FlyBase Allele Report: Dmel\w[sp2]

General Information

Symbol

Dmel\w^sp2

Species

D. melanogaster

Name

spotted 2

FlyBase ID

FBal0018303

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

spontaneous

Nature of the Allele

Allele class

Mutagen

spontaneous

(Davison et al., 1985, Zachar and Bingham, 1982)

Progenitor genotype

Cytology

Description

Deletion of sequences in the 5' regulatory region.

(Bhadra et al., 1997)

Deficiency in 5' regulatory region.

(Bhadra and Birchler, 1996, Csink et al., 1994)

Deletion in the 5' regulatory region.

(Larsson et al., 1996)

Deficiency in 5' cis-regulatory region.

(Rabinow et al., 1991, Birchler and Hiebert, 1989, Chapman and Bingham, 1985)

Deficiency in 5' cis regulatory region.

(Rabinow and Birchler, 1989)

Deletion extending from nucleotide -1231 to -1115.

(Davison et al., 1985)

Deletion of 200bp between coordinates +5 and +5.9, using coordinate system of FBrf0038648 where coordinate 0 is the copia insert of w^a.

(Zachar and Bingham, 1982)

deletion in regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Bhadra et al., 1997)

abnormal eye color | recessive

(Frolov et al., 1998)

visible | recessive

Phenotype Manifest In

pigment cell

(Benevolenskaya et al., 1998, Frolov et al., 1998)

testis pigment cell

Detailed Description

Statement

Reference

Shows hyper-dosage compensation.

(Qian and Pirrotta, 1995)

Testis colour: pigmentation enhanced.

(Judd, 1987, Davison et al., 1985, Pirrotta et al., 1985)

Eye colour: yellowish to brown; fine-grained mottling; male darker than female. Eye colour: uniform brown, with w¹. Eye colour: uniform brown, with w^e.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

w^sp2 has abnormal eye color phenotype, enhanceable by z¹

(Georgiev, 1994)

w^sp2, z^v77h has abnormal eye color phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp2, z¹ has abnormal eye color phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp2, z^v77h has abnormal eye color phenotype, enhanceable by e(y)2¹

(Georgiev, 1994)

w^sp2, z^v77h has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2, z¹ has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2, z^op6 has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2, z^op6R1 has abnormal eye color phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2 has abnormal eye color phenotype, enhanceable by z^v77h

(Georgiev, 1994)

NOT Enhanced by

Statement

Reference

w^sp2 has abnormal eye color phenotype, non-enhanceable by Rga⁰³⁸³⁴

(Frolov et al., 1998)

w^sp2, z¹ has abnormal eye color phenotype, non-enhanceable by e(y)2¹

(Georgiev, 1994)

NOT suppressed by

Statement

Reference

w^sp2 has abnormal eye color phenotype, non-suppressible by Rga⁰³⁸³⁴

(Frolov et al., 1998)

Phenotype Manifest In

Enhanced by

Statement

Reference

w^sp2 has phenotype, enhanceable by Wow^γb

(Birchler et al., 1994)

w^sp2 has phenotype, enhanceable by Wow^γe

(Birchler et al., 1994)

w^sp2 has phenotype, enhanceable by Wow^ems1

(Birchler et al., 1994)

w^sp2 has phenotype, enhanceable by Wow^hd1

(Birchler et al., 1994)

w^sp2, z^v77h has pigment cell phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp2, z¹ has pigment cell phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp2, z^v77h has pigment cell phenotype, enhanceable by e(y)2¹

(Georgiev, 1994)

w^sp2, z^v77h has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2, z¹ has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2, z^op6 has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2, z^op6R1 has pigment cell phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2 has phenotype, enhanceable by Taf9¹

(Georgiev, 1994)

w^sp2 has phenotype, enhanceable by e(y)3⁴

(Georgiev, 1994)

w^sp2 has pigment cell phenotype, enhanceable by z^v77h

(Georgiev, 1994)

w^sp2 has pigment cell phenotype, enhanceable by z¹

(Georgiev, 1994)

NOT Enhanced by

Statement

Reference

w^sp2 has phenotype, non-enhanceable by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^sp2 has phenotype, non-enhanceable by Low¹

(Bhadra et al., 1997)

w^sp2 has phenotype, non-enhanceable by Ufo¹

(Bhadra et al., 1997)

w^sp2 has phenotype, non-enhanceable by In(3)Msu¹

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by In(3)Msu²

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by Rm62^D

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by Rm62^Dem

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by Rm62^E

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by Rm62^F

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by Rm62^H

(Csink et al., 1994)

w^sp2 has phenotype, non-enhanceable by Rm62^K

(Csink et al., 1994)

w^sp2, z¹ has pigment cell phenotype, non-enhanceable by e(y)2¹

(Georgiev, 1994)

w^sp2 has phenotype, non-enhanceable by E(w^a)¹

(Birchler and Hiebert, 1989)

w^sp2 has phenotype, non-enhanceable by Doa^HD

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa³

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa⁴

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa⁵

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa⁶

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa⁷

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa⁸

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-enhanceable by Doa⁹

(Rabinow and Birchler, 1989)

Suppressed by

Statement

Reference

w^sp2 has phenotype, suppressible by Mow^gamma

(Bhadra and Birchler, 1996)

w^sp2 has phenotype, suppressible by east¹

(Chapman and Bingham, 1985)

NOT suppressed by

Statement

Reference

w^sp2 has phenotype, non-suppressible by Kr-h1⁰⁵²⁰⁸

(Benevolenskaya et al., 2000)

w^sp2 has phenotype, non-suppressible by Low¹

(Bhadra et al., 1997)

w^sp2 has phenotype, non-suppressible by Ufo¹

(Bhadra et al., 1997)

w^sp2 has phenotype, non-suppressible by In(3)Msu¹

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by In(3)Msu²

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Rm62^D

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Rm62^Dem

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Rm62^E

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Rm62^F

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Rm62^H

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Rm62^K

(Csink et al., 1994)

w^sp2 has phenotype, non-suppressible by Pcf11^γc

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^γd

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^EMS3

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^EMS4

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^EMS5

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^hd1

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^γsc

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Pcf11^γb

(Rabinow et al., 1991)

w^sp2 has phenotype, non-suppressible by Doa^HD

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa³

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa⁴

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa⁵

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa⁶

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa⁷

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa⁸

(Rabinow and Birchler, 1989)

w^sp2 has phenotype, non-suppressible by Doa⁹

(Rabinow and Birchler, 1989)

Other

Statement

Reference

sgl⁰⁵⁰⁰⁷, w^sp2 has pigment cell phenotype

(Benevolenskaya et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

101232

C(1)DX, y¹ w¹ f¹ / y¹ z¹ w^sp2 N^spl-1

Notes on Origin

Discoverer

Mohler, 22nd March 1956.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

w^sp-2

(Sorsa et al., 1973)

w^sp2

Name Synonyms

spotted 2

(Rabinow and Birchler, 1989)

spotted-2

(Rabinow and Birchler, 1989)

Secondary FlyBase IDs

References (26)

Report Sections

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