FlyBase Allele Report: Scer\GAL4[G14]

(McCabe et al., 2004, Haghighi et al., 2003, Marques et al., 2003, McCabe et al., 2003, Aberle et al., 2002, Saitoe et al., 2001, Shishido et al., 1998)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with caps^UAS.cSa

(Shishido et al., 1998)

abnormal neuroanatomy, with Fur1^GL01340

(Kim et al., 2015)

abnormal neuroanatomy, with GluRIIA^JF02647

(Sulkowski et al., 2014)

abnormal neuroanatomy, with GluRIIC^JF01854

(Sulkowski et al., 2014)

abnormal neuroanatomy, with GluRIID^JF02035

(Sulkowski et al., 2014)

abnormal neuroanatomy, with GluRIIE^JF01962

(Sulkowski et al., 2014)

abnormal neuroanatomy, with haf^GD14353

(Kurusu et al., 2008)

abnormal neuroanatomy, with Mmus\Prkaca^mC.UAS

(Sulkowski et al., 2014)

abnormal neuroanatomy, with Neto³⁶, Neto^PM.UAS.GFP

(Kim et al., 2015)

abnormal neuroanatomy, with Neto³⁶, Neto^UAS.cSa

(Kim et al., 2015)

abnormal neuroanatomy, with Neto³⁶, Neto^UAS.EGFP

(Kim et al., 2015)

abnormal neuroanatomy, with Neto³⁶, Neto^{UAS.Tag:V5,Tag:polyHis}

(Kim et al., 2015)

abnormal neuroanatomy, with Neto^RNAi.UAS

(Kim et al., 2015)

abnormal neuroanatomy, with Neto^UAS.cSa

(Kim et al., 2015)

abnormal neuroanatomy, with Scer\GAL4^how-24B, dally^UAS.cJa

(Fox and Zinn, 2005)

abnormal neuroanatomy, with tutl^AT02763.UAS

(Al-Anzi and Wyman, 2009)

abnormal neuroanatomy, with tutl^GH08133.UAS

(Al-Anzi and Wyman, 2009)

abnormal neuroanatomy, with tutl^GH15753.UAS

(Al-Anzi and Wyman, 2009)

abnormal neuroanatomy, with tutl^HL01565.UAS

(Al-Anzi and Wyman, 2009)

abnormal neuroanatomy, with tutl^LD28224.UAS

(Al-Anzi and Wyman, 2009)

abnormal neuroanatomy | third instar larval stage, with nmo^K69M.UAS.GFP

(Merino et al., 2009)

abnormal neurophysiology, with cv-c^RNAi.UAS

(Pilgram et al., 2011)

abnormal neurophysiology, with Dys^RNAi.NH2.UAS

(van der Plas et al., 2006)

abnormal neurophysiology | larval stage, with GluRIIB^UAS.cPa

(Han et al., 2023)

abnormal neurophysiology | larval stage | chemical conditional, with Pef^GD8610

(Kikuma et al., 2019)

abnormal neurophysiology | third instar larval stage, with Hsap\LRRK2^UAS.cVa

(Penney et al., 2016)

abnormal neurophysiology | third instar larval stage, with Lrrk^UAS.cIa

(Penney et al., 2016)

lethal - all die before end of larval stage, with Neto³⁶, Neto^PM.UAS.GFP

(Kim et al., 2015)

lethal - all die before end of P-stage, with Vap33^UAS.cRa

(Ratnaparkhi et al., 2008)

lethal - all die before end of pupal stage, with ttv^00681b, ttv^UAS.Tag:MYC

(Ren et al., 2009)

lethal - all die during embryonic stage, with spas^UAS.cSa

(Sherwood et al., 2004)

lethal - all die during P-stage, with COX5B^GD6659

(Kemppainen et al., 2014)

lethal - all die during P-stage, with COX6B^GD13061

(Kemppainen et al., 2014)

