FB2024_03 , released June 25, 2024
Allele: Scer\GAL4He.PZ
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General Information
Symbol
Scer\GAL4He.PZ
Species
S. cerevisiae
Name
FlyBase ID
FBal0175808
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{He-GAL4.Z}
Also Known As
He-Gal4, Hemese-Gal4, hem-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Zettervall et al., 2004)
Progenitor genotype
Carried in construct
P{He-GAL4.Z}
Cytology
Description

Expression of a GAL4 driver is driven by approximately 1kb of He upstream region.

(Zettervall et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
He
He_Hemese-GAL4
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      hemocyte
      (Zettervall et al., 2004)
      larval sessile hemocyte
      (Márkus et al., 2009)
      adult stage
      hemocyte
      (Soares et al., 2014)
      Additional Information
      Statement
      Reference

      Drives expression in sessile and circulating hemocytes.

      (FlyBase Curators, 2017)

      Expression is observed in sessile and circulating hemocytes

      (Zettervall et al., 2004)
       
      Marker for
      Reflects expression of
      He
      (Soares et al., 2014, Márkus et al., 2009, Zettervall et al., 2004)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class

      abnormal cell number | larval stage, with Rac1N17.UAS

      (Zettervall et al., 2004)

      abnormal cell number | wandering third instar larval stage, with BxUAS.Tag:HA

      (Chatterjee et al., 2019)

      abnormal cell shape | larval stage, with Prosα6GD11466

      (Järvelä-Stölting et al., 2021)

      abnormal developmental rate, with upd3UAS.GFP

      (Romão et al., 2021)

      abnormal immune response, with GILT1EY03831

      (Kongton et al., 2014)

      abnormal immune response, with GILT2GD4844

      (Kongton et al., 2014)

      abnormal immune response, with GILT2KK108488

      (Kongton et al., 2014)

      abnormal immune response, with GltGD5017

      (Arefin et al., 2014)

      abnormal immune response, with NimC1RNAi.UAS

      (Kurucz et al., 2007)

      abnormal immune response, with TM9SF4UAS.cBa

      (Bergeret et al., 2008)

      abnormal immune response | adult stage, with ClC-bJF01844

      (Wong et al., 2017)

      abnormal immune response | adult stage, with ClC-bUAS.cWa

      (Wong et al., 2017)

      abnormal immune response | adult stage, with PGRP-LEHMC05031

      (Wong et al., 2017)

      abnormal immune response | adult stage, with PGRP-LEUAS.Tag:FLAG

      (Wong et al., 2017)

      abnormal immune response | adult stage, with RelHM05154

      (Wong et al., 2017)

      abnormal immune response | conditional | larval stage, with NrgGD14467

      (Williams, 2009)

      abnormal immune response | larval stage, with Mgat1RNAi.UAS.cUa

      (Mortimer et al., 2012)

      abnormal immune response | larval stage, with Mgat1UAS.cSa

      (Mortimer et al., 2012)

      abnormal immune response | larval stage, with PGRP-LEUAS.Tag:FLAG

      (Wong et al., 2017)

      abnormal immune response | larval stage, with ZirGD12624

      (Sampson et al., 2012)

      decreased cell number | larval stage, with PvrDN.UASp

      (Zettervall et al., 2004)

      decreased cell number | larval stage, with Scer\GAL4Hml.Δ, hepGD1461

      (Järvelä-Stölting et al., 2021)

      decreased cell number | third instar larval stage, with rprUAS.C

      (Yang et al., 2019)

      decreased cell number | wandering third instar larval stage, with BxGD1385

      (Chatterjee et al., 2019)

      decreased cell number | wandering third instar larval stage, with pnrUAS.cHa

      (Chatterjee et al., 2019)

      fertile, with heixHMC03335

      (Xia et al., 2015)

      increased cell death, with Ivir\M2H37A.UAS

      (Lam et al., 2010)

      increased cell number | larval stage, with Alkact.UAS.Tag:HA

      (Zettervall et al., 2004)

      increased cell number | larval stage, with AlkUAS.cLa

      (Zettervall et al., 2004)

      increased cell number | larval stage, with aopACT.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with EgfrUAS.cBa

