FlyBase Allele Report: Dmel\w[bl]

General Information

Symbol

Dmel\w^bl

Species

D. melanogaster

Name

blood

FlyBase ID

FBal0018218

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

blood{}w^bl

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Bhadra and Birchler, 1996, Roseman et al., 1995)

Mutagen

spontaneous

Progenitor genotype

Associated Insertion(s)

blood{}w^bl

Cytology

Description

Insertion of a blood element into the 2nd intron.

(Bhadra et al., 1997)

blood insertion into intron 2.

(Bhadra and Birchler, 1996, Roseman et al., 1995)

copia insertion into intron 2.

(Csink et al., 1994)

Insert stated as cause: undefined Insertion of a retrotransposon in the second intron, in antiparallel orientation.

(Sabl and Birchler, 1993)

Antiparallel insertion of a retrotransposon into the second intron.

(Birchler, 1992)

Antiparallel retroposon insertion in intron 2.

(Rabinow et al., 1991)

Retrotransposon insertion in intron 2.

(Birchler and Hiebert, 1989)

Insert stated as cause: undefined Retrotransposon insertion into intron 2.

(Rabinow and Birchler, 1989)

6 kb blood insertion map site (kb): -0.01; Origin = insertion of w^a copia; '-' values to left (telomere) end; '+' values to right (centromere) end.

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

X04671

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Bhadra et al., 1997, Peng and Mount, 1995)

abnormal eye color | heat sensitive

abnormal eye color | recessive

(Frolov et al., 1998)

visible | recessive | heat sensitive

Phenotype Manifest In

Malpighian tubule

pigment cell

(Benevolenskaya et al., 1998, Frolov et al., 1998, Peng and Mount, 1995)

testis pigment cell

Detailed Description

Statement

Reference

Homozygous males are darker than homozygous females. Triple X metafemale individuals homozygous for w^bl have pigment levels near the normal intensity of w^bl homozygous XX females.

(Birchler, 1992)

Temperature sensitivity greatest 40-48 hr after pupation.

(Ephrussi and Herold, 1945)

Eye colour: yellowish-ruby, later se-like; female lighter than male; at 19^oC as dark as pn¹; at 30^oC, as light as w^bf or wⁱ. Testis colour: colourless. Malpighian tubule colour: pale yellow at 25^oC.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

w^bl has abnormal eye color | recessive phenotype, enhanceable by Low¹

(Bhadra et al., 1997)

Suppressed by

Statement

Reference

w^bl has abnormal eye color | recessive phenotype, suppressible by Rga[+]/Rga⁰³⁸³⁴

(Frolov et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^bl has pigment cell phenotype, enhanceable by Low¹

(Bhadra et al., 1997)

w^bl has pigment cell phenotype, enhanceable by Rm62^j14E8

(Csink, 1997.12.9)

w^bl has pigment cell phenotype, enhanceable by Rm62^j3D2

(Csink, 1997.12.9)

w^bl has pigment cell phenotype, enhanceable by Rm62^j3D5

(Csink, 1997.12.9)

w^bl has phenotype, enhanceable by B52^ED

(Peng and Mount, 1995)

w^bl has phenotype, enhanceable by Wow^γb

(Birchler et al., 1994)

w^bl has phenotype, enhanceable by Wow^γe

(Birchler et al., 1994)

w^bl has phenotype, enhanceable by Wow^ems1

(Birchler et al., 1994)

w^bl has phenotype, enhanceable by Wow^hd1

(Birchler et al., 1994)

w^bl has phenotype, enhanceable by Rm62^D

(Csink et al., 1994)

w^bl has phenotype, enhanceable by Rm62^Dem

(Csink et al., 1994)

w^bl has phenotype, enhanceable by Rm62^E

(Csink et al., 1994)

w^bl has phenotype, enhanceable by Rm62^F

(Csink et al., 1994)

w^bl has phenotype, enhanceable by Rm62^H

(Csink et al., 1994)

w^bl has phenotype, enhanceable by Rm62^K

(Csink et al., 1994)

w^bl has phenotype, enhanceable by Ts(YSt;2Lt)A24+Ts(YLt;2Rt)L23

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)A24+Ts(YLt;2Lt)B107

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Lt)R14+Ts(YSt;2Rt)L110

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)H149+Ts(YLt;2Lt)L107

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)B202

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)A120

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)R104

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YSt;2Lt)L11+Ts(YLt;2Rt)P59

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(Y;3Rt)J1+Ts(YSt;3Lt)L132

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;3Lt)B116+Ts(YLt;3Rt)G48

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Lt)D6+Ts(YLt;2Rt)H116

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)L52+Ts(YLt;2Lt)R15

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Dp(2;Y)B231

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YLt;2Rt)G10+Ts(YLt;2Lt)R155

(Sabl and Birchler, 1993)

w^bl has phenotype, enhanceable by Ts(YSt;2Lt)L23+Ts(YSt;2Rt)R155

(Sabl and Birchler, 1993)

NOT Enhanced by

Statement

Reference

w^bl has phenotype, non-enhanceable by In(3)Msu¹

(Csink et al., 1994)

w^bl has phenotype, non-enhanceable by In(3)Msu²

(Csink et al., 1994)

w^bl has phenotype, non-enhanceable by Ts(YLt;2Lt)G120

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;3Lt)A78+Ts(YSt;3Rt)R36

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;2Rt)G146+Ts(2Lt;4Lt)J96+Ts(YSt;4Rt)J96