partially lethal - majority die, with Hsap\SMN1^UAS.cMa

(Borg and Cauchi, 2013)

some die during embryonic stage, with spas^UAS.cSa

(Sherwood et al., 2004)

some die during larval stage, with Dcr-2^UAS.cDa, Fur1^GL01340

(Kim et al., 2015)

some die during larval stage | heat sensitive, with Fur1^GL01340

(Kim et al., 2015)

some die during pharate adult stage, with Vap33^UAS.cRa

(Ratnaparkhi et al., 2008)

some die during pupal stage, with ttv^00681b, ttv^UAS.Tag:MYC

(Ren et al., 2009)

wild-type, with wit^{UAS.ΔC.Tag:FLAG}

(Aberle et al., 2002)

Phenotype Manifest In

abdominal anterior fascicle & synapse, with caps^UAS.cSa

(Shishido et al., 1998)

abdominal ventral longitudinal muscle 2 & synapse, with caps^UAS.cSa

(Shishido et al., 1998)

embryonic/larval neuromuscular junction, with Neto³⁶, Neto^UAS.EGFP

(Kim et al., 2015)

embryonic/larval neuromuscular junction, with Neto³⁶, Neto^{UAS.Tag:V5,Tag:polyHis}

(Kim et al., 2015)

embryonic/larval neuromuscular junction | larval stage, with GluRIIB^UAS.cPa

(Han et al., 2023)

embryonic/larval neuromuscular junction | third instar larval stage, with Hsap\LRRK2^UAS.cVa

(Penney et al., 2016)

embryonic/larval neuromuscular junction | third instar larval stage, with Lrrk^UAS.cIa

(Penney et al., 2016)

larval abdominal segmental nerve, with Scer\GAL4^how-24B, dally^UAS.cJa

(Fox and Zinn, 2005)

larval intersegmental nerve branch ISNb of A1-7, with haf^GD14353

(Kurusu et al., 2008)

larval intersegmental nerve branch ISNd of A1-7, with tutl^AT02763.UAS

(Al-Anzi and Wyman, 2009)

larval intersegmental nerve branch ISNd of A1-7, with tutl^GH08133.UAS

(Al-Anzi and Wyman, 2009)

larval intersegmental nerve branch ISNd of A1-7, with tutl^GH15753.UAS

(Al-Anzi and Wyman, 2009)

larval intersegmental nerve branch ISNd of A1-7, with tutl^HL01565.UAS

(Al-Anzi and Wyman, 2009)

larval intersegmental nerve branch ISNd of A1-7, with tutl^LD28224.UAS

(Al-Anzi and Wyman, 2009)

larval transverse nerve, with tutl^AT02763.UAS

(Al-Anzi and Wyman, 2009)

larval transverse nerve, with tutl^GH08133.UAS

(Al-Anzi and Wyman, 2009)

larval transverse nerve, with tutl^GH15753.UAS

(Al-Anzi and Wyman, 2009)

larval transverse nerve, with tutl^HL01565.UAS

(Al-Anzi and Wyman, 2009)

larval transverse nerve, with tutl^LD28224.UAS

(Al-Anzi and Wyman, 2009)

motor neuron | larval stage, with GluRIIB^UAS.cPa

(Han et al., 2023)

neuromuscular junction, with cv-c^RNAi.UAS

(Pilgram et al., 2011)

NMJ bouton | third instar larval stage, with nmo^K69M.UAS.GFP

(Merino et al., 2009)

somatic muscle & microtubule, with spas^UAS.cSa

(Sherwood et al., 2004)

synapse | ectopic, with caps^UAS.cSa

(Shishido et al., 1998)

terminal bouton, with Fur1^GL01340

(Kim et al., 2015)

terminal bouton, with GluRIIA^JF02647

(Sulkowski et al., 2014)

terminal bouton, with GluRIIC^JF01854

(Sulkowski et al., 2014)

terminal bouton, with GluRIID^JF02035

(Sulkowski et al., 2014)

