FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
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General Information
Term GTPase activator activity ID (Ontology) GO:0005096 (Gene Ontology)
Definition Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
Also Known As "GAP activity"
Comment
Links to Extrernal Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      84
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 GTPase activator activity (all annotations which use CV term, excluding "NOT" statements)       9     84
     contributes_to | GTPase activator activity       --       6
     enables | GTPase activator activity       --      80
 NOT | enables | GTPase activator activity       --       1
Spanning Tree (Parents/Children)
Only view relationship: 
enzyme regulator activity
 |__enzyme activator activity_________________
nucleoside-triphosphatase regulator activity  |
 |__GTPase regulator activity_________________|
molecular function activator activity         |
 |__enzyme activator activity_________________|
                                              GTPase activator activity  93 rec.
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Is a enzyme activator activity
GTPase regulator activity
Part of
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Synonyms
  • "ARF GAP activity" NARROW
    "ARF GTPase activator activity" NARROW
    "GAP activity" EXACT
    "Rab GAP activity" NARROW
    "Rab GTPase activator activity" NARROW
    "Rac GAP activity" NARROW
    "Rac GTPase activator activity" NARROW
    "Ral GAP activity" NARROW
    "Ral GTPase activator activity" NARROW
    "Ran GAP activity" NARROW
    "Ran GTPase activator activity" NARROW
    "RanGAP" NARROW
    "Rap GAP activity" NARROW
    "Rap GTPase activator activity" NARROW
    "Ras GAP activity" NARROW
    "Ras GTPase activator activity" NARROW
    "Rho GAP activity" NARROW
    "Rho GTPase activator activity" NARROW
    "Sar GAP activity" NARROW
    "Sar GTPase activator activity" NARROW
Secondary IDs
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Reactome:R-HSA-392513 "Rap1 signal termination by Rap1GAPs"
Reactome:R-HSA-399935 "Inactivation of R-Ras by Sema3A-Plexin-A GAP activity"
Reactome:R-HSA-4093339 "p120-RasGAP activates GTP hydrolysis on RAS, inactivating it"
Reactome:R-HSA-416546 "Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity"
Reactome:R-HSA-416559 "Inactivation of Rho-GTP by p190RhoGAP"
Reactome:R-HSA-428522 "Inactivation of RAC1"
Reactome:R-HSA-428533 "Inactivation of CDC42"
Reactome:R-HSA-5638007 "RP2 activates the GTPase activity of ARL3"
Reactome:R-HSA-8981637 "RHOA GAPs stimulate RHOA GTPase activity"
Reactome:R-HSA-8985594 "MYO9B inactivates RHOA"
Reactome:R-HSA-9013022 "RHOB GAPs stimulate RHOB GTPase activity"
Reactome:R-HSA-9013111 "RHOC GAPs stimulate RHOC GTPase activity"
Reactome:R-HSA-9013144 "RAC1 GAPs stimulate RAC1 GTPase activity"
Reactome:R-HSA-9013161 "CDC42 GAPs stimulate CDC42 GTPase activity"
Reactome:R-HSA-9013437 "RHOD GAPs stimulate RHOD GTPase activity"
Reactome:R-HSA-9014295 "RAC2 GAPs stimulate RAC2 GTPase activity"
Reactome:R-HSA-9014434 "RHOG GAPs stimulate RHOG GTPase activity"
Reactome:R-HSA-9017488 "RHOJ GAPs stimulate RHOJ GTPase activity"
Reactome:R-HSA-9018745 "RHOQ GAPs stimulate RHOQ GTPase activity"
Reactome:R-HSA-9018806 "RAC3 GAPs stimulate RAC3 GTPase activity"
Reactome:R-HSA-9624893 "RAN stimulates fusion of nuclear envelope (NE) membranes"
Reactome:R-HSA-9693282 "RHOF GAPs stimulate RHOF GTPase activity"