X/Y males homozygous for Su(var)2-11 are almost completely lethal, whereas homozygous X/0 males are almost completely viable. The lethality is mainly concentrated at the embryo stage. The lethal interaction between Su(var)2-11 and Y is correlated with size of the Y chromosome fragments, as tested with Df(YL)S10, Df(YS)S12, and Df(YL)S6.
In X/O males carnitine compounds have a lethal interaction.
mod(mdg4)neo129 suppresses the strong dominant suppressor effect.
Suppresses In(1)wm4 and T(2;3)SbV and enhances the variegation phenotype of In(2R)bwVDe2. Homozygous embryos are semi-viable. The effect of the Su(var)2-11 allele is slightly reduced in heterozygotes with Df(2R)M41A10 (which lacks 2R heterochromatin). The extent of hemizygous lethality is dramatically enhanced in the presence of extra heterochromatin (attachedXX/Y females) whereas the lethality did not occur in the absence of the Y (X/O males).
Dominant suppressor effect for position-effect variegation. Homozygous lethal and semi-sterile in males.
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)03/mod(mdg4)[+]
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)04/mod(mdg4)[+]
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)[+]/mod(mdg4)05
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)06/mod(mdg4)[+]
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)07/mod(mdg4)[+]
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)142Δ32/mod(mdg4)[+]
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)neo129/mod(mdg4)[+]
In(1)wm4h, Su(var)2-11 has suppressor of variegation phenotype, suppressible by mod(mdg4)[+]/mod(mdg4)R32
Su(var)2-11 is an enhancer of abnormal eye color phenotype of lt1/lt11
Su(var)2-1[+], Su(var)208[+], Su(var)2-11, Su(var)208unspecified is an enhancer of abnormal eye color phenotype of lt1/lt11
Su(var)2-11/Su(var)208unspecified is an enhancer of abnormal eye color | recessive phenotype of lt11
Su(var)2-11, Su(var)205unspecified, rlunspecified has visible phenotype
Su(var)2-11/Su(var)2-1216, rlunspecified has visible phenotype
Su(var)2-11, Su(var)208unspecified, rlunspecified has visible phenotype
Su(var)2-11, rlunspecified has visible phenotype
E(ltv)319319, Su(var)2-11, lt11 has viable phenotype
E(ltv)319319, Su(var)2-11, lt11 has abnormal eye color phenotype
Su(var)2-11/Su(var)2-1v9, lt1 has partially lethal | recessive | male phenotype
Su(var)2-11/Su(var)2-1v9, lt11 has partially lethal | recessive | male phenotype
Su(var)2-11 is an enhancer of pigment cell phenotype of lt1/lt11
Su(var)2-1[+], Su(var)208[+], Su(var)2-11, Su(var)208unspecified is an enhancer of pigment cell phenotype of lt1/lt11
Su(var)2-11/Su(var)208unspecified is an enhancer of pigment cell phenotype of lt11
Su(var)2-11 is a suppressor of adult metathoracic segment phenotype of E(z)Trm
Su(var)2-11 is a suppressor of adult prothoracic segment phenotype of E(z)Trm
Su(var)2-11 is a suppressor of adult mesothoracic segment | ectopic phenotype of E(z)Trm
Su(var)2-11 is a suppressor of phenotype of Usp47Evar1
In(1)wm4h, Su(var)2-11, mod(mdg4)07/mod(mdg4)[+] has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)142Δ32/mod(mdg4)[+] has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)neo129/mod(mdg4)[+] has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)[+]/mod(mdg4)R32 has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)03/mod(mdg4)[+] has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)04/mod(mdg4)[+] has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)[+]/mod(mdg4)05 has pigment cell phenotype
In(1)wm4h, Su(var)2-11, mod(mdg4)06/mod(mdg4)[+] has pigment cell phenotype
Su(var)2-11, Su(var)205unspecified, rlunspecified has eye phenotype
Su(var)2-11, Su(var)208unspecified, rlunspecified has eye phenotype
Su(var)2-11/Su(var)2-1216, rlunspecified has eye phenotype
Su(var)2-11, rlunspecified has eye phenotype
E(ltv)319319, Su(var)2-11, lt11 has pigment cell phenotype
Su(var)205unspecified shows semi-lethality with Su(var)2-11 in females with a Y chromosome.
Eye pigmentation in lt11/lt1 flies is reduced if the flies are also carrying Su(var)208unspecified/Su(var)2-11 or Su(var)2-1v9/Su(var)2-11. XY lt11/lt1; Su(var)2-1v9/Su(var)2-11 males have reduced viability, which is restored in XO males. Eye pigmentation is reduced and viability is essentially wild-type in lt11/+ flies that are also carrying or Su(var)2-1v9 and E(ltv)319319.
The effect of loss of one copy of Su(var)2-11 can be rescued by P-element mediated transformation with Su(var)3-7.
non-complementing
Used as the genetic background in a screen to identify enhancers of PEV.