FlyBase Allele Report: Dmel\Zip42C.1[UAS.EGFP]

Expression of Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^Mef2.PU significantly rescues the faulty specification of fusion-competent myoblasts, and partially rescues the DA1 fusion defects of foi^C887/foi^C887 mutants.

(Carrasco-Rando et al., 2016)

Co-expression of Zip42C.1 and ZnT63C^KK102261 under the control of Scer\GAL4^GMR.long results in strong loss of pigmentation throughout the centre of the eye.

(Dechen et al., 2015)

Co-expression of Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} severely exacerbates the rough eye phenotype of flies expressing Zip89B^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.long.

(Richards et al., 2015)

Co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa results in eyes which are rough and have reduced pigmentation.

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is fully rescued if the flies are also co-expressing either ZnT41F^{Scer\UAS.T:Zzzz\FLAG} or ZnT35C^{Scer\UAS.T:Zzzz\FLAG}.

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is rescued if the flies are also co-expressing either ZnT77C^GD2749, ZnT86D^GD2913, Zip42C.2^GD1831, Zip89B^GD3013, Zip99C^GD370 or Catsup^KK103630.

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is partially rescued if the flies are also co-expressing either ZnT33D^{Scer\UAS.PB.T:Zzzz\FLAG} or Zip99C^{Scer\UAS.T:Zzzz\FLAG}.

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is enhanced if the flies are also co-expressing one of ZnT77C^{Scer\UAS.T:Zzzz\FLAG}, ZnT86D^{Scer\UAS.T:Zzzz\FLAG}, Zip88E^{Scer\UAS.T:Zzzz\FLAG}, Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}, foi^{Scer\UAS.T:Zzzz\FLAG} or Catsup^{Scer\UAS.T:Zzzz\FLAG}.

Co-expression of either ZnT41F^GD4522, ZnT33D^KK100432, ZnT35C^VDRC.cUa, Zip88E^VDRC.cUa or foi^GD2367 has no effect on the mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa.

Co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 results in a mild cleft in the thorax and a significant reduction in the size of the scutellum.

The thorax defects caused by co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 are rescued if the flies are also co-expressing one of ZnT41F^{Scer\UAS.T:Zzzz\FLAG}, ZnT33D^{Scer\UAS.PB.T:Zzzz\FLAG}, ZnT35C^{Scer\UAS.T:Zzzz\FLAG}, Zip99C^{Scer\UAS.T:Zzzz\FLAG} or ZnT77C^GD2749.

The thorax defects caused by co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 are enhanced if the flies are also co-expressing one of ZnT86D^{Scer\UAS.T:Zzzz\FLAG}, Zip88E^{Scer\UAS.T:Zzzz\FLAG}, foi^{Scer\UAS.T:Zzzz\FLAG}, ZnT41F^GD4522, ZnT86D^GD2913, Zip42C.2^GD1831 or Zip99C^GD370.

Co-expression of either Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}, ZnT33D^KK100432, ZnT35C^VDRC.cUa, Zip88E^VDRC.cUa, Zip89B^GD3013 or foi^GD2367 has no effect on the mutant thorax phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237.

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is rescued if the flies are also co-expressing either ZnT41F^{Scer\UAS.T:Avic\GFP-EGFP}, ZnT35C^{Scer\UAS.T:Avic\GFP-EGFP}, ZnT33D^{Scer\UAS.PB.T:Avic\GFP-EGFP} or Zip99C^{Scer\UAS.T:Avic\GFP-EGFP}.

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is enhanced if the flies are also co-expressing ZnT77C^{Scer\UAS.T:Avic\GFP-EGFP}, ZnT86D^{Scer\UAS.T:Avic\GFP-EGFP}, Zip88E^{Scer\UAS.T:Avic\GFP-EGFP}, Zip42C.2^{Scer\UAS.T:Avic\GFP-EGFP} or Catsup^{Scer\UAS.T:Avic\GFP-EGFP}.

Co-expression of foi^{Scer\UAS.T:Avic\GFP-EGFP} has no effect on the mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa.

The mutant visible phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is rescued if the flies also carry either Df(3R)ED10639, Df(2L)ED1050 or Df(2R)ED1612.

The mutant visible phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is enhanced if the flies also carry either Df(2R)BSC889, Df(3L)BSC839 or Df(3R)BSC469.

(Lye et al., 2013)

Co-expression of ZnT41F^GD4522 and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of either Scer\GAL4^GMR.PFa or Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

Co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa results in a rough eye phenotype and loss of eye pigmentation. This phenotype is enhanced in a dose-dependent manner by the addition of zinc chloride to the food medium and is suppressed in a dose-dependent manner by the addition of TPEN to the food medium.

Co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 results in scutellum loss, a thoracic cleft, loss of cuticle pigmentation and thoracic bristle misalignment. This phenotype is enhanced in a dose-dependent manner by the addition of zinc chloride to the food medium, resulting in the formation of large melanotic masses, which are primarily seen in the abdominal region. The phenotype is suppressed by the addition of TPEN to the food medium.

Co-expression of ZnT35C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of either Scer\GAL4^GMR.PFa or Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

Co-expression of ZnT77C^GD2749 and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa does not result in a mutant phenotype.

Co-expression of ZnT77C^GD2749 and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 results in sporadic abdominal cuticle defects.

Co-expression of ZnT86D^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of either Scer\GAL4^GMR.PFa or Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

Co-expression of Zip88E^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of either Scer\GAL4^GMR.PFa or Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

Co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa results in a mild rough eye phenotype.

Co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 results in a reduced scutellum, a mild thoracic cleft and abnormal thoracic bristle alignment.

Co-expression of Zip89B^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa results in a flattened eye.

Co-expression of foi^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of either Scer\GAL4^GMR.PFa or Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

Co-expression of Zip99C^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa does not result in a mutant phenotype.

Co-expression of Zip99C^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 results in abnormal thoracic bristle development.

Co-expression of Catsup^{Scer\UAS.cLa.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of either Scer\GAL4^GMR.PFa or Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

(Lye et al., 2012)

Xenogenetic Interactions

Statement

Reference

Co-expression of BacA\p35^Scer\UAS.cUa mildly exacerbates the eye defects caused by co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa.

Co-expression of BacA\p35^Scer\UAS.cUa exacerbates the thoracic midline defects caused by co-expression of ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237.

(Lye et al., 2012)

Complementation and Rescue Data

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Notes on Origin

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External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP}

Zip42C.1^UAS.EGFP

dZIP42C.1^eGFP

(Richards et al., 2015)

dZip42C.1^eGFP

(Lye et al., 2012, Lye et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (6)

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