FB2024_03 , released June 25, 2024
Allele: Dmel\msl-1L60
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General Information
Symbol
Dmel\msl-1L60
Species
D. melanogaster
Name
FlyBase ID
FBal0093825
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
msl1L60
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

2kb deletion beginning in the 5' UTR and deleting most of the coding region.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Enhancer of
Suppressor of
Statement
Reference

msl-1L60/msl-1[+] is a suppressor | partially of lethal | male phenotype of ocmL1658N/ocmG1646E

Other
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The viability of SxlfP7B0/+ females is significantly reduced if they also carry one maternally-derived copy of msl-1L60.

One maternally-derived copy of msl-1L60 significantly reduces the viability of scsisB-1 sisA1/+ females so that they show almost complete lethality. One paternally-derived copy of msl-1L60 significantly reduces the viability of scsisB-1 sisA1/+ females.

The ability of P{GMroX1}75C (which carries roX1t4.9) to partially rescue the lethality of roX1ex6/Df(1)52 males is suppressed if the males are also heterozygous for msl-1L60.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
References (17)