FlyBase Allele Report: Dmel\Ser[CS94]

General Information

Symbol

Dmel\Ser^CS94

Species

D. melanogaster

Name

FlyBase ID

FBal0052104

Feature type

allele

Associated gene

Dmel\Ser

Associated Insertion(s)

Carried in Construct

Also Known As

Ser^94C

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Couso et al., 1995)

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | recessive

(Klein and Martinez Arias, 1998)

Phenotype Manifest In

wing

(Klein and Martinez Arias, 1998, Klein and Martinez Arias, 1998, Couso et al., 1995)

wing disc (with Ser^RX106)

(Klein, 2003, Klein and Martinez Arias, 1999)

Detailed Description

Statement

Reference

Ser^RX106/Ser^CS94 animals show loss of wing disc tissue.

(Klein and Martinez Arias, 1999)

Ser^CS94/Ser^RX106 flies develop a very small wing and hinge.

(Klein and Martinez Arias, 1998)

Ser^CS94/Ser^RX106 flies have a small marginless wing blade.

(Klein and Martinez Arias, 1998)

Mitotic clones on the dorsal surface that reach the wing margin cause a ripped wing phenotype. Ventral clones and any internal clones have no phenotype.

(Couso et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ser^CS94/Ser[+] is an enhancer of visible phenotype of fj^N7

(Buckles et al., 2001)

Other

Statement

Reference

Ser^CS94/Ser[+], dx²⁴ has viable phenotype

(Fuwa et al., 2006)

Ser^CS94/Ser[+], dx¹⁵² has lethal phenotype

(Fuwa et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ser^CS94 has phenotype, enhanceable by wg^S84

(Couso et al., 1995)

Suppressed by

Statement

Reference

Ser^CS94/Ser^RX106 has wing disc phenotype, suppressible by l(2)gd1^d7

(Klein, 2003)

Ser^CS94/Ser^RX106 has wing disc phenotype, suppressible by Delta^UAS.cHa/Scer\GAL4^dpp.blk1

(Klein and Martinez Arias, 1999)

Ser^CS94/Ser^RX106 has wing phenotype, suppressible by Scer\GAL4^dpp.blk1/vg^UAS.cKa

(Klein and Martinez Arias, 1998)

NOT suppressed by

Statement

Reference

Ser^CS94 has wing phenotype, non-suppressible by wg^UAS.cGa/Scer\GAL4^dpp.blk1

(Klein and Martinez Arias, 1998)

Enhancer of

Statement

Reference

Ser^CS94/Ser[+] is an enhancer of leg joint phenotype of fj^N7

(Buckles et al., 2001)

NOT Suppressor of

Statement

Reference

Ser^CS94/Ser^RX106 is a non-suppressor of anterior dorsocentral bristle phenotype of Scer\GAL4^klu-G410, fng^UAS.cKa

(Klein and Martinez Arias, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

The loss of wing disc tissue seen in Ser^RX106/Ser^CS94 animals is rescued by Dl^Scer\UAS.cHa expressed under the control of Scer\GAL4^dpp.blk1.

(Klein and Martinez Arias, 1999)

Scer\GAL4^dpp.blk1-mediated expression of vg^Scer\UAS.cKa substantially rescues the wing blade.

(Klein and Martinez Arias, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ser^94C

(Fuwa et al., 2006, Klein, 2003, Buckles et al., 2001, Klein and Martinez Arias, 1999, Klein and Martinez Arias, 1998)

Ser^94c

(Klein and Martinez Arias, 1998)

Ser^CS94

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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