Nucleotide substitution: G?A. Amino acid replacement: G1102S.
G12739541A
G?A
G1102S | Ptp69D-PA; G1101S | Ptp69D-PB
G1102S
Mutation is in the active site.
Ptp69D20 embryos show motor axon defects; 11% of ISNb axons, 4% of ISN axons, 5% of SNa axons and 3% of SNc axons show defects.