FlyBase Allele Report: Scer\GAL4[e33C]

General Information

Symbol

Scer\GAL4^e33C

Species

S. cerevisiae

Name

FlyBase ID

FBal0042576

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{en2.4-GAL4}e33C

Carried in Construct

Also Known As

e33c-Gal4, e33CGAL4, GAL4-e33c, e33C

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Brand, 1997.6.30, Harrison et al., 1995)

Progenitor genotype

Associated Insertion(s)

P{en2.4-GAL4}e33C

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{en2.4-GAL4}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

No Assay Recorded

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

larval ventral nerve cord

(Brand, 1997.6.30)

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

embryonic/larval hemocyte

(Matova and Anderson, 2006)

embryonic/larval lymph gland

(Khadilkar et al., 2014, Matova and Anderson, 2006)

embryonic/larval epidermis

(Matova and Anderson, 2006)

third instar larval stage

Malpighian tubule

(Harrison et al., 1995)

embryonic/larval digestive system

(Harrison et al., 1995)

embryonic/larval brain

(Harrison et al., 1995)

embryonic/larval lymph gland

(Harrison et al., 1995)

tracheal section

(Harrison et al., 1995)

adult optic lobe

(Harrison et al., 1995)

Additional Information

Statement

Reference

Drives expression widely in the embryonic/larval lymph gland and in hemocytes.

(FlyBase Curators, 2017)

During embryogenesis there is expression along the midline of the central nervous system.

(Brand, 1997.6.30)

Expression in the lymph gland is uniform.

(Harrison et al., 1995)

Marker for

embryonic/larval lymph gland

(Khadilkar et al., 2014)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | larval stage, with dlp^GD3592

(Rodrigues et al., 2021)

abnormal developmental rate, with asrij^C.UAS

(Sinha et al., 2013)

abnormal immune response | adult stage, with Arf1^GD12522

(Khadilkar et al., 2017)

abnormal immune response | adult stage, with asrij^GD2167

(Khadilkar et al., 2017)

abnormal immune response | larval stage, with dlp^GD3592

(Rodrigues et al., 2021)

increased cell number | third instar larval stage, with Drp1^UAS.cDa

(Ray et al., 2021)

increased cell number | third instar larval stage, with Marf^JF01650

(Ray et al., 2021)

increased mortality during development, with dlp^GD3592

(Rodrigues et al., 2021)

increased occurrence of cell division | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

lethal, with Ggal\A-Myb^UAS.cDa

(Davidson et al., 2005)

lethal, with Ggal\c-Myb^UAS.cDa

(Davidson et al., 2005)

lethal - all die before end of pupal stage, with Pvf2^UAS.cMa

(Munier et al., 2002)

lethal - all die during embryonic stage, with lwr^DN.UAS

(Huang et al., 2005)

lethal - all die during embryonic stage, with Pvr^UAS.cMa

(Munier et al., 2002)

some die during embryonic stage, with lwr^DN.UAS

(Huang et al., 2005)

some die during embryonic stage, with Pvr^UAS.cMa

(Munier et al., 2002)

some die during pupal stage, with Pvf2^UAS.cMa

(Munier et al., 2002)

Phenotype Manifest In

cortical zone of lymph gland primary lobe | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

embryonic/larval crystal cell, with Pvf2^UAS.cMa

(Munier et al., 2002)

embryonic/larval crystal cell | ectopic, with lz^UAS.cBa

(Fossett et al., 2003)

embryonic/larval crystal cell | ectopic, with srp^NC.F.UAS

(Fossett et al., 2003)

embryonic/larval crystal cell | increased number | third instar larval stage, with Drp1^UAS.cDa

(Ray et al., 2021)

embryonic/larval crystal cell | increased number | third instar larval stage, with Marf^JF01650

