2kb deletion beginning in the 5' UTR and deleting most of the coding region.
lethal | male (with msl-1F979Z)
lethal | male (with msl-1K1009X)
lethal | male limited (with msl-1γ269)
msl-1L60 does not increase the fraction of red eye tissue present in males homozygous for P{GMroX1}75C.
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60 has lethal | male phenotype, suppressible | partially by ocmQ1297X/ocm[+]
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60 has lethal | male phenotype, suppressible | partially by ocm[+]/ocmG1646E
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60 has lethal | male phenotype, suppressible | partially by ocmS1590F/ocm[+]
msl-1L60/msl-1[+] is an enhancer of partially lethal | male phenotype of Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9
msl-1L60/msl-1[+] is an enhancer | maternal effect of partially lethal - majority die | dominant | female phenotype of scsisB-1, sisA[+]/sisA1
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60 has lethal | male phenotype
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60, ocmQ1297X/ocm[+] has partially lethal | male phenotype
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60, ocm[+]/ocmG1646E has partially lethal | male phenotype
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60, ocmS1590F/ocm[+] has partially lethal | male phenotype
Df(1)52, P{w+4Δ4.3}, lncRNA:roX1ex6, lncRNA:roX1t4.9, msl-1L60/msl-1[+] has lethal | male phenotype
Sxl[+]/SxlfP7B0, msl-1L60 has partially lethal - majority die | female | maternal effect phenotype
The viability of SxlfP7B0/+ females is significantly reduced if they also carry one maternally-derived copy of msl-1L60.
One maternally-derived copy of msl-1L60 significantly reduces the viability of scsisB-1 sisA1/+ females so that they show almost complete lethality. One paternally-derived copy of msl-1L60 significantly reduces the viability of scsisB-1 sisA1/+ females.
The ability of P{GMroX1}75C (which carries roX1t4.9) to partially rescue the lethality of roX1ex6/Df(1)52 males is suppressed if the males are also heterozygous for msl-1L60.
msl-1L60/msl-1γ269 is rescued by Scer\GAL4αTub84B.PL/msl-1UAS.Tag:FLAG
msl-1L60/msl-1γ269 is not rescued by msl-1mut1.UAS.Tag:FLAG/Scer\GAL4αTub84B.PL
msl-1L60/msl-1γ269 is not rescued by Scer\GAL4αTub84B.PL/msl-1mut3.UAS.Tag:FLAG
msl-1L60/msl-1γ269 is not rescued by Scer\GAL4αTub84B.PL/msl-1mut4.UAS.Tag:FLAG
msl-1L60/msl-1γ269 is not rescued by msl-1mut5.UAS.Tag:FLAG/Scer\GAL4αTub84B.PL
Expression of msl-1Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4αTub84B.PL at 25[o]C completely rescues the male-specific lethality of msl-1L60/msl-1γ269 flies.
Expression of either msl-1mut1.Scer\UAS.T:Zzzz\FLAG, msl-1mut3.Scer\UAS.T:Zzzz\FLAG, msl-1mut4.Scer\UAS.T:Zzzz\FLAG or msl-1mut5.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4αTub84B.PL at 25[o]C fails to rescue the male-specific lethality of msl-1L60/msl-1γ269 flies.