FB2024_03 , released June 25, 2024
Allele: Dmel\lz48f
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General Information
Symbol
Dmel\lz48f
Species
D. melanogaster
Name
FlyBase ID
FBal0011783
Feature type
allele
Associated gene
Dmel\lz
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
bis(2-chloroethyl) sulfide
(Green and Green, 1956)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      lz48f adults have a severe mutant eye phenotype. Ectopic cell death is seen in third larval instar eye discs.

      (Siddall et al., 2003)

      Homozygotes show general disruption of the ommatidial array in the eye. The eyes have mottled pigmentation and black pock marks are visible on the surface of the eye.

      (Batterham et al., 1996)

      The antennal funiculus is reduced in size in hemizygous males. The number of large and small basiconic sensilla on the antennal funiculus is greatly reduced, and the number of trichoid sensilla on the antennal funiculus is increased. The number of coeloconic sensilla on the antennal funiculus is normal. The density of the coeloconic and trichoid sensilla on the antennal funiculus is increased and the density of the small basiconic sensilla on the antennal funiculus is decreased compared to wild-type.

      (Stocker et al., 1993)

      Only 20 basiconic sensilla are found on the funiculus in lz48f flies. The antennal glomeruli V are missing. Antennal glomeruli VL2 and DL2 usually appear fused.

      (Stocker and Gendre, 1988)

      Eyes are greatly reduced in size and have a smooth surface in homozygous flies. Red eye pigment is sparse and confined primarily to the margin of the eye. Tarsal claws are vestigial. The spermathecae and pars ovariae are absent in homozygous females.

      (Green and Green, 1956)

      spectacle; tarsal structures reduced or absent; spermathecae absent; parovaria absent female-sterile

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      lz48f has phenotype, non-suppressible by su(Hw)2

      (Lindsley and Grell, 1968)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Lindsley, June 1948.

      Comments
      Comments

      lz48f maps to the lozenge sublocus of lz.

      (Batterham et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      lz48f
      Name Synonyms
      Secondary FlyBase IDs
        References (6)