      (Zettervall et al., 2004)

      increased cell number | larval stage, with hepCA.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with hopTum.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with IBINUAS.cVa

      (Valanne et al., 2019)

      increased cell number | larval stage, with panΔN.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with pntP1.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      increased cell number | larval stage, with Prosα6KK107987, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      increased cell number | larval stage, with Pvrλ.UASp.Tag:MYC

      (Zettervall et al., 2004)

      increased cell number | larval stage, with Rac1UAS.cLa

      (Zettervall et al., 2004)

      increased cell number | larval stage, with Ras85DV12.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with sggS9A.UAS

      (Zettervall et al., 2004)

      increased cell number | larval stage, with Tl10b.UAS

      (Zettervall et al., 2004)

      increased cell number | wandering third instar larval stage, with pnrD4.UAS

      (Chatterjee et al., 2019)

      increased cell number | wandering third instar larval stage, with pnrHMS01136

      (Chatterjee et al., 2019)

      lethal, with NijAUAS.cBa

      (Broderick et al., 2012)

      lethal, with Rac1V12.UAS

      (Zettervall et al., 2004)

      lethal - all die before end of pupal stage, with TM9SF4UAS.cBa

      (Bergeret et al., 2008)

      melanotic mass phenotype, with PPO3UAS.cNa

      (Nam et al., 2008)

      melanotic mass phenotype | third instar larval stage, with Ivir\M2H37A.UAS

      (Lam et al., 2010)

      melanotic necrosis | larval stage, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      melanotic necrosis | larval stage, with Prosα6KK107987, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      melanotic necrosis | P-stage, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      melanotic necrosis | P-stage, with Prosα6KK107987, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      partially lethal, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      short lived, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      short lived | conditional, with GltGD5017

      (Arefin et al., 2014)

      some die during P-stage, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      some die during pupal stage, with TM9SF4UAS.cBa

      (Bergeret et al., 2008)

      viable, with Acox1N250S.UAS

      (Chung et al., 2020)

      viable, with fonUAS.EGFP

      (Lindgren et al., 2008)

      viable, with heixHMC03335

      (Xia et al., 2015)

      viable, with LamUAS.cMAa

      (Muñoz-Alarcón et al., 2007)
      Phenotype Manifest In

      embryonic/larval crystal cell, with aopACT.UAS

      (Zettervall et al., 2004)

      embryonic/larval crystal cell, with heixHMC03335

      (Xia et al., 2015)

      embryonic/larval crystal cell, with Rac1N17.UAS

      (Zettervall et al., 2004)

      embryonic/larval crystal cell, with sggS9A.UAS

      (Zettervall et al., 2004)

      embryonic/larval crystal cell, with Tl10b.UAS

      (Zettervall et al., 2004)

      embryonic/larval crystal cell | increased number | wandering third instar larval stage, with BxUAS.Tag:HA

      (Chatterjee et al., 2019)

      embryonic/larval crystal cell | increased number | wandering third instar larval stage, with pnrD4.UAS

      (Chatterjee et al., 2019)

      embryonic/larval crystal cell | increased number | wandering third instar larval stage, with pnrHMS01136

      (Chatterjee et al., 2019)

      embryonic/larval crystal cell | wandering third instar larval stage, with BxGD1385

      (Chatterjee et al., 2019)

      embryonic/larval crystal cell | wandering third instar larval stage, with pnrUAS.cHa

      (Chatterjee et al., 2019)

      embryonic/larval hemocyte, with Elp3NIG.15433R

      (Walker et al., 2011)

      embryonic/larval hemocyte | decreased number | larval stage, with Scer\GAL4Hml.Δ, hepGD1461

      (Järvelä-Stölting et al., 2021)

      embryonic/larval hemocyte | decreased number | third instar larval stage, with XkrGD15912

      (Shiomi et al., 2021)

      embryonic/larval hemocyte | decreased number | third instar larval stage, with XkrHMC04978

