FlyBase Allele Report: Dmel\w[h]

General Information

Symbol

Dmel\w^h

Species

D. melanogaster

Name

honey

FlyBase ID

FBal0018246

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

roo{}w^h

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Rabinow and Birchler, 1990)

Mutagen

spontaneous

(O'Hare et al., 1991, Zachar and Bingham, 1982)

Progenitor genotype

w¹

(O'Hare et al., 1991)

Associated Insertion(s)

roo{}w^h

Cytology

Polytene chromosomes normal.

(Larsson et al., 1996)

Description

roo is inserted into the Doc element of w¹.

(O'Hare et al., 1991)

5.7kb roo insertion in Doc element map site (kb): +3.71; Origin = insertion of w^a copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Benevolenskaya et al., 2000, Bhadra et al., 1997, Heinrich et al., 1993, Birchler et al., 1989)

abnormal eye color | recessive

(Frolov et al., 1998, Kaufman, 1969)

visible | recessive

Phenotype Manifest In

Malpighian tubule

pigment cell

(Benevolenskaya et al., 2000, Benevolenskaya et al., 1998, Frolov et al., 1998, Heinrich et al., 1993, Birchler et al., 1989, Zachar and Bingham, 1982, Kaufman, 1969)

Detailed Description

Statement

Reference

Eye colour: unaffected by LTSV\RBZ^hs.w.

(Heinrich et al., 1993)

Eye colour: mottled with mw.

(Rabinow and Birchler, 1990)

Eye colour: light yellow.

(Zachar and Bingham, 1982)

Eye colour: The w^cf2 eye colour is not diluted when w^cf2 is in transheterozygous combination with w^h.

(Kaufman, 1969)

Eye colour: between w^bf and w^a4; slightly darker in male than in female. Malpighian tubule colour: colourless.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

w^h has abnormal eye color phenotype, enhanceable by mw¹

(Birchler et al., 1989)

NOT Enhanced by

Statement

Reference

w^h has abnormal eye color phenotype, non-enhanceable by Rga⁰³⁸³⁴

(Frolov et al., 1998)

Suppressed by

Statement

Reference

w^h has abnormal eye color phenotype, suppressible by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^h has abnormal eye color | recessive phenotype, suppressible by Low¹

(Bhadra et al., 1997)

NOT suppressed by

Statement

Reference

w^h has abnormal eye color phenotype, non-suppressible by Rga⁰³⁸³⁴

(Frolov et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^h has phenotype, enhanceable by mw²

(Rabinow and Birchler, 1990)

w^h has phenotype, enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

w^h has pigment cell phenotype, enhanceable by mw¹

(Birchler et al., 1989)

w^h has phenotype, enhanceable by e(w^e)¹

NOT Enhanced by

Statement

Reference

w^h has phenotype, non-enhanceable by Ufo¹

(Bhadra et al., 1997)

w^h has phenotype, non-enhanceable by Wow^γb

(Birchler et al., 1994)

w^h has phenotype, non-enhanceable by Wow^γe

(Birchler et al., 1994)

w^h has phenotype, non-enhanceable by Wow^ems1

(Birchler et al., 1994)

w^h has phenotype, non-enhanceable by Wow^hd1

(Birchler et al., 1994)

w^h has phenotype, non-enhanceable by Rm62^D

(Csink et al., 1994)

w^h has phenotype, non-enhanceable by Rm62^Dem

(Csink et al., 1994)

w^h has phenotype, non-enhanceable by Rm62^E

(Csink et al., 1994)

w^h has phenotype, non-enhanceable by Rm62^F

(Csink et al., 1994)

w^h has phenotype, non-enhanceable by Rm62^H

(Csink et al., 1994)

w^h has phenotype, non-enhanceable by Rm62^K

(Csink et al., 1994)

w^h has phenotype, non-enhanceable by Doa⁹

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa³

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa⁴

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa⁵

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa⁷

(Rabinow and Birchler, 1989)

w^h has phenotype, non-enhanceable by Doa⁸

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

w^h has pigment cell phenotype, suppressible by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^h has pigment cell phenotype, suppressible by Low¹

(Bhadra et al., 1997)

w^h has phenotype, suppressible by Mow^gamma

(Bhadra and Birchler, 1996)

w^h has pigment cell phenotype, suppressible by In(3)Msu¹/+

(Csink et al., 1994)

w^h has pigment cell phenotype, suppressible by In(3)Msu²/+

(Csink et al., 1994)

w^h has phenotype, suppressible by Pcf11^γb

(Rabinow et al., 1991)

w^h has phenotype, suppressible by Pcf11^γc

(Rabinow et al., 1991)

w^h has phenotype, suppressible by Pcf11^γd

(Rabinow et al., 1991)

w^h has phenotype, suppressible by Pcf11^EMS3

(Rabinow et al., 1991)

w^h has phenotype, suppressible by Pcf11^EMS4

(Rabinow et al., 1991)

w^h has phenotype, suppressible by Pcf11^EMS5

(Rabinow et al., 1991)

w^h has phenotype, suppressible by Pcf11^hd1

(Rabinow et al., 1991)

NOT suppressed by

Statement

Reference

w^h has phenotype, non-suppressible by Ufo¹

(Bhadra et al., 1997)

w^h has phenotype, non-suppressible by Wow^γb

(Birchler et al., 1994)

w^h has phenotype, non-suppressible by Wow^γe

(Birchler et al., 1994)

w^h has phenotype, non-suppressible by Wow^ems1

(Birchler et al., 1994)

w^h has phenotype, non-suppressible by Wow^hd1

(Birchler et al., 1994)

w^h has phenotype, non-suppressible by Rm62^D

(Csink et al., 1994)

w^h has phenotype, non-suppressible by Rm62^Dem

(Csink et al., 1994)

w^h has phenotype, non-suppressible by Rm62^E

(Csink et al., 1994)

w^h has phenotype, non-suppressible by Rm62^F

(Csink et al., 1994)

w^h has phenotype, non-suppressible by Rm62^H

(Csink et al., 1994)

w^h has phenotype, non-suppressible by Rm62^K

(Csink et al., 1994)

w^h has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa³

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa⁴

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa⁵

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa⁷

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa⁸

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by Doa⁹

(Rabinow and Birchler, 1989)

w^h has phenotype, non-suppressible by su(Hw)²

(Lindsley and Grell, 1968)

Other

Statement

Reference

sgl⁰⁵⁰⁰⁷, w^h has pigment cell phenotype

(Benevolenskaya et al., 1998)

In(3)Msu²/In(3)Msu¹, w^h has pigment cell phenotype

(Csink et al., 1994)

Additional Comments

Genetic Interactions

Statement

Reference

Eye colour: bleach white, with In(3)Msu¹/In(3)Msu².

(Csink et al., 1994)

Suppression by Inr-a is variable.

(Rabinow et al., 1991)

Eye colour: mottled with mw.

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (2)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (2)

Bloomington

162

w^h

Kyoto

101181

sc¹ z¹ w^h

Notes on Origin

Discoverer

Dunn, 27th Oct. 1934.

Comments

The distribution of ry protein in the tissues of the adult fly is altered in this mutant.

(Reaume et al., 1991)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

w^a3

w^h

w^honey

(Heinrich et al., 1993)

(Soriano et al., 1997)

Name Synonyms

honey

Secondary FlyBase IDs

References (32)

Report Sections

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