fs(2)trunk
secreted - ligand for torso - crucial for establishment of anterior and posterior cell identity of the embryo - Trunk and Torsolike alone are ineffective but acted synergistically to stimulate Torso signaling
Please see the JBrowse view of Dmel\trk for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
0.8 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
226 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\trk using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
trk transcripts are present in nurse cells but not follicle cells during oogenesis and are ubiquitous in early embryos.
JBrowse - Visual display of RNA-Seq signals
View Dmel\trk in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
trk protein is cleaved multiple times in vivo and these proteolytic events are essential for its function.
The maternal terminal system is necessary to activate tll expression in the terminal caps.
Mutations in maternal terminal class gene trk interact with RpII140wimp.
trk plays a role in the specification of the anterior and posterior pole.
Zygotically active locus involved in the terminal developmental program in the embryo in the embryo.
Mature follicles are immunologically stained for asymmetric distribution of ecdysteroid-related antigen. During late oogenesis localisation of the antigen changes dramatically suggesting the antigen plays a role in early embryogenesis and, perhaps, in pattern formation.
Mutations in trk result in a maternal effect phenotype with defects during the early stages of gastrulation and defects in the anteroposterior axis.