      (Shiomi et al., 2021)

      embryonic/larval hemocyte | increased number | larval stage, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      embryonic/larval hemocyte | increased number | larval stage, with Prosα6KK107987, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      embryonic/larval hemocyte | larval stage, with IBINUAS.cVa

      (Valanne et al., 2019)

      embryonic/larval hemocyte | larval stage, with Prosα6GD11466

      (Järvelä-Stölting et al., 2021)

      embryonic/larval hemocyte | third instar larval stage, with Ivir\M2H37A.UAS

      (Lam et al., 2010)

      embryonic/larval hemocyte | third instar larval stage, with rprUAS.C

      (Yang et al., 2019)

      embryonic/larval hemocyte | third instar larval stage, with XkrGD15912

      (Shiomi et al., 2021)

      embryonic/larval hemocyte | third instar larval stage, with XkrHMC04978

      (Shiomi et al., 2021)

      embryonic/larval hemocyte | wandering third instar larval stage, with BxUAS.Tag:HA

      (Chatterjee et al., 2019)

      embryonic/larval hemolymph | third instar larval stage, with BacA\p35UAS.cHa

      (Bidla et al., 2007)

      embryonic/larval hemolymph | third instar larval stage, with egrUAS.cIa

      (Bidla et al., 2007)

      embryonic/larval hemolymph | third instar larval stage, with grimUAS.cNa

      (Bidla et al., 2007)

      embryonic/larval hemolymph | third instar larval stage, with Rho1V14.UAS

      (Bidla et al., 2007)

      embryonic/larval plasmatocyte | larval stage, with PGRP-LEUAS.Tag:FLAG

      (Wong et al., 2017)

      embryonic/larval salivary gland | third instar larval stage, with Ivir\M2H37A.UAS

      (Lam et al., 2010)

      endolysosome, with 14-3-3ζUAS.cUa

      (Pueyo et al., 2016)

      endolysosome, with mtmRNAi.cVa.UAS

      (Pueyo et al., 2016)

      endolysosome, with Pi3K68DUAS.mCherry

      (Pueyo et al., 2016)

      hemocyte, with 14-3-3ζUAS.cUa

      (Pueyo et al., 2016)

      hemocyte, with Alkact.UAS.Tag:HA

      (Zettervall et al., 2004)

      hemocyte, with AlkUAS.cLa

      (Zettervall et al., 2004)

      hemocyte, with aopACT.UAS

      (Zettervall et al., 2004)

      hemocyte, with EgfrUAS.cBa

      (Zettervall et al., 2004)

      hemocyte, with mtmRNAi.cVa.UAS

      (Pueyo et al., 2016)

      hemocyte, with panΔN.UAS

      (Zettervall et al., 2004)

      hemocyte, with Pi3K68DUAS.mCherry

      (Pueyo et al., 2016)

      hemocyte, with pntP1.UAS

      (Zettervall et al., 2004)

      hemocyte, with PvrDN.UASp

      (Zettervall et al., 2004)

      hemocyte, with Pvrλ.UASp.Tag:MYC

      (Zettervall et al., 2004)

      hemocyte, with Rac1N17.UAS

      (Zettervall et al., 2004)

      hemocyte, with Rac1UAS.cLa

      (Zettervall et al., 2004)

      hemocyte, with Ras85DV12.UAS

      (Zettervall et al., 2004)

      hemocyte, with Tl10b.UAS

      (Zettervall et al., 2004)

      hemocyte | larval stage, with mTorGL00156

      (Tran et al., 2013)

      hemocyte | larval stage, with PvrDN.UASp

      (Tran et al., 2013)

      hemocyte | larval stage, with PvrKK101575

      (Tran et al., 2013)

      hemocyte | larval stage, with PvrNIG.8222R

      (Tran et al., 2013)

      hemocyte | larval stage, with Pvrλ.UASp.Tag:MYC

      (Tran et al., 2013)

      lamellocyte, with AlkUAS.cLa

      (Zettervall et al., 2004)

      lamellocyte, with aopACT.UAS

      (Zettervall et al., 2004)

      lamellocyte, with hepCA.UAS

      (Zettervall et al., 2004)

