FB2024_03 , released June 25, 2024
Allele: Dmel\foiUAS.Tag:FLAG
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General Information
Symbol
Dmel\foiUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0288198
Feature type
allele
Associated gene
Dmel\foi
Associated Insertion(s)
Carried in Construct
M{UAS-foi.flag}
Key Links
Transgenic product class
wild_type
(Lye et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lye et al., 2012)
Mutagen
in vitro construct
(Lye et al., 2012)
Progenitor genotype
Carried in construct
M{UAS-foi.flag}
Cytology
Description

UASt regulatory sequences drive expression of foi which is tagged at the C-terminal end with Tag:FLAG.

(Lye et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
foi
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of foiScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PFa does not result in a mutant phenotype.

      Expression of foiScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4pnr-MD237 does not result in a mutant phenotype.

      (Lye et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Suppressor of
      NOT Suppressor of
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are strongly exacerbated by co-expression of foiScer\UAS.T:Zzzz\FLAG, which also leads to partial lethality.

      The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86DScer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4GMR.long are strongly ameliorated by co-expression of foiScer\UAS.T:Zzzz\FLAG.

      The adult eye phenotype seen upon expression of Zip71BScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.long can be partially modified by co-expression of foiScer\UAS.T:Zzzz\FLAG : the morphological defects are strongly worsened whereas the pigmentation loss is unchanged.

      (Dechen et al., 2015)

      Co-expression of foiScer\UAS.T:Zzzz\FLAG moderately exacerbates the rough eye phenotype of flies expressing Zip89BScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.long.

      (Richards et al., 2015)

      The mutant eye phenotype seen in flies co-expressing both ZnT63CVDRC.cUa and Zip42C.1Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4GMR.PFa is enhanced if the flies are also co-expressing foiScer\UAS.T:Zzzz\FLAG.

      The thorax defects caused by co-expression of ZnT63CVDRC.cUa and Zip42C.1Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4pnr-MD237 are enhanced if the flies are also co-expressing foiScer\UAS.T:Zzzz\FLAG.

      (Lye et al., 2013)

      Co-expression of foiScer\UAS.T:Zzzz\FLAG and Zip42C.1Scer\UAS.T:Avic\GFP-EGFP under the control of either Scer\GAL4GMR.PFa or Scer\GAL4pnr-MD237 does not result in a mutant phenotype.

      (Lye et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      dZIPfoiFLAG
      (Richards et al., 2015)
      foiScer\UAS.T:Zzzz\FLAG
      foiUAS.Tag:FLAG
      foiflag
      (Lye et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)