FB2024_03 , released June 25, 2024
Allele: Dmel\DoaE786
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General Information
Symbol
Dmel\DoaE786
Species
D. melanogaster
Name
FlyBase ID
FBal0059089
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

DoaE786/Doa4 XX females show somatic sex transformations. The flies exhibit typical female pigmentation but a male clasper, female vaginal structures and the female genital sex comb.

The ovaries of DoaE786/DoaDem mutant flies appear normal, despite asymmetry in the female genital sex combs.

Doa7/DoaE786 mutants exhibit defects in the mesothoracic tarsi.

In Doa6/DoaE786 mutants where the Doa6 allele is from the mother only females are recovered. The flies have rough eyes, duplicated postalar bristles, missing scutellar bristles and disorganisation of the vaginal bristles. When the DoaE786 allele comes from the mother there are no survivors.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

DoaE786 is a suppressor of phenotype of wa

Additional Comments
Genetic Interactions
Statement
Reference

Transheterozygotes with wa have red eyes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)