FB2024_03 , released June 25, 2024
Allele: Dmel\Ptp69D4
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General Information
Symbol
Dmel\Ptp69D4
Species
D. melanogaster
Name
FlyBase ID
FBal0104056
Feature type
allele
Associated gene
Dmel\Ptp69D
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    P{lacW}Ptp69D11f3
    (Desai and Purdy, 2003)
    Ptp69D11f3
    (Desai and Purdy, 2003)
    Caused by aberration
    Df(3L)Ptp69D4
    Cytology
    Description

    Deletion removing the first 115bp of the 5' UTR and the entire promoter of Ptp69D and also removing snRNP69D.

    (Desai and Purdy, 2003)

    5' deletion that does not extend into the coding region.

    (Sun et al., 2000)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Ptp69D4 embryos (Df(3L)Ptp69D4 homozygotes in which snRNP69D function has been rescued by snRNP69D+t1.5) show motor axon defects; 18% of ISNb axons, 6% of ISN axons, 9% of SNa axons and 5% of SNc axons show defects.

        (Desai and Purdy, 2003)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        When RhoGAP93BdsRNA.Scer\UAS is driven by Scer\GAL4elav.PLu in a Ptp69D4/Ptp10Dunspecified background no midline crossing defects are seen.

        (Hu, 2005)

        Fas2-positive axons are seen crossing the midline in 95.5% of segments in Ptp10D1/Ptp10D101; Ptp69D4/Ptp69D8ex25 double mutant embryos (this is never seen in wild-type embryos).

        (Sun et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Ptp69D4
        Name Synonyms
        Secondary FlyBase IDs
          References (3)