FB2024_03 , released June 25, 2024
Allele: Dmel\trkN.UASp.Tag:MYC,mCherry
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General Information
Symbol
Dmel\trkN.UASp.Tag:MYC,mCherry
Species
D. melanogaster
Name
FlyBase ID
FBal0318480
Feature type
allele
Associated gene
Dmel\trk
Associated Insertion(s)
Carried in Construct
P{UASp-Ntrk.Myc.mCh}
Key Links
Transgenic product class
inframe_deletion
(Johnson et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Johnson et al., 2015)
Mutagen
in vitro construct
(Johnson et al., 2015)
Progenitor genotype
Carried in construct
P{UASp-Ntrk.Myc.mCh}
Cytology
Description

UASp regulatory sequences drive expression of trk lacking amino acid residues 143-235 followed by a short linker peptide (SAGSAS), three tandem Tag:MYC epitopes and the mCherry coding region (mCherry).

(Johnson et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
trk
Tagged with
mCherry
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of trkN.Scer\UAS.P\T.T:Hsap\MYC,T:Disc\RFP-mCherry driven by Scer\GAL4nos.UTR.T:Hsim\VP16 results mostly in wild type embryos, though a small percentage (3%) show weak terminal patterning defects (loss of posterior filzkorper).

      (Johnson et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Fur1GL01340 or Fur2GLC01802 significantly enhances terminal patterning defects in Scer\GAL4nos.UTR.T:Hsim\VP16>trkN.Scer\UAS.P\T.T:Hsap\MYC,T:Disc\RFP-mCherry larvae.

      (Johnson et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      trkN.Scer\UAS.P\T.T:Hsap\MYC,T:Disc\RFP-mCherry
      trkN.UASp.Tag:MYC,mCherry
      Name Synonyms
      Secondary FlyBase IDs
        References (1)