terminal bouton, with GluRIIE^JF01962

(Sulkowski et al., 2014)

terminal bouton, with Mmus\Prkaca^mC.UAS

(Sulkowski et al., 2014)

terminal bouton, with Neto³⁶, Neto^PM.UAS.GFP

(Kim et al., 2015)

terminal bouton, with Neto³⁶, Neto^UAS.cSa

(Kim et al., 2015)

terminal bouton, with Neto^RNAi.UAS

(Kim et al., 2015)

terminal bouton, with Neto^UAS.cSa

(Kim et al., 2015)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

COX5B^GD6659, Scer\GAL4^G14 has lethal - all die during P-stage phenotype, suppressible by Cint\AOX^UAS.cFa, Scer\GAL4^G14

(Kemppainen et al., 2014)

COX5B^GD6659, Scer\GAL4^G14 has lethal - all die during P-stage phenotype, suppressible | partially by Cint\AOX^αTub84B.PK

(Kemppainen et al., 2014)

NOT Enhancer of

Statement

Reference

Scer\GAL4^G14/Dys^RNAi.NH2.UAS is a non-enhancer of abnormal neurophysiology phenotype of wit^B11/wit^A12

(van der Plas et al., 2006)

Suppressor of

Statement

Reference

Cint\AOX^UAS.cFa, Scer\GAL4^G14 is a suppressor of lethal - all die during P-stage phenotype of COX5B^GD6659, Scer\GAL4^G14

(Kemppainen et al., 2014)

Scer\GAL4^G14/Dys^GS12472 is a suppressor | partially of abnormal neurophysiology | dominant phenotype of cv-c¹

(Pilgram et al., 2011)

Scer\GAL4^G14/esg^EP684 is a suppressor of bang sensitive phenotype of eas²

(Hekmat-Scafe et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^G14/gbb^UAS.cKa is a non-suppressor of abnormal neuroanatomy phenotype of Neto¹⁰⁹

(Sulkowski et al., 2014)

Scer\GAL4^G14/cv-c^UAS.cDa is a non-suppressor of abnormal neurophysiology | dominant phenotype of Dys^E6

(Pilgram et al., 2011)

Scer\GAL4^G14/tkv^{Q253D.UAS.cNb} is a non-suppressor of abnormal neurophysiology phenotype of Impβ11⁷⁰

(Higashi-Kovtun et al., 2010)

Scer\GAL4^G14/sax^{Q263D.UAS.Tag:HA} is a non-suppressor of abnormal neurophysiology phenotype of Impβ11⁷⁰

(Higashi-Kovtun et al., 2010)

Scer\GAL4^G14/Dys^RNAi.NH2.UAS is a non-suppressor of abnormal neurophysiology phenotype of wit^B11/wit^A12

(van der Plas et al., 2006)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^G14/Dys^GS12472 is a suppressor | partially of neuromuscular junction phenotype of cv-c¹

(Pilgram et al., 2011)

NOT Suppressor of

Statement

Reference

Scer\GAL4^G14/gbb^UAS.cKa is a non-suppressor of terminal bouton phenotype of Neto¹⁰⁹

(Sulkowski et al., 2014)

Scer\GAL4^G14/cv-c^UAS.cDa is a non-suppressor of neuromuscular junction phenotype of Dys^E6

(Pilgram et al., 2011)

Scer\GAL4^G14/tkv^{Q253D.UAS.cNb} is a non-suppressor of bouton phenotype of Impβ11⁷⁰

(Higashi-Kovtun et al., 2010)

Scer\GAL4^G14/sax^{Q263D.UAS.Tag:HA} is a non-suppressor of bouton phenotype of Impβ11⁷⁰

(Higashi-Kovtun et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^G14/Neto^UAS.EGFP rescues Neto³⁶

(Kim et al., 2015)

Scer\GAL4^G14/Neto^UAS.cSa rescues Neto³⁶

(Ramos et al., 2015)