(Ray et al., 2021)

embryonic/larval crystal cell | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

embryonic/larval hemocyte | increased number, with lwr^DN.UAS

(Huang et al., 2005)

embryonic/larval hemocyte | increased number, with Pvf2^UAS.cMa

(Munier et al., 2002)

embryonic/larval hemocyte | second instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

embryonic/larval hemocyte | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

embryonic/larval lymph gland | larval stage, with dlp^GD3592

(Rodrigues et al., 2021)

embryonic/larval lymph gland | third instar larval stage, with asrij^GD2167

(Ray et al., 2021)

embryonic/larval lymph gland | third instar larval stage, with asrij^UAS.cKa

(Ray et al., 2021)

embryonic/larval plasmatocyte, with asrij^C.UAS

(Sinha et al., 2013)

embryonic/larval plasmatocyte, with Pvf2^UAS.cMa

(Munier et al., 2002)

embryonic/larval plasmatocyte | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

embryonic epidermis, with lwr^DN.UAS

(Huang et al., 2005)

lamellocyte | larval stage, with dlp^GD3592

(Rodrigues et al., 2021)

mitochondrion | third instar larval stage, with asrij^GD2167

(Ray et al., 2021)

mitochondrion | third instar larval stage, with asrij^UAS.cKa

(Ray et al., 2021)

posterior signaling center of lymph gland primary lobe | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

primary lobe of embryonic/larval lymph gland | third instar larval stage, with Drp1^UAS.cDa

(Ray et al., 2021)

primary lobe of embryonic/larval lymph gland | third instar larval stage, with Marf^JF01650

(Ray et al., 2021)

prohemocyte | third instar larval stage, with asrij^GD2167

(Ray et al., 2021)

prohemocyte | third instar larval stage, with asrij^UAS.cKa

(Ray et al., 2021)

secondary lobe of embryonic/larval lymph gland | ectopic | third instar larval stage, with asrij^NIG.13533R

(Kulkarni et al., 2011)

secondary lobe of embryonic/larval lymph gland | third instar larval stage, with Arf1^GD12522

(Khadilkar et al., 2014)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Drp1^UAS.cDa, Scer\GAL4^e33C has increased cell number | third instar larval stage phenotype, enhanceable by asrij⁹/asrij⁹

(Ray et al., 2021)

Marf^JF01650, Scer\GAL4^e33C has increased cell number | third instar larval stage phenotype, enhanceable by asrij⁹/asrij⁹

(Ray et al., 2021)

Enhancer of

Statement

Reference

Scer\GAL4^e33C/Drp1^UAS.cDa is an enhancer of increased cell number | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Marf^JF01650 is an enhancer of increased cell number | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Suppressor of

Statement

Reference

Scer\GAL4^e33C/Mmus\Cd8a^UAS.cLa.EGFP is a suppressor of abnormal developmental rate phenotype of asrij⁹

(Sinha et al., 2013)

Scer\GAL4^e33C, dl^UASp.cMa, dl¹ is a suppressor of lethal | larval stage phenotype of Dif¹

(Matova and Anderson, 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Marf^JF01650, Scer\GAL4^e33C has embryonic/larval crystal cell | third instar larval stage | increased number phenotype, enhanceable by asrij⁹/asrij⁹

(Ray et al., 2021)

Marf^JF01650, Scer\GAL4^e33C has embryonic/larval lymph gland | third instar larval stage phenotype, enhanceable by asrij⁹/asrij⁹

(Ray et al., 2021)

Drp1^UAS.cDa, Scer\GAL4^e33C has embryonic/larval lymph gland | third instar larval stage phenotype, enhanceable by asrij⁹/asrij⁹

(Ray et al., 2021)

Drp1^UAS.cDa, Scer\GAL4^e33C has embryonic/larval crystal cell | third instar larval stage | increased number phenotype, enhanceable by asrij⁹/asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C, lz^UAS.cBa has embryonic/larval crystal cell | ectopic phenotype, enhanceable by srp^NC.F.UAS/Scer\GAL4^e33C

(Fossett et al., 2003)

Scer\GAL4^e33C, srp^NC.F.UAS has embryonic/larval crystal cell | ectopic phenotype, enhanceable by Scer\GAL4^e33C/lz^UAS.cBa

(Fossett et al., 2003)

