Expression of lwrDN.Scer\UAS under the control of either Scer\GAL4tub or Scer\GAL4e33C prevents hatching in 18% of embryos and causes cuticle defects in some embryos. Expression of lwrDN.Scer\UAS under the control of either Scer\GAL4Cg.PA or Scer\GAL4e33C leads to increased levels of hemocytes, particularly of lamellocytes, in the hemolymph of larvae compared to wild type. In contrast, expression with the fat body-specific Scer\GAL4Lsp2.PH driver does not affect hemocyte levels.