FlyBase Allele Report: Dmel\w[a4]

General Information

Symbol

Dmel\w^a4

Species

D. melanogaster

Name

apricot-4

FlyBase ID

FBal0018198

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

3S18{}w^a4

Carried in Construct

Key Links

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Zachar and Bingham, 1982)

Progenitor genotype

Associated Insertion(s)

3S18{}w^a4

Cytology

Description

Insertion of a 3S18 element into the second intron.

(Bhadra et al., 1997)

3S18 insertion into intron 2.

(Bhadra and Birchler, 1996, Csink et al., 1994, Rabinow and Birchler, 1989)

Insertion of a 3S18 element.

(Soriano et al., 1995)

7.2kb 3S18 insert near the centre of the w locus.

(Lim and Simmons, 1994)

BEL insertion in intron 2.

(Rabinow et al., 1991)

BEL insertion into an intron.

(Peng and Mount, 1990)

BEL insertion into intron 2.

(Birchler and Hiebert, 1989)

Insertion of 3S18 element.

(Georgiev and Gerasimova, 1989)

3S18 insertion within the w locus.

(Zachar and Bingham, 1982)

7.3kb BEL insertion in intron 2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Bhadra et al., 1997, Peng and Mount, 1995, Birchler et al., 1989, Zachar and Bingham, 1982)

visible | recessive

(Zachar and Bingham, 1982)

Phenotype Manifest In

Malpighian tubule

pigment cell

(Peng and Mount, 1995, Birchler et al., 1989, Zachar and Bingham, 1982)

Detailed Description

Statement

Reference

Eye colour: orange-brown.

(Zachar and Bingham, 1982)

Eye colour: yellow-orange in male; lighter, yellower, in female; both sexes paler than w^a. Malpighian tubule colour: colourless.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

w^a4 has abnormal eye color phenotype, enhanceable by mw¹

(Birchler et al., 1989)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^a4 has phenotype, enhanceable by Ufo¹

(Bhadra et al., 1997)

w^a4 has phenotype, enhanceable by B52^ED

(Peng and Mount, 1995)

w^a4 has phenotype, enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

w^a4 has pigment cell phenotype, enhanceable by mw¹

(Birchler et al., 1989)

w^a4 has phenotype, enhanceable by mw^3P

(Birchler et al., 1989)

NOT Enhanced by

Statement

Reference

w^a4 has phenotype, non-enhanceable by Low¹

(Bhadra et al., 1997)

w^a4 has phenotype, non-enhanceable by Mow^gamma

(Bhadra and Birchler, 1996)

w^a4 has phenotype, non-enhanceable by Rm62^Dem

(Csink et al., 1994)

w^a4 has phenotype, non-enhanceable by Rm62^E

(Csink et al., 1994)

w^a4 has phenotype, non-enhanceable by Rm62^F

(Csink et al., 1994)

w^a4 has phenotype, non-enhanceable by Rm62^H

(Csink et al., 1994)

w^a4 has phenotype, non-enhanceable by Rm62^K

(Csink et al., 1994)

w^a4 has phenotype, non-enhanceable by Rm62^D

(Csink et al., 1994)

w^a4 has phenotype, non-enhanceable by mw^2a

(Birchler et al., 1989)

w^a4 has phenotype, non-enhanceable by mod(mdg4)^ul

(Georgiev and Gerasimova, 1989)

w^a4 has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa³

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa⁴

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa⁵

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa⁷

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa⁸

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-enhanceable by Doa⁹

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

w^a4 has phenotype, suppressible by Wow^γb

(Birchler et al., 1994)

w^a4 has phenotype, suppressible by Wow^γe

(Birchler et al., 1994)

w^a4 has phenotype, suppressible by Wow^ems1

(Birchler et al., 1994)

w^a4 has phenotype, suppressible by Wow^hd1

(Birchler et al., 1994)

w^a4 has phenotype, suppressible by In(3)Msu¹

(Csink et al., 1994)

w^a4 has phenotype, suppressible by In(3)Msu²

(Csink et al., 1994)

w^a4 has phenotype, suppressible by Su(w^a4)^M1

(Khatpova and Gerasimova, 1992)

w^a4 has phenotype, suppressible by Pcf11^γb

(Rabinow et al., 1991)

w^a4 has phenotype, suppressible by Pcf11^γc

(Rabinow et al., 1991)

w^a4 has phenotype, suppressible by Pcf11^γd

(Rabinow et al., 1991)

w^a4 has phenotype, suppressible by Pcf11^EMS3

(Rabinow et al., 1991)

w^a4 has phenotype, suppressible by Pcf11^EMS4

(Rabinow et al., 1991)

w^a4 has phenotype, suppressible by Pcf11^EMS5

(Rabinow et al., 1991)

w^a4 has phenotype, suppressible by Pcf11^hd1

(Rabinow et al., 1991)

NOT suppressed by

Statement

Reference

w^a4 has phenotype, non-suppressible by Low¹

(Bhadra et al., 1997)

w^a4 has phenotype, non-suppressible by Mow^gamma

(Bhadra and Birchler, 1996)

w^a4 has phenotype, non-suppressible by Rm62^D

(Csink et al., 1994)

w^a4 has phenotype, non-suppressible by Rm62^Dem

(Csink et al., 1994)

w^a4 has phenotype, non-suppressible by Rm62^E

(Csink et al., 1994)

w^a4 has phenotype, non-suppressible by Rm62^F

(Csink et al., 1994)

w^a4 has phenotype, non-suppressible by Rm62^H

(Csink et al., 1994)

w^a4 has phenotype, non-suppressible by Rm62^K

(Csink et al., 1994)

w^a4 has phenotype, non-suppressible by mod(mdg4)^ul

(Georgiev and Gerasimova, 1989)

w^a4 has phenotype, non-suppressible by Doa³

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa⁴

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa⁵

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa⁷

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa⁸

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa⁹

(Rabinow and Birchler, 1989)

w^a4 has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

Other

Statement

Reference

In(3)Msu¹/+, w^a4 has pigment cell phenotype

(Csink et al., 1994)

In(3)Msu²/+, w^a4 has pigment cell phenotype

(Csink et al., 1994)

Additional Comments

Genetic Interactions

Statement

Reference

Shows mosaic suppression by In(3)Msu¹/+ or In(3)Msu²/+: eyes have a mottled stripe of brilliant red at the posterior.

(Csink et al., 1994)

Eye colour: mottled, with mw¹.

(Birchler et al., 1989)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

152

w^a4

Kyoto

100989

C(1)DX, y¹ f¹ / Dp(1;1)w^a, z¹ w^a w^a4

100984

C(1)DX, y¹ f¹ / Dp(1;1)3C3, y² su(w^a)¹ w^a4

Notes on Origin

Discoverer

Nichols-Skoog, 12th March 1935.

Comments

The alkylating agents EMS, MMS, and ENU induce a clear increase in the frequency of somatic revertant sectors in the eye in w^a4 flies.

(Soriano et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

w^a4

wa4

(Soriano et al., 1997)

Name Synonyms

apricot-4

Secondary FlyBase IDs

References (26)

Report Sections

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