FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Kr.PM
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General Information
Symbol
Scer\GAL4Kr.PM
Species
S. cerevisiae
Name
Kruppel promoter construct of Micklem
FlyBase ID
FBal0040475
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Kr-Gal4, Kruppel-Gal4, Krgal4, Kruppel::GAL4, Kruppel Gal4, P{w+mC=Kr-GAL4}
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

A 5.0kb Kr regulatory fragment controls expression of a GAL4 driver.

Allele components
Component
Use(s)
Regulatory region(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in parasegments 4-9 (T2-A4) of the embryonic ectoderm, in the amnioserosa, in the Bolwig organ and posterior spiracles in late embryos and first instar larvae, in the fat body in third instar larvae and prepupae, and in the pupal and adult abdomen. Please note that this driver has been used as a component of a fluorescently labeled balancer chromosome in many associated stocks.

Expressed in ensheathing cells but not in somatic gonadal precursors in stage 17 embryos. Stains testis pigment cells in adult males.

In embryos, expression easily scored at late extended germ band; fades during germ band retraction (stage 13-14), increases at end of embryogenesis, where it is visible in Bolwig's organ and the posterior spiracle. In larva, first instar pattern similar to that in late embryo; in second instar most conspicuous expression in the salivary glands; in late third instar and early pupae, in the fat body. In late pupae and young adults, signal observed internally throughout abdomen; in older adults restricted to internal abdominal structures near the thorax.

(Described as expressed in parasegments T2 to A4.)

In embryos, no expression observed in the CNS.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (425)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
GAL4Kr.PM
Scer\GAL4Kr.PM
Name Synonyms
Kruppel promoter construct of Micklem
Secondary FlyBase IDs
    References (88)