      lamellocyte, with hopTum.UAS

      (Zettervall et al., 2004)

      lamellocyte, with panΔN.UAS

      (Zettervall et al., 2004)

      lamellocyte, with Pvrλ.UASp.Tag:MYC

      (Zettervall et al., 2004)

      lamellocyte, with Rac1N17.UAS

      (Zettervall et al., 2004)

      lamellocyte, with Rac1UAS.cLa

      (Zettervall et al., 2004)

      lamellocyte, with sggS9A.UAS

      (Zettervall et al., 2004)

      lamellocyte, with Tl10b.UAS

      (Zettervall et al., 2004)

      lamellocyte | increased number | larval stage, with Prosα6GD11466, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      lamellocyte | increased number | larval stage, with Prosα6KK107987, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      lamellocyte | increased number | larval stage, with Scer\GAL4Hml.Δ, Stat92EGD4492

      (Järvelä-Stölting et al., 2021)

      melanotic mass, with aopACT.UAS

      (Zettervall et al., 2004)

      melanotic mass, with hepCA.UAS

      (Zettervall et al., 2004)

      melanotic mass, with hopTum.UAS

      (Zettervall et al., 2004)

      melanotic mass, with panΔN.UAS

      (Zettervall et al., 2004)

      melanotic mass, with pntP1.UAS

      (Zettervall et al., 2004)

      melanotic mass, with PPO3UAS.cNa

      (Nam et al., 2008)

      melanotic mass, with Pvrλ.UASp.Tag:MYC

      (Zettervall et al., 2004)

      melanotic mass, with Rac1UAS.cLa

      (Zettervall et al., 2004)

      melanotic mass, with Ras85DV12.UAS

      (Zettervall et al., 2004)

      melanotic mass, with sggS9A.UAS

      (Zettervall et al., 2004)

      melanotic mass, with Tl10b.UAS

      (Zettervall et al., 2004)

      plasma membrane | third instar larval stage, with XkrGD15912

      (Shiomi et al., 2021)

      plasma membrane | third instar larval stage, with XkrHMC04978

      (Shiomi et al., 2021)

      secondary lobe of embryonic/larval lymph gland, with heixHMC03335

      (Xia et al., 2015)

      vacuole, with 14-3-3ζUAS.cUa

      (Pueyo et al., 2016)
      Detailed Description
      Statement
      Reference

      Depletion of He-positive cells, by expressing rprUAS.C under the control of Scer\GAL4He.PZ leads to hematopoiesis defects, as shown by the severe decrease in the number of hemocytes in third instar larvae.

      (Yang et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Suppressed by
      NOT suppressed by
      Enhancer of
      NOT Enhancer of
      Suppressor of
      Statement
      Reference

      bskHMC03539/Scer\GAL4He.PZ is a suppressor of abnormal cell migration | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      bskJF01275/Scer\GAL4He.PZ is a suppressor of abnormal cell migration | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      Scer\GAL4He.PZ/Mmp1KK108894 is a suppressor of abnormal cell migration | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      Mmp2HMJ23143/Scer\GAL4He.PZ is a suppressor of abnormal cell migration | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      bskHMC03539/Scer\GAL4He.PZ is a suppressor of abnormal cell adhesion | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      bskJF01275/Scer\GAL4He.PZ is a suppressor of abnormal cell adhesion | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      Scer\GAL4He.PZ/Mmp1KK108894 is a suppressor of abnormal cell adhesion | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      Mmp2HMJ23143/Scer\GAL4He.PZ is a suppressor of abnormal cell adhesion | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      Scer\GAL4He.PZ/DuoxUAS.cHa is a suppressor | partially of hyperplasia | larval stage phenotype of mxc1

      (Kinoshita et al., 2022)

      pnrUAS.cHa, Scer\GAL4He.PZ is a suppressor of increased cell number | wandering third instar larval stage phenotype of BxUAS.Tag:HA, Scer\GAL4He.PZ

      (Chatterjee et al., 2019)

      rprUAS.C/Scer\GAL4He.PZ is a suppressor of increased cell number | larval stage phenotype of Ras85DV12.UAS, Scer\GAL4ap-md544, scribKK101128

