadra and Birchler, 1996)

w^IR2 has phenotype, enhanceable by Wow^γb

(Birchler et al., 1994)

w^IR2 has phenotype, enhanceable by Wow^γe

(Birchler et al., 1994)

w^IR2 has phenotype, enhanceable by Wow^ems1

(Birchler et al., 1994)

w^IR2 has phenotype, enhanceable by Wow^hd1

(Birchler et al., 1994)

w^IR2 has phenotype, enhanceable by Rm62^D

(Csink et al., 1994)

w^IR2 has phenotype, enhanceable by Rm62^Dem

(Csink et al., 1994)

w^IR2 has phenotype, enhanceable by Rm62^E

(Csink et al., 1994)

w^IR2 has phenotype, enhanceable by Rm62^F

(Csink et al., 1994)

w^IR2 has phenotype, enhanceable by Rm62^H

(Csink et al., 1994)

w^IR2 has phenotype, enhanceable by Rm62^K

(Csink et al., 1994)

NOT Enhanced by

Statement

Reference

w^IR2 has phenotype, non-enhanceable by Ufo¹

(Bhadra et al., 1997)

w^IR2 has phenotype, non-enhanceable by In(3)Msu¹

(Csink et al., 1994)

w^IR2 has phenotype, non-enhanceable by In(3)Msu²

(Csink et al., 1994)

w^IR2 has phenotype, non-enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

w^IR2 has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa³

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa⁴

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa⁵

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa⁷

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa⁸

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-enhanceable by Doa⁹

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

w^IR2 has pigment cell phenotype, suppressible by Low¹

(Bhadra et al., 1997)

w^IR2 has phenotype, suppressible by Pcf11^γb

(Rabinow et al., 1991)

w^IR2 has phenotype, suppressible by Pcf11^γc

(Rabinow et al., 1991)

w^IR2 has phenotype, suppressible by Pcf11^γd

(Rabinow et al., 1991)

w^IR2 has phenotype, suppressible by Pcf11^EMS3

(Rabinow et al., 1991)

w^IR2 has phenotype, suppressible by Pcf11^EMS4

(Rabinow et al., 1991)

w^IR2 has phenotype, suppressible by Pcf11^EMS5

(Rabinow et al., 1991)

w^IR2 has phenotype, suppressible by Pcf11^hd1

(Rabinow et al., 1991)

NOT suppressed by

Statement

Reference

w^IR2 has phenotype, non-suppressible by Ufo¹

(Bhadra et al., 1997)

w^IR2 has phenotype, non-suppressible by In(3)Msu¹

(Csink et al., 1994)

w^IR2 has phenotype, non-suppressible by In(3)Msu²

(Csink et al., 1994)

w^IR2 has phenotype, non-suppressible by Doa⁹

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa³

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa⁴

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa⁵

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa⁷

(Rabinow and Birchler, 1989)

w^IR2 has phenotype, non-suppressible by Doa⁸

(Rabinow and Birchler, 1989)

Other

Statement

Reference

sgl⁰⁵⁰⁰⁷, w^IR2 has pigment cell phenotype

(Benevolenskaya et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Pelisson.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

w^IR2

Name Synonyms

Inducer Reactive 2

Secondary FlyBase IDs

References (16)

Report Sections

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