FB2024_02 , released April 23, 2024
Gene Group: PLEXINS
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General Information
Name
PLEXINS
Species
D. melanogaster
Symbol
PLXN
FlyBase ID
FBgg0000718
Date last reviewed
2017-03-21
Number of members
2
Description
Description
The Plexins are transmembrane axon guidance proteins that serve as receptors for semaphorins. (Adapted from FBrf0208160).
Notes on Group

In Drosophila, PlexA binds strongly to Sema1a and Sema1b and mediates the Sema-dependent repulsion of embryonic motor axons, while PlexB binds Sema2a and mediates the Sema2a-dependent repulsion of motor and sensory axons (FBrf0208160).

Source Material
The PLEXINS Gene Group has been compiled using the following publication(s): Zlatic et al., 2009, Bates and Whitington, 2007, Ayoob et al., 2006, Castellani and Rougon, 2002, Terman et al., 2002, and Yu and Kolodkin, 1999 .
Key Gene Ontology (GO) terms
Molecular Function
semaphorin receptor activity
Biological Process
semaphorin-plexin signaling pathway
Cellular Component
plasma membrane
Related Gene Groups
Parent group(s)
TRANSMEMBRANE RECEPTORS
Other related group(s)
SEMAPHORINS
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
PlexA
Plexin A
lincRNA.927
(Zlatic et al., 2009, Bates and Whitington, 2007, Ayoob et al., 2006, Castellani and Rougon, 2002, Terman et al., 2002, Yu and Kolodkin, 1999)
PlexB
Plexin B
plex
(Zlatic et al., 2009, Bates and Whitington, 2007, Ayoob et al., 2006, Castellani and Rougon, 2002, Terman et al., 2002, Yu and Kolodkin, 1999)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PLXN
PLEXINS
Secondary FlyBase ID(s)
References (7)