UASt regulatory sequences drive expression of an inverted repeat.
eye | adult stage, with Scer\GAL4Hml.Δ
Adult flies expressing PvrKK101575 RNAi under the control of Scer\GAL4Hml.Δ show more extensive eye degeneration upon exposure of one eye to UV irradiation during pupal stage compared to wild-type.
Scer\GAL4He.PZ-mediated expression of PvrKK101575 markedly downregulates hemocyte counts in larvae.
PvrKK101575, Scer\GAL4Hml.Δ has abnormal stress response | adult stage phenotype, suppressible by ManfUAS.cPa, Scer\GAL4Hml.Δ
PvrKK101575, Scer\GAL4Hml.Δ has visible | adult stage phenotype, suppressible by ManfUAS.cPa, Scer\GAL4Hml.Δ
Scer\GAL4Hml.Δ/PvrKK101575 is an enhancer of neoplasia | larval stage phenotype of dlg1A40.2
Scer\GAL4Hml.Δ/PvrKK101575 is a suppressor of increased cell number | larval stage phenotype of dlg1A40.2
PvrKK101575/Scer\GAL4He.PZ is a suppressor of increased cell number | larval stage phenotype of dlg1A40.2
PvrKK101575, Scer\GAL4Hml.Δ, dlg1A40.2 has decreased cell death | larval stage phenotype
PvrKK101575, Scer\GAL4Hml.Δ has eye | adult stage phenotype, suppressible by ManfUAS.cPa, Scer\GAL4Hml.Δ
Scer\GAL4Hml.Δ/PvrKK101575 is an enhancer of wing disc phenotype of dlg1A40.2
Scer\GAL4Hml.Δ/PvrKK101575 is a suppressor of embryonic/larval hemocyte | larval stage phenotype of dlg1A40.2
PvrKK101575/Scer\GAL4He.PZ is a suppressor of embryonic/larval hemocyte | larval stage phenotype of dlg1A40.2
PvrKK101575, Scer\GAL4Hml.Δ, dlg1A40.2 has wing disc phenotype
The increased level of eye tissue degeneration upon UV irradiation (administered during pupal stage) characteristic for adult flies expressing PvrKK101575 under the control of Scer\GAL4Hml.Δ can be rescued by co-expression of ManfScer\UAS.cPa.
The apoptosis observed in dlg1A40.2 mutant wing disc tumors is virtually abrogated by the expression of PvrKK101575 under the control of the Scer\GAL4Hml.Δ driver.