FlyBase Allele Report: Dmel\Zip42C.2[UAS.Tag:FLAG]

General Information

Symbol

Dmel\Zip42C.2^UAS.Tag:FLAG

Species

D. melanogaster

Name

FlyBase ID

FBal0288196

Feature type

allele

Associated gene

Dmel\Zip42C.2

Associated Insertion(s)

Carried in Construct

M{UAS-Zip42C.2.flag}

Also Known As

dZip42C.2^flag, pUAST dZip42C.2^flag

Key Links

Transgenic product class

wild_type

(Lye et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Lye et al., 2012)

Mutagen

in vitro construct

(Lye et al., 2012)

Progenitor genotype

Carried in construct

M{UAS-Zip42C.2.flag}

Cytology

Description

UASt regulatory sequences drive expression of Zip42C.2 which is tagged at the C-terminal end with Tag:FLAG.

(Lye et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Zip42C.2

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during larval stage, with Scer\GAL4^Cyp6g1.HR

(Lye et al., 2012)

viable, with Scer\GAL4^Tub.PU

(Lye et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PFa does not result in a mutant phenotype.

Expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^pnr-MD237 does not result in a mutant phenotype.

(Lye et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of abnormal eye color phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of abnormal eye color phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of abnormal eye color phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of visible phenotype of Scer\GAL4^GMR.long, Zip89B^UAS.Tag:FLAG

(Richards et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.PFa is an enhancer of visible phenotype of Scer\GAL4^GMR.PFa, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

NOT Enhancer of

Statement

Reference

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^pnr-MD237 is a non-enhancer of visible phenotype of Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

NOT Suppressor of

Statement

Reference

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^pnr-MD237 is a non-suppressor of visible phenotype of Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

Other

Statement

Reference

Scer\GAL4^GMR.PFa, Zip42C.1^UAS.EGFP, Zip42C.2^UAS.Tag:FLAG has visible phenotype

(Lye et al., 2012)

Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, Zip42C.2^UAS.Tag:FLAG has visible phenotype

(Lye et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of eye phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.long is an enhancer of eye phenotype of Scer\GAL4^GMR.long, Zip89B^UAS.Tag:FLAG

(Richards et al., 2015)

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^GMR.PFa is an enhancer of eye phenotype of Scer\GAL4^GMR.PFa, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

NOT Enhancer of

Statement

Reference

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^pnr-MD237 is a non-enhancer of adult thorax phenotype of Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

NOT Suppressor of

Statement

Reference

Zip42C.2^UAS.Tag:FLAG/Scer\GAL4^pnr-MD237 is a non-suppressor of adult thorax phenotype of Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

Other

Statement

Reference

Scer\GAL4^GMR.PFa, Zip42C.1^UAS.EGFP, Zip42C.2^UAS.Tag:FLAG has eye phenotype

(Lye et al., 2012)

Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, Zip42C.2^UAS.Tag:FLAG has scutellum phenotype

(Lye et al., 2012)

Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, Zip42C.2^UAS.Tag:FLAG has chaeta phenotype

(Lye et al., 2012)

Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, Zip42C.2^UAS.Tag:FLAG has adult thorax phenotype

(Lye et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86D^Scer\UAS.cDa under the control of Scer\GAL4^GMR.long are severely exacerbated by co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}.

The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86D^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.long are severely exacerbated by co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}.

The morphological and pigmentation defects in the adult eye seen upon expression of Zip71B^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.long are strongly exacerbated by co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}.

(Dechen et al., 2015)

Co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} severely exacerbates the rough eye phenotype of flies expressing Zip89B^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.long.

(Richards et al., 2015)

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is enhanced if the flies are also co-expressing Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}.

Co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} has no effect on the mutant thorax phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237.

(Lye et al., 2013)

Co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa results in a mild rough eye phenotype.

Co-expression of Zip42C.2^{Scer\UAS.T:Zzzz\FLAG} and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^pnr-MD237 results in a reduced scutellum, a mild thoracic cleft and abnormal thoracic bristle alignment.

(Lye et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Zip42C.2^{Scer\UAS.T:Zzzz\FLAG}

Zip42C.2^UAS.Tag:FLAG

dZIP42C.2^FLAG

(Richards et al., 2015)

dZip42C.2^flag

(Lye et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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