FB2024_03 , released June 25, 2024
Allele: Dmel\OcrlΔ4
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General Information
Symbol
Dmel\OcrlΔ4
Species
D. melanogaster
Name
FlyBase ID
FBal0336685
Feature type
allele
Associated gene
Dmel\Ocrl
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Del Signore et al., 2017)
Progenitor genotype
P{EPgy2}OcrlEY15890
(Del Signore et al., 2017)
Cytology
Description

2973bp deletion within Ocrl.

(Del Signore et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:1,923,033..1,926,006 [+]
Comment:

A 2974 bp deletion resulting from the imprecise excision of P{EPgy2}OcrlEY15890 reported at X:1 ,817,066..1,820,039 in R5 coordinates.

(Del Signore et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      OcrlΔ4 larvae show a dramatic increase in the number of circulating hemocytes compared to controls and frequently display large melanotic masses in their posterior body cavity.

      (Del Signore et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      OcrlΔ4 is rescued by OcrlUAS.GFP/Scer\GAL4He.PZ

      (Del Signore et al., 2017)
      Comments

      The dramatic increase in the number of circulating hemocytes observed in OcrlΔ4 mutant larvae can be rescued by Scer\GAL4He.PZ-driven expression of OcrlScer\UAS.T:Avic\GFP.

      (Del Signore et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      OcrlΔ4
      docrlΔ4
      (Del Signore et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)