FB2024_03 , released April 23, 2024
FB2024_03 , released April 23, 2024
CV Term Report
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General Information
Term receptor ligand activity ID (Ontology) GO:0048018 (Gene Ontology)
Definition The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
Also Known As "signaling molecule" ; "signaling receptor ligand activity"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
Genes (FBgn)  GO_MOLECULAR_FUNCTION      38
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 receptor ligand activity (all annotations which use CV term, excluding "NOT" statements)       9     38
     enables | receptor ligand activity       --      38
Spanning Tree (Parents/Children)
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protein binding
 |__signaling receptor binding_____________
signaling receptor regulator activity      |
 |__signaling receptor activator activity__|
molecular function activator activity      |
 |__signaling receptor activator activity__|
                                           receptor ligand activity  120 rec.
                                            |__chemoattractant activity 2 rec.
                                            |   |__chemoattractant activity involved in axon guidance
                                            |__chemorepellent activity 5 rec.
                                            |__cytokine activity 27 rec.
                                            |   |__chemokine activity 1 rec.
                                            |__death receptor agonist activity
                                            |__growth factor activity 21 rec.
                                            |__hormone activity 49 rec.
                                            |   |__corticotropin-releasing hormone activity
                                            |   |__digestive hormone activity
                                            |   |__diuretic hormone activity 4 rec.
                                            |   |__follicle-stimulating hormone activity
                                            |   |__gonadotropin hormone-releasing hormone activity
                                            |   |__growth hormone activity
                                            |   |__growth hormone-releasing hormone activity
                                            |   |__melanin-concentrating hormone activity
                                            |   |__melanocyte-stimulating hormone activity
                                            |   |__myoinhibitory hormone activity 1 rec.
                                            |   |__myostimulatory hormone activity 2 rec.
                                            |   |__neuropeptide hormone activity(+) 30 rec.
                                            |   |__pituitary adenylate cyclase activating polypeptide activity
                                            |   |__thyrotropin-releasing hormone activity
                                            |__morphogen activity 5 rec.
                                            |__neuropeptide activity 30 rec.
                                            |   |__neuropeptide hormone activity(+) 30 rec.
                                            |__opioid peptide activity
                                            |__pathogen-derived receptor ligand activity
                                            |__pheromone activity
                                                |__competence pheromone activity
                                                |__mating pheromone activity
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Is a signaling receptor binding
signaling receptor activator activity
Part of
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Synonyms
  • "receptor agonist activity" BROAD
    "signaling molecule" EXACT
    "signaling receptor ligand activity" EXACT
    "vitamin D receptor activator activity" NARROW
Secondary IDs
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