Amino acid replacement: E574C. Nucleotide substitution: C1721G.
Nucleotide substitution: C1721G. Amino acid replacement: S574C.
C3196219G
C1721G
S574C | Hsp83-PA; S574C | Hsp83-PB
S574C
Hsp83e3A has no effect on an invariant bristle trait (thoracic and scutellar bristles were analysed). Hsp83e3A has a significant effect on a variable bristle trait (the sternopleural, orbital, ocellar and vibrissa and carina bristles were analysed); there is a significant difference in trait mean compared to the background strain in which the Hsp83e3A mutation was induced.
Viable in transheterozygous combination with either Hsp8313F3 or Hsp839J1; males are sterile and females are weakly fertile. Hsp839J1/Hsp83e3A males show some defects during spermatogenesis. The number and shape of spermatocytes within 16-cell cysts are mostly normal (5-10% are abnormal). Some motile sperm are present. Hsp8313F3/Hsp83e3A males show defects during spermatogenesis. The number and shape of spermatocytes within 16-cell cysts are mostly normal (5-10% are abnormal). Spermatids with variable number, size and shape of nuclei and nebenkern are seen. Needle-shaped crystals are present throughout developing spermatocytes and spermatids. Individualised sperm are present but they are not motile and are fragile. Hsp8308445/Hsp83e3A males show defects during spermatogenesis. The number and shape of spermatocytes within 16-cell cysts are mostly normal (5-10% are abnormal). Spermatids with variable number, size and shape of nuclei and nebenkern are seen. Crystal structures are seen in some developmental stages. Individualised sperm are present but they are not motile and are fragile.
Mutation fails to genetically interact with sevS11.T:Hsap\MYC, 'sev351', phl12 or phl::tor12D.hs.sev.
Hsp83e3A is rescued by Hsp83+t7.5
Hsp83e3A is rescued by Hsp83+tpSPHW