l(2)05282, DEXT1, l(2)00681, l(2)k03617
acetylglucosaminyltransferase - involved in heparan sulfate proteoglycan biosynthesis - affects diffusion of Wingless, Hedgehog and Decapentaplegic
Please see the JBrowse view of Dmel\ttv for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Stop-codon suppression (UAG) postulated; FBrf0234051.
Gene model reviewed during 6.25
3.8 (longest cDNA)
760 (aa); 80 (kD observed)
Interacts with sau (PubMed:23720043).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ttv using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\ttv in JBrowse36 recombinants in 31,272 progeny.
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
ttv is required for normal germ cell migration in the developing embryo.
8 alleles of l(2)SH0631 recovered in a P-insertion screen.
ttv is involved in heparan sulfate proteoglycan synthesis.
Mutants show maternal effect segment polarity phenotypes.
Mutants isolated in a screen of the second chromosome identifying genes affecting disc morphology.
Isolated in a screen for lethal mutations affecting segmentation.
The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation.
Source for merge of: ttv l(2)00681
Source for merge of: ttv l(2)05282 l(2)k03617
Source for merge of: ttv l(2)SH0631
l(2)k03906b may correspond to ttv: the P{lacW}l(2)k03906bk03906b insertion maps within the transcription unit.
'tout-velu' means 'all hair' in French.