Scer\GAL4^G14/Neto^UAS.β rescues Neto³⁶

(Ramos et al., 2015)

Scer\GAL4^G14/Neto^{Δintra.UAS.EGFP} rescues Neto³⁶

(Ramos et al., 2015)

Scer\GAL4^G14/Neto^UAS.EGFP rescues Neto³⁶

(Kim et al., 2012)

Scer\GAL4^G14/cv-c^UAS.cDa rescues cv-c¹

(Pilgram et al., 2011)

ttv^UAS.Tag:MYC/Scer\GAL4^G14 rescues ttv^00681b

(Ren et al., 2009)

Scer\GAL4^G14/tok^{UAS.cSa.Tag:HA} rescues tok^K788/tok^D427

(Meyer and Aberle, 2006)

Scer\GAL4^G14/tok^{UAS.cSa.Tag:HA} rescues tok^Δ2-41/tok^E1

(Serpe and O'Connor, 2006)

Scer\GAL4^G14/Dys^GS12472 rescues Dys^GS12472/Dys^E6

(van der Plas et al., 2006)

Partially rescues

Scer\GAL4^G14/Nprl3^{UASp.Tag:FLAG,Tag:HA} partially rescues Df(3L)ED4515/Nprl3¹

(Wei et al., 2016)

Scer\GAL4^G14/Neto^CA.UAS.GFP partially rescues Neto³⁶

(Kim et al., 2015)

Scer\GAL4^G14/Neto^PM.UAS.GFP partially rescues Neto³⁶

(Kim et al., 2015)

Scer\GAL4^G14/Neto^UAS.EGFP partially rescues Neto³⁶

(Kim et al., 2012)

Scer\GAL4^G14/Neto^{UAS.Tag:V5,Tag:polyHis} partially rescues Neto³⁶

(Kim et al., 2012)

Scer\GAL4^G14/park^UAS.cGa partially rescues park^Z3678/park²⁵

(Vincent et al., 2012)

Scer\GAL4^G14/park^UAS.cGa partially rescues park²⁵

(Vincent et al., 2012)

Scer\GAL4^G14/tum^{UAS.Z.Tag:MYC} partially rescues tum^DH15

(Guerin and Kramer, 2009)

Scer\GAL4^G14/gbb^UAS.cKa partially rescues gbb²/gbb¹

(McCabe et al., 2003)

Fails to rescue

Scer\GAL4^G14/Sol1^UAS.cKa fails to rescue Sol1^bk1

(Kiragasi et al., 2020)

Scer\GAL4^G14/beag^UAS.cBa fails to rescue beag¹/Df(3R)Exel6151

(Beck et al., 2012)

Scer\GAL4^G14/Smu1^UAS.cBa fails to rescue Smu1^f03090/Df(3R)Exel6182

(Beck et al., 2012)

Scer\GAL4^G14/Smn^UAS.Tag:FLAG fails to rescue Smn^X7

(Imlach et al., 2012)

Scer\GAL4^G14/Adar^3.4.UAS fails to rescue Adar^5G1

(Bhogal et al., 2011)

Scer\GAL4^G14/trio^UAS.cBa fails to rescue trio^6A/trio^S137203

(Ball et al., 2010)

Scer\GAL4^G14/Impβ11^UAS.EGFP fails to rescue Impβ11⁷⁰

(Higashi-Kovtun et al., 2010)

Scer\GAL4^G14/nmo^UAS.cUa.GFP fails to rescue nmo^P1/Df(3L)Exel6279

(Merino et al., 2009)

Scer\GAL4^G14/Med^UAS.cSa fails to rescue Med^C246/Med³

(McCabe et al., 2004)

Scer\GAL4^G14/Syx1A^UAS.cBa fails to rescue Syx1A^L371

(Saitoe et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

D. Lin and C.S. Goodman

(Shishido et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^G14

Scer\GAL4^G14

Name Synonyms

Secondary FlyBase IDs

References (60)

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