      (Muzzopappa et al., 2017)

      rprUAS.C/Scer\GAL4He.PZ is a suppressor of increased cell number | larval stage phenotype of BacA\p35UAS.cHa, Bub3GD9924, Scer\GAL4ap-md544

      (Muzzopappa et al., 2017)

      PGRP-LEUAS.Tag:FLAG/Scer\GAL4He.PZ is a suppressor of abnormal immune response | recessive | adult stage phenotype of ClC-b1

      (Wong et al., 2017)

      Rel68.UAS.Tag:FLAG/Scer\GAL4He.PZ is a suppressor | partially of abnormal immune response | recessive | adult stage phenotype of ClC-b1

      (Wong et al., 2017)

      PvrKK101575/Scer\GAL4He.PZ is a suppressor of increased cell number | larval stage phenotype of dlg1A40.2

      (Parisi et al., 2014)

      PPO1UAS.cNa/Scer\GAL4He.PZ is a suppressor of short lived | conditional phenotype of PPO1Bc

      (Nam et al., 2012)

      Scer\GAL4He.PZ/Cdc42V12.UAS is a suppressor of abnormal immune response | recessive | larval stage phenotype of ZirBG00267

      (Sampson et al., 2012)

      Rac2UAS.cARa/Scer\GAL4He.PZ is a suppressor of abnormal immune response | recessive | larval stage phenotype of ZirBG00267

      (Sampson et al., 2012)

      dlUASp.cMa, Scer\GAL4He.PZ, dl1 is a suppressor of lethal | larval stage phenotype of Dif1

      (Matova and Anderson, 2006)
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4Hml.Δ, hepGD1461, Scer\GAL4He.PZ is a non-suppressor of increased cell number | larval stage phenotype of Prosα6GD11466, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      Scer\GAL4Hml.Δ, Stat92EGD4492, Scer\GAL4He.PZ is a non-suppressor of increased cell number | larval stage phenotype of Prosα6GD11466, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      BxUAS.Tag:HA, Scer\GAL4He.PZ is a non-suppressor of decreased cell number | wandering third instar larval stage phenotype of Scer\GAL4He.PZ, pnrUAS.cHa

      (Chatterjee et al., 2019)

      Rab11QL.UAS/Scer\GAL4He.PZ is a non-suppressor of lethal - all die before end of P-stage phenotype of OcrlΔ3

      (Del Signore et al., 2017)

      Rab7T22N.UASp.YFP/Scer\GAL4He.PZ is a non-suppressor of lethal - all die before end of P-stage phenotype of OcrlΔ3

      (Del Signore et al., 2017)

      rprUAS.C, rprlexAop.cSa, Ecol\lexAGMR15B03, Scer\GAL4He.PZ is a non-suppressor of neoplasia | larval stage phenotype of Ras85DV12.UAS, Scer\GAL4hh.PU, dlg1GD4689

      (Muzzopappa et al., 2017)

      rprUAS.C/Scer\GAL4He.PZ is a non-suppressor of neoplasia | larval stage phenotype of Ras85DV12.UAS, Scer\GAL4ap-md544, scribKK101128

      (Muzzopappa et al., 2017)

      rprUAS.C/Scer\GAL4He.PZ is a non-suppressor of neoplasia | larval stage phenotype of BacA\p35UAS.cHa, Bub3GD9924, Scer\GAL4ap-md544

      (Muzzopappa et al., 2017)

      PGRP-LEUAS.Tag:FLAG/Scer\GAL4He.PZ, RelE20/RelE20 is a non-suppressor of abnormal immune response | recessive | adult stage phenotype of ClC-b1

      (Wong et al., 2017)

      Scer\GAL4He.PZ/RelHM05154 is a non-suppressor of abnormal immune response | recessive | adult stage phenotype of ClC-b1

      (Wong et al., 2017)

      Scer\GAL4He.PZ/BacA\p35UAS.cHa is a non-suppressor of abnormal immune response | recessive | adult stage phenotype of ClC-b1

      (Wong et al., 2017)

