FlyBase Allele Report: Dmel\Catsup[KK103630]

General Information

Symbol

Dmel\Catsup^KK103630

Species

D. melanogaster

Name

FlyBase ID

FBal0232432

Feature type

allele

Associated gene

Dmel\Catsup

Associated Insertion(s)

Carried in Construct

P{KK103630}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK103630}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK103630

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color, with Scer\GAL4^pnr-MD237

(Lye et al., 2012)

lethal, with Scer\GAL4^pnr-MD237

(Lye et al., 2012)

lethal - all die during larval stage, with Scer\GAL4^Tub.PU

(Lye et al., 2012)

some die during pupal stage, with Scer\GAL4^pnr-MD237

(Lye et al., 2012)

visible, with Scer\GAL4^pnr-MD237

(Lye et al., 2012)

Phenotype Manifest In

adult thorax, with Scer\GAL4^pnr-MD237

(Lye et al., 2012)

Detailed Description

Statement

Reference

Expression of Catsup^KK103630 under the control of Scer\GAL4^tub.PU results in early larval lethality.

Expression of Catsup^KK103630 under the control of Scer\GAL4^pnr-MD237 results in a thoracic cleft, pigment loss and late pupal lethality.

(Lye et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Catsup^KK103630, Scer\GAL4^GMR.long is an enhancer of abnormal eye color phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Suppressor of

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Catsup^KK103630, Scer\GAL4^GMR.long is a suppressor | partially of abnormal eye color phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Catsup^KK103630, Scer\GAL4^GMR.PFa is a suppressor of visible phenotype of Scer\GAL4^GMR.PFa, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

NOT Suppressor of

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long is a non-suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Catsup^KK103630, Scer\GAL4^GMR.long is a non-suppressor of abnormal eye color phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Other

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long, ZnT86D^UAS.cDa has partially lethal phenotype

(Dechen et al., 2015)

Catsup^KK103630, Scer\GAL4^pnr-MD237, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa has lethal phenotype

(Lye et al., 2013)

Phenotype Manifest In

Enhancer of

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long is an enhancer of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Suppressor of

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Catsup^KK103630, Scer\GAL4^GMR.PFa is a suppressor of eye phenotype of Scer\GAL4^GMR.PFa, Zip42C.1^UAS.EGFP, ZnT63C^VDRC.cUa

(Lye et al., 2013)

NOT Suppressor of

Statement

Reference

Catsup^KK103630, Scer\GAL4^GMR.long is a non-suppressor of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86D^Scer\UAS.cDa under the control of Scer\GAL4^GMR.long are severely exacerbated by co-expression of Catsup^KK103630 RNAi, which also leads to partial lethality.

The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86D^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.long do not change upon co-expression of Catsup^KK103630 RNAi.

The morphological and pigmentation defects in the adult eye seen upon expression of Zip71B^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.long are strongly ameliorated by co-expression of Catsup^KK103630 RNAi.

(Dechen et al., 2015)

The mutant eye phenotype seen in flies co-expressing both ZnT63C^VDRC.cUa and Zip42C.1^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PFa is suppressed if the flies are also co-expressing Catsup^KK103630.

(Lye et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100095

P{KK103630}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Catsup^KK103630

dZipCATSUP^RNAi

(Dechen et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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