Enhancer of

Statement

Reference

Scer\GAL4^e33C/Drp1^UAS.cDa is an enhancer of embryonic/larval lymph gland | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Drp1^UAS.cDa is an enhancer of primary lobe of embryonic/larval lymph gland | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Marf^JF01650 is an enhancer of embryonic/larval lymph gland | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Marf^JF01650 is an enhancer of primary lobe of embryonic/larval lymph gland | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

srp^NC.F.UAS/Scer\GAL4^e33C is an enhancer of embryonic/larval crystal cell | ectopic phenotype of Scer\GAL4^e33C, lz^UAS.cBa

(Fossett et al., 2003)

Scer\GAL4^e33C/lz^UAS.cBa is an enhancer of embryonic/larval crystal cell | ectopic phenotype of Scer\GAL4^e33C, srp^NC.F.UAS

(Fossett et al., 2003)

Suppressor of

Statement

Reference

Scer\GAL4^e33C/Drp1^UAS.cDa is a suppressor | partially of mitochondrion | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Drp1^UAS.cDa is a suppressor | partially of prohemocyte | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Drp1^UAS.cDa is a suppressor | partially of embryonic/larval lymph gland | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Marf^JF01650 is a suppressor | partially of mitochondrion | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Marf^JF01650 is a suppressor | partially of prohemocyte | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/Marf^JF01650 is a suppressor | partially of embryonic/larval lymph gland | third instar larval stage phenotype of asrij⁹

(Ray et al., 2021)

Scer\GAL4^e33C/asrij^UAS.cKa is a suppressor of prohemocyte | larval stage phenotype of kn^col-1

(Sinha et al., 2013)

Scer\GAL4^e33C/Mmus\Cd8a^UAS.cLa.EGFP is a suppressor of embryonic/larval plasmatocyte phenotype of asrij⁹

(Sinha et al., 2013)

Scer\GAL4^e33C, dl^UASp.cMa, dl¹ is a suppressor of hemocyte phenotype of Dif¹

(Matova and Anderson, 2006)

Scer\GAL4^e33C, dl^UASp.cMa, dl¹ is a suppressor of hemolymph phenotype of Dif¹

(Matova and Anderson, 2006)

Scer\GAL4^e33C/Ggal\B-Myb^UAS.cDa is a suppressor of hemocyte & nucleus phenotype of Myb^MH107

(Davidson et al., 2005)

Scer\GAL4^e33C/Ggal\B-Myb^UAS.cDa is a suppressor of embryonic/larval lymph gland phenotype of Myb^MH107

(Davidson et al., 2005)

Scer\GAL4^e33C/Ggal\B-Myb^UAS.cDa is a suppressor of embryonic/larval crystal cell phenotype of Myb^MH107

(Davidson et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^e33C/Ggal\A-Myb^UAS.cDa is a non-suppressor of embryonic/larval crystal cell phenotype of Myb^MH107

(Davidson et al., 2005)

Scer\GAL4^e33C/Ggal\c-Myb^UAS.cDa is a non-suppressor of embryonic/larval crystal cell phenotype of Myb^MH107

(Davidson et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^e33C/Arf1^UAS.cKa rescues Arf1^GD12522

(Khadilkar et al., 2017)

asrij^N.UAS/Scer\GAL4^e33C rescues asrij⁹

(Sinha et al., 2013)

Scer\GAL4^e33C/Myb^UAS.cDa rescues Myb^MH107

(Davidson et al., 2005)

Scer\GAL4^e33C/Adgf-A^UAS.Tag:MYC rescues Dp(3;3)Karel

(Dolezal et al., 2005)

Scer\GAL4^e33C/Adgf-A^UAS.Tag:MYC rescues Dp(3;3)Karel

(Dolezal et al., 2005)

Partially rescues

Scer\GAL4^e33C/asrij^UAS.cKa partially rescues asrij⁹

(Kulkarni et al., 2011)

Scer\GAL4^e33C/cact^UAS.cQa partially rescues cact³/cact⁷

(Qiu et al., 1998)

Scer\GAL4^e33C/cact^UAS.cQa partially rescues cact³/cact⁵

(Qiu et al., 1998)

Fails to rescue

Scer\GAL4^e33C/asrij^C.UAS fails to rescue asrij⁹

(Sinha et al., 2013)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^e33C

Scer\GAL4^e33C

Name Synonyms

Secondary FlyBase IDs

References (22)

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