      Prx2RNAi.UAS/Scer\GAL4He.PZ is a non-suppressor of short lived | conditional phenotype of Hayan1

      (Nam et al., 2012)

      IrcRNAi.UAS/Scer\GAL4He.PZ is a non-suppressor of short lived | conditional phenotype of Hayan1

      (Nam et al., 2012)

      Mmus\BaxUAS.cGa/Scer\GAL4He.PZ is a non-suppressor of melanotic mass phenotype | larval stage | nutrition conditional phenotype of MAPk-Ak2Δ43

      (Seisenbacher et al., 2011)
      Phenotype Manifest In
      NOT Enhanced by
      Suppressed by
      Statement
      Reference

      Prosα6GD11466, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ has lamellocyte | increased number | larval stage phenotype, suppressible | partially by hepGD1461, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      Prosα6GD11466, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ has lamellocyte | increased number | larval stage phenotype, suppressible | partially by Stat92EGD4492, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      BxUAS.Tag:HA, Scer\GAL4He.PZ has embryonic/larval crystal cell | increased number | wandering third instar larval stage phenotype, suppressible by pnrUAS.cHa, Scer\GAL4He.PZ

      (Chatterjee et al., 2019)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has endolysosome phenotype, suppressible by Pi3K68DGL00159, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has hemocyte phenotype, suppressible by Pi3K68DGL00159, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has hemocyte phenotype, suppressible by hemoUAS.FL, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has vacuole phenotype, suppressible by hemoUAS.FL, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has endolysosome phenotype, suppressible by hemoUAS.FL, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has hemocyte phenotype, suppressible by Hsap\SNNUASp.cPa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζUAS.cUa, Scer\GAL4He.PZ has vacuole phenotype, suppressible by Hsap\SNNUASp.cPa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Scer\GAL4He.PZ, mtmRNAi.cVa.UAS has hemocyte phenotype, suppressible by 14-3-3ζGD16467, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Scer\GAL4He.PZ, mtmRNAi.cVa.UAS has endolysosome phenotype, suppressible by 14-3-3ζGD16467, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Pi3K68DUAS.mCherry, Scer\GAL4He.PZ has hemocyte phenotype, suppressible by hemoUAS.FL, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Pi3K68DUAS.mCherry, Scer\GAL4He.PZ has endolysosome phenotype, suppressible by hemoUAS.FL, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Pi3K68DUAS.mCherry, Scer\GAL4He.PZ has hemocyte phenotype, suppressible by 14-3-3ζGD16467, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Pi3K68DUAS.mCherry, Scer\GAL4He.PZ has endolysosome phenotype, suppressible by 14-3-3ζGD16467, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Scer\GAL4He.PZ, grimUAS.cNa has embryonic/larval hemolymph | third instar larval stage phenotype, suppressible by Spn27AUAS.cLa/Scer\GAL4He.PZ

      (Bidla et al., 2007)
      NOT suppressed by
      Enhancer of
      NOT Enhancer of
      Suppressor of
      Statement
      Reference

      bskHMC03539/Scer\GAL4He.PZ is a suppressor of larval circulating hemocyte | ectopic | increased number phenotype of mxc1

      (Takarada et al., 2023)

      bskJF01275/Scer\GAL4He.PZ is a suppressor of larval circulating hemocyte | ectopic | increased number phenotype of mxc1

      (Takarada et al., 2023)

      Scer\GAL4He.PZ/Mmp1KK108894 is a suppressor of larval circulating hemocyte | ectopic | increased number phenotype of mxc1

      (Takarada et al., 2023)

      Mmp2HMJ23143/Scer\GAL4He.PZ is a suppressor of larval circulating hemocyte | ectopic | increased number phenotype of mxc1

      (Takarada et al., 2023)

      hepGL00089/Scer\GAL4He.PZ is a suppressor of pseudopodium | increased number | larval stage phenotype of mxc1

      (Takarada et al., 2023)

      Scer\GAL4He.PZ/DuoxUAS.cHa is a suppressor | partially of embryonic/larval lymph gland | larval stage phenotype of mxc1

