FB2024_03 , released June 25, 2024
Allele: Dmel\ttv205
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General Information
Symbol
Dmel\ttv205
Species
D. melanogaster
Name
FlyBase ID
FBal0154410
Feature type
allele
Associated gene
Dmel\ttv
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Takei et al., 2004)
Progenitor genotype
Cytology
Description

Amino acid replacement: G447D.

(Takei et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:14,582,984..14,582,984 [+]
Nucleotide change:

G14582984A

Amino acid change:

G447D | ttv-PA; G447D | ttv-PB; G447D | ttv-PD

Reported amino acid change:

G447D

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Takei et al., 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ttv524/ttv205 animals die as pupae with small eyes and legs. Third instar larvae have smaller discs than the wild type, and in particular, their wing discs are narrower in an anterior-posterior direction. Tissue is deleted within somatic clones of ttv205 homozygous cells in the adult wing.

      (Takei et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      ttv00681b

      (Takei et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ttv205
      Name Synonyms
      Secondary FlyBase IDs
        References (1)