lincRNA.927
semaphorin domain protein, semaphorin receptor - involved in axon guidance - Semaphorin 2a secreted by oenocytes signals through plexin B and plexin A to guide sensory axons in the Drosophila embryo
Please see the JBrowse view of Dmel\PlexA for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.41
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
7.5 (northern blot)
1945 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\PlexA using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
plexA transcripts are broadly distributed during early embryogenesis. Starting at the extended germ band stage, expression is strong in the CNS but is reduced elsewhere. After stage 15, transcripts are mainly restricted to the CNS where they are found in many neurons. Expression is also observed in myoblasts but does not persist in muscle fibers.
JBrowse - Visual display of RNA-Seq signals
View Dmel\PlexA in JBrowse4-0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
PlexA functions cell autonomously in guiding the lateral cluster and v'ch1 axons.
plexA controls motor and central nervous system axon guidance in the embryo.
Source for merge of: plexA BcDNA:GM05237
Source for merge of plexA BcDNA:GM05237 was a shared cDNA ( date:030728 ).
Source for identity of: PlexA plexA