      (Kinoshita et al., 2022)

      Scer\GAL4Hml.Δ, hepGD1461, Scer\GAL4He.PZ is a suppressor | partially of lamellocyte | increased number | larval stage phenotype of Prosα6GD11466, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      Scer\GAL4Hml.Δ, Stat92EGD4492, Scer\GAL4He.PZ is a suppressor | partially of lamellocyte | increased number | larval stage phenotype of Prosα6GD11466, Scer\GAL4He.PZ, Scer\GAL4Hml.Δ

      (Järvelä-Stölting et al., 2021)

      pnrUAS.cHa, Scer\GAL4He.PZ is a suppressor of embryonic/larval crystal cell | increased number | wandering third instar larval stage phenotype of BxUAS.Tag:HA, Scer\GAL4He.PZ

      (Chatterjee et al., 2019)

      Rab11QL.UAS/Scer\GAL4He.PZ is a suppressor | partially of hemocyte | increased number | third instar larval stage phenotype of OcrlΔ3

      (Del Signore et al., 2017)

      Rab7T22N.UASp.YFP/Scer\GAL4He.PZ is a suppressor | partially of hemocyte | increased number | third instar larval stage phenotype of OcrlΔ3

      (Del Signore et al., 2017)

      rprUAS.C/Scer\GAL4He.PZ is a suppressor of embryonic/larval hemocyte | increased number | larval stage phenotype of Ras85DV12.UAS, Scer\GAL4ap-md544, scribKK101128

      (Muzzopappa et al., 2017)

      rprUAS.C/Scer\GAL4He.PZ is a suppressor of embryonic/larval hemocyte | increased number | larval stage phenotype of BacA\p35UAS.cHa, Bub3GD9924, Scer\GAL4ap-md544

      (Muzzopappa et al., 2017)

      PGRP-LEUAS.Tag:FLAG/Scer\GAL4He.PZ is a suppressor of embryonic/larval plasmatocyte | larval stage phenotype of ClC-b1

      (Wong et al., 2017)

      Pi3K68DGL00159, Scer\GAL4He.PZ is a suppressor of endolysosome phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Pi3K68DGL00159, Scer\GAL4He.PZ is a suppressor of hemocyte phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      hemoUAS.FL, Scer\GAL4He.PZ is a suppressor of hemocyte phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      hemoUAS.FL, Scer\GAL4He.PZ is a suppressor of vacuole phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      hemoUAS.FL, Scer\GAL4He.PZ is a suppressor of endolysosome phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Hsap\SNNUASp.cPa, Scer\GAL4He.PZ is a suppressor of hemocyte phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      Hsap\SNNUASp.cPa, Scer\GAL4He.PZ is a suppressor of vacuole phenotype of 14-3-3ζUAS.cUa, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζGD16467, Scer\GAL4He.PZ is a suppressor of hemocyte phenotype of Scer\GAL4He.PZ, mtmRNAi.cVa.UAS

      (Pueyo et al., 2016)

      14-3-3ζGD16467, Scer\GAL4He.PZ is a suppressor of endolysosome phenotype of Scer\GAL4He.PZ, mtmRNAi.cVa.UAS

      (Pueyo et al., 2016)

      hemoUAS.FL, Scer\GAL4He.PZ is a suppressor of hemocyte phenotype of Pi3K68DUAS.mCherry, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      hemoUAS.FL, Scer\GAL4He.PZ is a suppressor of endolysosome phenotype of Pi3K68DUAS.mCherry, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζGD16467, Scer\GAL4He.PZ is a suppressor of hemocyte phenotype of Pi3K68DUAS.mCherry, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      14-3-3ζGD16467, Scer\GAL4He.PZ is a suppressor of endolysosome phenotype of Pi3K68DUAS.mCherry, Scer\GAL4He.PZ

      (Pueyo et al., 2016)

      PvrKK101575/Scer\GAL4He.PZ is a suppressor of embryonic/larval hemocyte | larval stage phenotype of dlg1A40.2

      (Parisi et al., 2014)

