Gene Group: SEMAPHORINS

General Information

Name

SEMAPHORINS

Species

D. melanogaster

Symbol

SEMA

FlyBase ID

FBgg0000704

Date last reviewed

2017-03-20

Number of members

Description

The Semaphorins are a family of membrane and secreted short-range signaling proteins, originally characterized for their role in axon guidance. The major signal transducing receptors for the semaphorins are the plexins. (Adapted from FBrf0233112, FBrf0137217 and PMID:23253452).

Notes on Group

Sema2a and Sema2b are sectreted proteins (FBrf0234187).

Source Material

The SEMAPHORINS Gene Group has been compiled using the following publication(s): Roh et al., 2016, Yoo et al., 2016, Emerson et al., 2013, Zlatic et al., 2009, Bates and Whitington, 2007, Ayoob et al., 2006, Yazdani and Terman, 2006, Castellani and Rougon, 2002, Bahri et al., 2001, and Yu and Kolodkin, 1999 .

Key Gene Ontology (GO) terms

Molecular Function

semaphorin receptor binding

Biological Process

semaphorin-plexin signaling pathway

Cellular Component

plasma membrane

extracellular region

Related Gene Groups

Parent group(s)

RECEPTOR LIGANDS

Other related group(s)

PLEXINS

Members (5)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Sema1a

Semaphorin 1a

Sema-1a, Sema 1a, D-SemaI, Fasciclin-IV, sema-I

(Yoo et al., 2016, Emerson et al., 2013, Zlatic et al., 2009, Bates and Whitington, 2007, Ayoob et al., 2006, Yazdani and Terman, 2006, Castellani and Rougon, 2002, Bahri et al., 2001, Yu and Kolodkin, 1999)

Sema1b

Semaphorin 1b

Sema-1b, sema-III, Sema 1b, semaphorin, semaphorin-like

(Yoo et al., 2016, Yazdani and Terman, 2006, Yu and Kolodkin, 1999)

Sema2a

Semaphorin 2a

Sema-2a, SemaII, D-SemaII, semaphorin, sema-II

(Roh et al., 2016, Yoo et al., 2016, Emerson et al., 2013, Zlatic et al., 2009, Bates and Whitington, 2007, Ayoob et al., 2006, Yazdani and Terman, 2006)

Sema2b

Semaphorin 2b

Sema-2b, semaphorin

(Roh et al., 2016, Yoo et al., 2016, Emerson et al., 2013, Bates and Whitington, 2007, Yazdani and Terman, 2006)

Sema5c

Semaphorin 5c

Sema-5c, Sema-3a, BG01245, Sema 5c, semaphorin

(Yoo et al., 2016, Yazdani and Terman, 2006, Castellani and Rougon, 2002, Bahri et al., 2001)

External Data

Equivalent Group(s)

Human Semaphorins (HGNC)

Other resource(s)