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;2Lt)H52+Ts(YLt;2Rt)J96

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;2Lt)B110+Ts(YSt;2Rt)R15

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;2Rt)B110+Ts(YLt;2Lt)L138

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;2Rt)B110+Ts(YSt;2Lt)D20

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Dp(2;Y)J64

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;2Rt)L107+Ts(YSt;2Lt)P59

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;3Lt)B141

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;3Lt)A31+Ts(YLt;3Rt)G122

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;2Rt)H52+Ts(YSt;2Lt)L52

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;2Lt)P59+Ts(YLt;2Rt)R104

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;2Rt)L11

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;3Lt)G122+Ts(YSt;3Rt)R86

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(Y;3Lt)J1+Ts(YSt;3Rt)J162

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;3Rt)A78+Ts(YLt;3Lt)D226

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;3Lt)G48+Ts(YSt;3Rt)H172

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;3Rt)B93+Ts(YLt;3Lt)D100

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;3Rt)B93+Ts(YLt;3Lt)G73

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YSt;3Rt)G73+Ts(YSt;3Lt)R128

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by Ts(YLt;3Rt)R128

(Sabl and Birchler, 1993)

w^bl has phenotype, non-enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

w^bl has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa³

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa⁴

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa⁵

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa⁷

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa⁸

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-enhanceable by Doa⁹

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

w^bl has pigment cell phenotype, suppressible by RpLP0⁰¹⁵⁴⁴

(Frolov and Birchler, 1998)

w^bl has pigment cell phenotype, suppressible by Rga[+]/Rga⁰³⁸³⁴

(Frolov et al., 1998)

w^bl has phenotype, suppressible by Ufo¹

(Bhadra et al., 1997)

w^bl has phenotype, suppressible by Mow^gamma

(Bhadra and Birchler, 1996)

w^bl has phenotype, suppressible by Ts(YSt;2Lt)D20+Ts(YSt;2Rt)L138

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YLt;2Rt)D20+Ts(YSt;2Lt)G10

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;2Rt)B107+Ts(YLt;2Lt)L110

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;2Lt)H149+Ts(YSt;2Rt)R14

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Rt)B141+Ts(YSt;3Lt)G122

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Rt)B141+Ts(YLt;3Lt)R86

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Rt)B141+Ts(YSt;3Lt)B234

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Rt)A31+Ts(YSt;3Lt)D228

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YLt;3Rt)D228+Ts(YLt;3Lt)L131

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Rt)L131+Ts(YSt;3Lt)R153

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YLt;3Lt)J162+Ts(YLt;3Rt)R153

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Lt)G48+Ts(YSt;3Rt)R36

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YLt;3Lt)H172+Ts(YSt;3Rt)R36

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Rt)D226+Ts(YLt;3Lt)H172

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Ts(YSt;3Lt)B93+Ts(YSt;3Rt)B116

(Sabl and Birchler, 1993)

w^bl has phenotype, suppressible by Pcf11^γb

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^γc

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^γd

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^EMS3

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^EMS4

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^EMS5

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^hd1

(Rabinow et al., 1991)

w^bl has phenotype, suppressible by Pcf11^γsc

(Rabinow et al., 1991)

NOT suppressed by

Statement

Reference

w^bl has phenotype, non-suppressible by In(3)Msu¹

(Csink et al., 1994)

w^bl has phenotype, non-suppressible by In(3)Msu²

(Csink et al., 1994)

w^bl has phenotype, non-suppressible by Ts(YLt;2Lt)G120

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;3Lt)A78+Ts(YSt;3Rt)R36

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;3Lt)A31+Ts(YLt;3Rt)G122

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;2Rt)H52+Ts(YSt;2Lt)L52

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;2Lt)P59+Ts(YLt;2Rt)R104

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;2Rt)L11

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;3Lt)G122+Ts(YSt;3Rt)R86

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(Y;3Lt)J1+Ts(YSt;3Rt)J162

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;3Rt)A78+Ts(YLt;3Lt)D226

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;3Lt)G48+Ts(YSt;3Rt)H172

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;3Rt)B93+Ts(YLt;3Lt)D100

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;3Rt)B93+Ts(YLt;3Lt)G73

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;2Rt)G146+Ts(2Lt;4Lt)J96+Ts(YSt;4Rt)J96

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;3Rt)G73+Ts(YSt;3Lt)R128

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;3Rt)R128

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;2Lt)H52+Ts(YLt;2Rt)J96

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;2Lt)B110+Ts(YSt;2Rt)R15

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;2Rt)B110+Ts(YLt;2Lt)L138

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;2Rt)B110+Ts(YSt;2Lt)D20

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Dp(2;Y)J64

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YSt;2Rt)L107+Ts(YSt;2Lt)P59

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Ts(YLt;3Lt)B141

(Sabl and Birchler, 1993)

w^bl has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa³

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa⁴

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa⁵

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa⁷

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa⁸

(Rabinow and Birchler, 1989)

w^bl has phenotype, non-suppressible by Doa⁹

(Rabinow and Birchler, 1989)

Other

Statement

Reference

sgl⁰⁵⁰⁰⁷, w^bl has pigment cell phenotype

(Benevolenskaya et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (2)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (3)

Bloomington

4449

w^bl

99691

w^bl; Rm62^H/TM6B, Tb⁺

Kyoto

101176

sc¹ w^bl ec¹

Notes on Origin

Discoverer

Hyde, 10th July 1914.

Comments

Located distal to w^e.

(Green, 1959, Judd, 1958)

Dosage compensating allele.

(Birchler, 1992)

Dosage compensation is not affected by su(Hw)^V.

(Roseman et al., 1995)

Located distal to w¹.

(MacKendrick and Pontecorvo, 1952)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

X04671

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

w^bl

Name Synonyms

blood

Secondary FlyBase IDs

References (28)

Report Sections

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