      Spn27AUAS.cLa/Scer\GAL4He.PZ is a suppressor of embryonic/larval hemolymph | third instar larval stage phenotype of Scer\GAL4He.PZ, grimUAS.cNa

      (Bidla et al., 2007)

      dlUASp.cMa, Scer\GAL4He.PZ, dl1 is a suppressor of hemocyte phenotype of Dif1

      (Matova and Anderson, 2006)

      dlUASp.cMa, Scer\GAL4He.PZ, dl1 is a suppressor of hemolymph phenotype of Dif1

      (Matova and Anderson, 2006)
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The co-expression of Ras85DV12.UAS and scribKK101128 under the control of Scer\GAL4ap-md544 induces wing disc neoplasia which, when transplanted, can form solid tumors in the host; in both wing discs and allografts, there is amplification of the resident myoblast population, as well as accumulation of circulating hemocytes. The same tumor induction and hemocyte recruitment occurs if expression is only induced in wing disc transplants (expression induction is controlled by Gal80[ts] and temperature-shift); hemocyte ablation on the host (by expressing rprUAS.C under the control of Scer\GAL4He.PZ) does not suppress the tumor-like growth.

      (Muzzopappa et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      BxGD1385/Scer\GAL4He.PZ rescues BxJ

      (Chatterjee et al., 2019)

      OcrlUAS.GFP/Scer\GAL4He.PZ rescues OcrlΔ3

      (Del Signore et al., 2017)

      OcrlUAS.GFP/Scer\GAL4He.PZ rescues OcrlΔ4

      (Del Signore et al., 2017)

      ClC-bUAS.cWa/Scer\GAL4He.PZ rescues ClC-b1

      (Wong et al., 2017)

      PGRP-LEUAS.Tag:FLAG/Scer\GAL4He.PZ rescues PGRP-LE112

      (Wong et al., 2017)

      Scer\GAL4He.PZ/hemoUAS.ORF rescues hemo-A4

      (Pueyo et al., 2016)

      hemoUAS.FL.GFP/Scer\GAL4He.PZ rescues hemo-A4

      (Pueyo et al., 2016)

      hemoUAS.FL/Scer\GAL4He.PZ rescues hemo-A4

      (Pueyo et al., 2016)

      HayanUAS.cNa/Scer\GAL4He.PZ rescues Hayan1

      (Nam et al., 2012)

      Cyt-b5UAS.cKa/Scer\GAL4He.PZ rescues Cyt-b5k09716/Cyt-b5k14202

      (Kleinhesselink et al., 2011)

      Cyt-b5UAS.cKa/Scer\GAL4He.PZ rescues [+]/Cyt-b5unspecified

      (Kleinhesselink et al., 2011)

      egrUAS.cIa/Scer\GAL4He.PZ rescues egr1

      (Bidla et al., 2007)
      Partially rescues

      BxGD1385/Scer\GAL4He.PZ partially rescues Bx1

      (Chatterjee et al., 2019)

      OcrlUAS.GFP/Scer\GAL4He.PZ partially rescues OcrlΔ3

      (Del Signore et al., 2017)

      Scer\GAL4He.PZ/Ocrlcat.UASp.mCherry.CRY2(PHR) partially rescues OcrlΔ3

      (Del Signore et al., 2017)

      Scer\GAL4He.PZ/ClC-bunc.UAS.Tag:MYC partially rescues ClC-b1

      (Wong et al., 2017)
      Fails to rescue

      Scer\GAL4He.PZ/OcrlH469R.UAS.GFP fails to rescue OcrlΔ3

      (Del Signore et al., 2017)

      ClC-btd.UAS.Tag:MYC/Scer\GAL4He.PZ fails to rescue ClC-b1

      (Wong et al., 2017)

      hemoFS.UAS/Scer\GAL4He.PZ fails to rescue hemo-A4

      (Pueyo et al., 2016)

      Cyt-b5UAS.cKa/Scer\GAL4He.PZ fails to rescue Df(2R)ST1/Cyt-b5k14202

      (Kleinhesselink et al., 2011)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4He.PZ
      Name Synonyms
      Secondary FlyBase IDs
        References (61)